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Doctors Making A Difference

Doctors Making A Difference

著者： Peter M. Crane MD
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Not every doctor dreams of climbing the traditional ladder. Some dream of building their own. Doctors Making a Difference, hosted by Dr. Peter Crane, tells the stories we rarely hear, of physicians who dared to ask, “Is this all there is?” and then changed their lives to answer it. These are the moments after burnout, after bureaucracy, after sacrifice. When purpose called louder than protocol. Each week, listeners meet doctors who stepped off the expected path—into roles as entrepreneurs, advocates, creatives, and leaders redefining what it means to heal. They didn’t just survive medicine. They made it theirs.Copyright 2025 Doctors Making A Difference 個人ファイナンス 個人的成功 経済学 自己啓発 衛生・健康的な生活 身体的病い・疾患
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  • Pickleball After Chemo: The Future of Cancer Treatment with Dr. Brandon Mancini | LMC #92

    Pickleball After Chemo: The Future of Cancer Treatment with Dr. Brandon Mancini | LMC #92
    2026/07/16
    This episode is sponsored by NURP NURP helps busy physicians grow their wealth through AI-powered algorithmic trading designed for demanding careers. No day trading, no guesswork, and no constant market watching required. Ready to put your money to work? Visit start.nurp.com/doctors to learn more. Trading involves risk, and results may vary. This is not financial advice. —----------------------------- In this episode of Living with Metastatic Cancer, Dr. Peter Crane (physician and SFT patient) interviews Dr. Brandon Mancini. They cover Dr. Mancini’s journey from traditional radiation oncology to leading theranostics at Banff Health, the science behind molecularly targeted radiopharmaceuticals, current FDA-approved treatments, ongoing clinical trials, and how this field offers hope with highly precise, well-tolerated therapies. The conversation highlights opportunities for patients with rare and common cancers, practical access to treatments, and the rapid evolution of the field. Episode Highlights Dr. Mancini’s personal motivation: influenced by his mother’s breast cancer journey and her work as a clinical trials research nurse in radiation oncologyCareer pivot from community radiation oncology to subspecializing in theranostics after training in GermanyExplanation of theranostics: pairing diagnostic and therapeutic radiotracers that target specific proteins on or around tumor cellsFDA-approved treatments for metastatic prostate cancer (Pluvicto) and neuroendocrine tumorsExciting targets like FAP (fibroblast activation protein) for pan-cancer “basket” trials, including sarcomas and SFTCombination therapies, alpha vs. beta emitters, dosing/scheduling innovations, and moving treatments earlier in the disease courseBanff Health’s comprehensive program, clinical trials across ~15 tumor types, and serving patients from 26 states and 2 countriesPatient experience: minimal side effects allowing normal activities soon after treatmentFuture outlook: more approvals, earlier use, broader targets, and reduced reliance on traditional chemotherapy Top 3 Takeaways Theranostics represents a new era of precision medicine, highly targeted radiopharmaceuticals attack cancer at the molecular level while sparing healthy tissue, often with excellent tolerability.Patients with rare cancers like solitary fibrous tumors can benefit from emerging FAP-targeted trials and should explore clinical trial options and specialized centers.The field is advancing rapidly: centralized expertise, more trials, and earlier intervention are expanding access and improving outcomes across many tumor types. About Dr. Brandon Mancini Dr. Brandon Mancini is a radiation oncologist and Medical Director at Banff Health in Grand Rapids, Michigan, one of the world’s leading centers for theranostics. After a decade in traditional radiation oncology, he trained in Germany and helped launch Banff Health’s program in 2022. He specializes in targeted radiopharmaceutical therapies and is deeply involved in clinical trials expanding this field. Connect with Dr. Brandon Mancini Banff Health: banffhealth.com About the Host: Dr. Peter Crane is a board-certified physician, educator, and storyteller with a heart for service and a calling to spotlight doctors who make a difference—in their communities, in medicine, and in the lives they touch. Through Doctors Making a Difference, he brings you into intimate conversations with physicians who have overcome challenges, redefined success, and found purpose in and beyond the clinic. His goal is simple: to help more doctors stay in medicine by showing them what's possible. About the Show: Doctors Making a Difference is more than a podcast—it’s a movement to highlight the good, the gritty, and the deeply human side of medicine. In every episode, Dr. Peter Crane interviews physicians whose stories defy the script. From burnout recovery to bold career pivots, health challenges to quiet leadership, this show honors the truth that healing begins with connection—and doctors, too, deserve to be whole. Visit: doctorsmakingadifference.com LMC Series Note: Living with Metastatic Cancer (LMC) explores the science, decisions, and day-to-day realities of life with advanced disease—through candid physician–patient conversation The Doctors Making a Difference Podcast is for informational purposes only and does not substitute for medical, legal, or professional advice. Always consult appropriate experts regarding your unique circumstances. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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    38 分
  • Algorithmic Trading, Financial Freedom & Alternatives for Busy Physicians With Jeff Sekinger | DMD#91

    Algorithmic Trading, Financial Freedom & Alternatives for Busy Physicians With Jeff Sekinger | DMD#91
    2026/07/09
    This episode is sponsored by NURP NURP helps busy physicians grow their wealth through AI-powered algorithmic trading designed for demanding careers. No day trading, no guesswork, and no constant market watching required. Ready to put your money to work? Visit start.nurp.com/doctors to learn more. Trading involves risk, and results may vary. This is not financial advice. —----------------------------- In this episode of Doctors Making a Difference, Dr. Peter Crane interviews Jeff Sekinger, founder of NURP (algorithmic trading software), Zero Percent (financial education), and Orca Capital (digital asset hedge fund). Jeff shares his journey from JPMorgan to entrepreneurship, the inspiration behind creating accessible quant strategies for non-accredited investors, and how NURP’s Midas strategy brings hedge fund-level tools to individual brokerage accounts. The conversation covers the challenges physicians face with time, financial education, and diversification; the power of positive expectancy strategies; market-neutral trading vs. traditional buy-and-hold; liquidity and autonomy in algorithmic trading; and realistic portfolio allocation (1-20%). Jeff emphasizes education, risk management, backtesting, and third-party verification while stressing that this is not financial advice and trading involves significant risk. Episode Highlights Jeff’s early investing lessons from his dad and transition from JPMorgan to founding three finance companiesThe gap between ultra-high-net-worth access (private equity, hedged products) and what most physicians can realistically getModern Portfolio Theory, the Efficient Frontier, and the role of uncorrelated alternativesWhy most day traders lose money and how algorithmic software removes emotion, timing, and execution errorsMidas strategy: Gold-focused, backtested 15+ years, live 16-month track record with strong outperformanceInvestor autonomy, keep capital in your own brokerage, full liquidity, adjustable risk settings, equity protectionMarket-neutral exposure: Strategy sits in cash and only trades on high-probability setupsCommon physician investing pitfalls and the value of diversification beyond 401(k)s and index fundsDemo/trial option for physicians to test the strategy risk-free before committing capitalTransparency through MyFXBook verification and Alpha Performance Services Top 3 Takeaways Financial independence gives physicians the freedom to pursue mission-driven work, lack of it quietly limits options.Algorithmic trading can provide uncorrelated, market-neutral exposure with positive expectancy, but it still carries real risk of loss and belongs as a small, diversified portion (1-20%) of a broader portfolio.Busy professionals benefit from tools that remove emotion and manual execution, education, backtesting, liquidity, and personal control are essential when exploring alternatives. About the Guest Jeff Sekinger is the founder of NURP, Zero Percent, and Orca Capital. With experience at JPMorgan in asset management, he builds financial education tools and algorithmic trading strategies designed to give higher-net-worth individuals (including many medical professionals) access to sophisticated, quantitative approaches in their own brokerage accounts. Connect with Jeff Sekinger Website: start.nurp.com/doctors Learn more and try the demo at nurp.com About the Host: Dr. Peter Crane is a board-certified physician, educator, and storyteller with a heart for service and a calling to spotlight doctors who make a difference—in their communities, in medicine, and in the lives they touch. Through Doctors Making a Difference, he brings you into intimate conversations with physicians who have overcome challenges, redefined success, and found purpose in and beyond the clinic. His goal is simple: to help more doctors stay in medicine by showing them what's possible. About the Show: Doctors Making a Difference is more than a podcast—it’s a movement to highlight the good, the gritty, and the deeply human side of medicine. In every episode, Dr. Peter Crane interviews physicians whose stories defy the script. From burnout recovery to bold career pivots, health challenges to quiet leadership, this show honors the truth that healing begins with connection—and doctors, too, deserve to be whole. Visit: doctorsmakingadifference.com LMC Series Note: Living with Metastatic Cancer (LMC) explores the science, decisions, and day-to-day realities of life with advanced disease—through candid physician–patient conversations. The Doctors Making a Difference Podcast is for informational purposes only and does not substitute for medical, legal, or professional advice. Always consult appropriate experts regarding your unique circumstances. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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    40 分
  • Bariatric Surgery Versus GLP-1s: The Real Talk on Weight Loss That Works | Dr. Alexa Roth | DMD#90

    Bariatric Surgery Versus GLP-1s: The Real Talk on Weight Loss That Works | Dr. Alexa Roth | DMD#90
    2026/07/02
    This episode is sponsored by NURP NURP helps busy physicians grow their wealth through AI-powered algorithmic trading designed for demanding careers. No day trading, no guesswork, and no constant market watching required. Ready to put your money to work? Visit start.nurp.com/doctors to learn more. Trading involves risk, and results may vary. This is not financial advice. —----------------------------- In this episode of Doctors Making a Difference, Dr. Peter Crane interviews Dr. Alexa Roth, a bariatric surgeon and obesity medicine specialist running a Center of Excellence program in Idaho. Dr. Roth discusses her path from competitive athlete and reluctant surgery student to falling in love with bariatric surgery, the psychological aspects of weight management, and how to approach patients with empathy and evidence-based options. They explore the strengths and limitations of lifestyle changes, GLP-1 medications, and surgical interventions, cost comparisons, insurance challenges, medical tourism risks, and early intervention in pediatric obesity. Dr. Roth also shares insights on public education through social media and her website. Episode Highlights From competitive athlete and internal medicine leanings to discovering a passion for surgery during a long Nissen redo caseWhy bariatric surgery offers uniquely rewarding long-term patient relationships and near-100% satisfactionThe combination of technical laparoscopic skill, psychology/psychiatry overlap, and life-changing outcomes that drew her to the fieldPatient-centered approach: Meeting patients where they are, understanding their story, and avoiding shame/blame messagingSpectrum of treatments, lifestyle (5-7% TBWL), medications (up to ~22%), and surgery (20-40%+ TBWL), and how to match them to patient goalsGLP-1 revolution making obesity more approachable and increasing patient willingness to seek careCost comparison: Bariatric surgery often pays for itself in under a year vs. ongoing brand GLP-1 costs; long-term savings for the healthcare systemRisks of medical tourism (lack of follow-up, complications, nutritional issues) and the importance of comprehensive lifelong supportEarly intervention in children and adolescents; family-wide benefits when adults pursue treatmentUsing authentic, short-form social media content to combat misinformation and educate the public Top 3 Takeaways Obesity is a chronic disease driven by genetics, epigenetics, and environment. Treat it with the same nuance and tools (lifestyle + meds + surgery) as diabetes or hypertension, not just “eat less and move more.”The best treatment is the one the patient will actually stick with; shared decision-making using realistic expectations on efficacy, cost, and lifelong commitment leads to better adherence.Surgery and medications are complementary tools, not competitors. Comprehensive programs that offer all options deliver superior, sustainable results and change entire families. About Dr. Alexa Roth Dr. Alexa Roth is a board-certified bariatric surgeon and obesity medicine specialist in Idaho. She leads a comprehensive weight management program recognized as a Center of Excellence. A former competitive swimmer and triathlete, she brings discipline and empathy to her practice. She is passionate about patient education, reducing stigma around obesity, and using social media to share evidence-based information. Website: www.drrothweightloss.com Instagram: @drrothweightloss Dr. Peter Crane is a board-certified physician, educator, and storyteller with a heart for service and a calling to spotlight doctors who make a difference—in their communities, in medicine, and in the lives they touch. Through Doctors Making a Difference, he brings you into intimate conversations with physicians who have overcome challenges, redefined success, and found purpose in and beyond the clinic. His goal is simple: to help more doctors stay in medicine by showing them what's possible. About the Show: Doctors Making a Difference is more than a podcast—it’s a movement to highlight the good, the gritty, and the deeply human side of medicine. In every episode, Dr. Peter Crane interviews physicians whose stories defy the script. From burnout recovery to bold career pivots, health challenges to quiet leadership, this show honors the truth that healing begins with connection—and doctors, too, deserve to be whole. Visit: doctorsmakingadifference.com LMC Series Note: Living with Metastatic Cancer (LMC) explores the science, decisions, and day-to-day realities of life with advanced disease—through candid physician–patient conversations. The Doctors Making a Difference Podcast is for informational purposes only and does not substitute for medical, legal, or professional advice. Always consult appropriate experts regarding your unique circumstances. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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    39 分
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