Cyclodextrin in biologic formulation
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Cyclodextrin in biologic formulation
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🎙️ New Episode Alert – Carbohydrate Chronicles, S2E2
In this episode of Carbohydrate Chronicles, we’re diving deep into the world of cyclodextrins (CDs) and their fascinating potential in biological drug formulations. From stabilizing delicate protein therapeutics to boosting vaccine efficacy and breaking new ground in gene therapy, CDs are proving to be far more than just sugar rings. We unpack how their unique structure allows for molecular encapsulation—enhancing solubility, stability, and delivery while minimizing side effects. Whether you're in drug development or just love cutting-edge biotech, this masterclass offers a fresh look at how CDs are redefining the biologics space.
We also explore real-world applications and challenges: Why haven't CD-based monoclonal antibodies reached the market yet? How do CDs stack up against polysorbates, and what makes them ideal cryoprotectants in vaccines? Plus, get a sneak peek at CarboHyde’s pioneering research into CD-based gene delivery systems that could rival lipid nanoparticles in efficiency and safety. Tune in to discover how these versatile molecules are quietly reshaping the future of pharmaceutical formulations.