• Electroacupuncture and Parkinson’s Disease: A New Mechanistic Insight

  • 2025/04/09
  • 再生時間: 11 分
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Electroacupuncture and Parkinson’s Disease: A New Mechanistic Insight

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  • This article from Acupuncture Today explores a new mechanistic insight into how electroacupuncture (EA) may benefit Parkinson's disease (PD). While conventional PD treatments focus on dopamine, this research highlights EA's potential as an adjunctive therapy by demonstrating improvements in motor function in a PD rat model independent of dopamine restoration. The study, which induced a PD-like state in rats, found that EA applied to the GV 16 (Fengfu) and GV 20 (Baihui) acupoints significantly improved locomotion and balance. Importantly, the researchers discovered that EA modulated glutamate signaling in the corticostriatal pathway, a crucial neural circuit for movement, reversing pathological changes in striatal neurons. Blocking this glutamate regulation negated EA's therapeutic effects. This study provides scientific support for the traditional East Asian medicine view of these acupoints as "Sea of Marrow" points linked to brain health and suggests that consistent EA treatment, particularly early on, could be valuable in PD management. Although human studies are needed, this research offers a promising avenue for acupuncture practitioners to consider when integrating EA into PD care.

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あらすじ・解説

This article from Acupuncture Today explores a new mechanistic insight into how electroacupuncture (EA) may benefit Parkinson's disease (PD). While conventional PD treatments focus on dopamine, this research highlights EA's potential as an adjunctive therapy by demonstrating improvements in motor function in a PD rat model independent of dopamine restoration. The study, which induced a PD-like state in rats, found that EA applied to the GV 16 (Fengfu) and GV 20 (Baihui) acupoints significantly improved locomotion and balance. Importantly, the researchers discovered that EA modulated glutamate signaling in the corticostriatal pathway, a crucial neural circuit for movement, reversing pathological changes in striatal neurons. Blocking this glutamate regulation negated EA's therapeutic effects. This study provides scientific support for the traditional East Asian medicine view of these acupoints as "Sea of Marrow" points linked to brain health and suggests that consistent EA treatment, particularly early on, could be valuable in PD management. Although human studies are needed, this research offers a promising avenue for acupuncture practitioners to consider when integrating EA into PD care.

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