Send us a text

The mysterious connection between perimenopause and histamine intolerance finally explained! If you've wondered why your perimenopause symptoms feel more intense than what friends describe, this episode reveals the hidden mechanism making your experience uniquely challenging.

Perimenopause isn't the steady hormone decline many expect—it's a rollercoaster where estrogen spikes trigger mast cells to release histamine while simultaneously reducing your body's ability to break it down. Meanwhile, progesterone—your body's natural "calm down" signal for mast cells—steadily declines, creating the perfect storm for histamine overload. This explains why symptoms like hot flashes, migraines, anxiety, and digestive issues can feel overwhelming during this transition.

What makes diagnosis particularly frustrating is how perimenopause and histamine symptoms mirror each other. Doctors often dismiss everything as "just hormones" when histamine is actually amplifying your experience. Even birth control, frequently prescribed during perimenopause, comes with complexities—synthetic hormones can still trigger histamine reactions in sensitive individuals, explaining why some women feel worse on hormonal contraceptives.

The most powerful takeaway? You're not imagining things or overreacting. Your body is navigating the double impact of shifting hormones and histamine reactivity. Simple strategies like stabilizing blood sugar, managing stress, and proper hydration can make a significant difference in how you feel. When you understand this connection, you can stop blaming yourself and start finding practical ways to feel more like yourself again during this transformative life stage.

Have you noticed your histamine symptoms changing during different phases of your cycle? Share your experience or reach out directly at Teresa@histaminehealthcoach.com—I'd love to hear your story.

Follow me on Instagram