In this excerpt from Tall Rounds®, Gianluca Torregrossa, MD, discusses minimally invasive and totally endoscopic coronary artery bypass grafting (TECAB), highlighting procedural advances that enable multi-vessel revascularization through less invasive approaches.

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View the full Tall Rounds program. https://2207941.mediaspace.kaltura.com/category/Tall+Rounds/75663251

Steven Nissen, MD, and Luke Laffin, MD, discuss one-year follow-up data for CTX310, a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3 to treat lipid disorders. They review the sustained reductions in LDL cholesterol and triglycerides, and the potential role of one-time gene-editing therapies in cardiovascular prevention and lipid management.

Read the article. https://consultqd.clevelandclinic.org/effects-of-crispr-cas9-gene-editing-for-dyslipidemia-endure-1-year

Steven Nissen, MD, and Ashish Sarraju, MD, discuss early clinical data on Kylo-11, a novel therapy that produced substantial reductions in lipoprotein(a) for up to one year after a single injection. Lowering lipoprotein(a), a genetically determined cardiovascular risk factor linked to atherosclerotic disease and aortic stenosis, remains an important focus for preventive cardiology. Learn about the new drug's mechanism and safety findings.

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Marc Gillinov, MD, and Per Wierup, MD, discuss the evolution of robotic valve surgery, including advanced mitral valve repair techniques, patient selection and expanding applications for aortic valve and coronary procedures. They examine how enhanced visualization, instrument dexterity and a mature robotic program support excellent safety, durability and clinical outcomes.

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Bo Xu, MD, and Shinya Unai, MD, discuss approaches to diagnosing and treating infective endocarditis, including indications for surgical intervention. The conversation highlights the role of multimodality imaging , individualized surgical planning and multidisciplinary care strategies to improve patient outcomes.

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Donna Kimmaliardjuk, MD, and Gianluca Torregrossa, MD, discuss the expanding role of robotic coronary artery bypass grafting, including total endoscopic coronary artery bypass (TECAB). They explore how a tailored surgical approach can improve long-term patient outcomes.

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Faisal Bakaeen, MD, and Grant Reed, MD, discuss recent advances in the treatment of coronary artery disease, including drug-coated balloons, intravascular imaging, calcium modification and evolving PCI strategies. They also examine innovations in coronary artery bypass grafting, multi-arterial revascularization, minimally invasive and robotic techniques and the growing role of heart team collaboration in selecting surgical, percutaneous and hybrid treatment approaches.

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Luke J. Laffin, MD, and Vikas Sunder, MD, discuss the evolving role of aspirin in primary prevention, emphasizing individualized assessment of each patient's cardiovascular and bleeding risk. They explore how coronary artery calcium scores, lipoprotein(a) levels and comorbid conditions factor into aspirin recommendations in contemporary preventive cardiology practice.

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.