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  • What Stress, Burnout, and Hustle Culture Do To Your Body

    What Stress, Burnout, and Hustle Culture Do To Your Body
    2025/07/31
    Had I protected my body and brain, I’d be wealthier and more successful today. Culture is lying to you — you do not need to martyr yourself to be successful. Here’s how you can avoid making the same mistake I did. Study Links: Burnout + Heart Attack Risk Hours Worked + Heart Disease Sleep Deprivation in CEOs Sleep Deprivation in Judges Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Chapters: 00:00 - Introduction 03:11 - Martyring Yourself for Success 15:50 - Study: ‘Overwork Will Kill You’ 20:04 - Sleep + Decision Making (Studies) 25:54 - Physical Fitness + Diet (Studies) 28:24 - Treating Health Like Religion 33:30 - Tips for Balancing Work and Health 43:58 - Resting Heart Rate Before Bed 47:06 - Protecting Your Agency
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    52 分
  • These Toxins Are Silently Ruining Your Health

    These Toxins Are Silently Ruining Your Health
    2025/07/24
    Society is bathing us in chemicals. From wildfires to 4th of July fireworks, toxins feel inescapable. Here’s what I’m doing to limit exposure and reduce my levels. Show Links: Blueprint Food Guide: https://blueprint.bryanjohnson.com/pages/blueprint-protocol#food-guide Further Listening: “How Sauna Detoxified My Body” - Bryan Johnson Podcast “We Need to Talk About Microplastics” - Bryan Johnson Podcast Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Chapters: 00:00 - Introduction 01:20 - Fireworks + Toxic Celebrations 12:27 - LA Wildfire Toxins 16:57 - Truth About Air Quality 21:23 - PFAS 31:49 - Reducing Toxins/PFAS 46:11 - Sauna, HBOT & Diet 50:13 - Don’t Freak Out
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    53 分
  • How to Travel Without Wrecking Your Sleep and Brain

    How to Travel Without Wrecking Your Sleep and Brain
    2025/07/17
    International travel is brutal on your mind, body, and sleep. We discuss the recent data and I share my current jet lag protocol (still evolving) to help minimize the damage after long flights. Study Links: Olympic Athletes + Jet Lag: https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.998484/full Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Chapters: 00:00 - Introduction 01:08 - Where’s Kate? 02:00 - Bryan’s Travel Experiment 03:44 - Debunking the ‘CEO Lifestyle’ 06:28 - Why Jet Lag Happens 08:00 - Jet Lag Recovery 14:00 - Improving Sleep 17:07 - Is Fighting Jet Lag Possible? 21:44 - Olympic Athlete Study 24:42 - Travel Rule of Thumb 33:55 - Shifting Your Mindset 35:10 - Setting Limits for Travel 44:25 - Jet Lag Protocol 50:41 - Stimulants During Travel 52:04 - Cryotherapy/Cold Therapy 53:00 - Episode Takeaways
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    59 分
  • We Need to Talk About Microplastics

    We Need to Talk About Microplastics
    2025/07/10
    Microplastics are everywhere — even in glass bottles. Should you be worried? Kate, Mike, and I interpret the data to understand the risk. I’ll share how I reduced my own levels by 93% so you can too. Study Links: Glass Bottle Study: https://www.sciencedirect.com/science/article/pii/S0889157525005344 Impact on Children: https://www.nejm.org/doi/abs/10.1056/NEJMms2409092 Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ CHAPTERS 00:00 - Introduction 01:27 - No Cause for Alarm (Yet) 02:05 - Microplastics Nuance 04:04 - What Are Microplastics? 05:24 - Science Is Still Emerging 07:39 - Microplastics in Our Bodies 09:51 - Study: Microplastics in Glass Bottles 11:42 - What Can We Trust? 12:53 - Building a ‘Don’t Die’ Society 14:23 - Microplastics in IV Drips 17:11 - Impact on Kids 18:47 - Microplastics in Washing Machines 19:31 - What is ‘Don’t Die’ 21:05 - Bryan’s Microplastics Measurements 22:36 - Total Plasma Exchange / Blood Donation 24:28 - The Water Bottle Dilemma 27:50 - Water Systems / Reverse Osmosis 28:36 - Reducing Microplastic Intake 32:05 - An 80/20 Approach 33:10 - Sauna and Microplastics 35:38 - A Challenge for Humanity 36:15 - Testing Microplastics at Home 37:54 - Bryan’s Upcoming Microplastics Tests 39:03 - Don’t Die Party 39:31 - Teaching Congress to Sleep
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    41 分
  • Advanced Guide to Better Sleep

    Advanced Guide to Better Sleep
    2025/07/03
    Quality sleep is the highest-return investment I’ve ever made. In this episode we walk you through my exact protocol, so you can cherry-pick what works, experiment, and track gains for yourself. Study Links: https://pmc.ncbi.nlm.nih.gov/articles/PMC3902870/ Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Chapters 00:00 – What Ruins Your Sleep Most? 01:50 – Sleep in Vegas: A Cautionary Tale 03:45 – How Important Is Sleep? 05:30 – Sleep Deprivation 07:20 – Kernel Willpower Study 09:20 – The 80/20 Of Sleep 10:10 – Being a Professional Sleeper 13:00 – Resting Heart Rate 19:00 – Psychology of Tracking Sleep 22:30 – Heart Rate (Before vs. During Sleep) 25:00 – Wearables 30:00 – Food as the #1 Sleep Killer 33:40 – 10 Rules for Perfect Sleep 44:30 – Bonus Tips 49:00 – Sleep Alone? 51:20 – Sleep + Mental Health 52:40 – Bryan’s Final Plea: Learn to Sleep
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    55 分
  • How Sauna Detoxified My Body

    How Sauna Detoxified My Body
    2025/06/26
    At last, we tested sauna for longevity. I’m dropping my sauna protocol and explaining why they are definitely worth the hype. Plus, hear about my first time ever stepping into one, and why it was one of the most difficult — but rewarding — protocols I’ve ever done. Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Chapters 00:00 – First Impressions of Sauna 01:30 – Assessing the Sweat Response in Kate and Bryan 03:00 – Why Sauna? The Science Behind the Heat 05:20 – How Sauna Mimics Exercise 08:30 – Early Biomarker Changes with Sauna 12:00 – Protocol Design & Measurement Strategy 15:30 – Bryan’s Difficulties Starting the Sauna Protocol 18:00 – Why Bryan Ices His Testicles in the Sauna 21:00 – Electrolyte Loss & Cramping 24:30 – Dry vs. Wet Sauna 27:00 – Practical Home Sauna Protocol 30:00 – Groups Who Shouldn’t Use Sauna 33:00 – Unexpected Effects of Sauna and Areas to Explore 38:00 – Skin Exposure & Sauna Material Safety 42:30 – Sauna Hygiene & Post-Sweat Protocol 45:00 – Measuring Sweat Toxins 47:30 – Kate and Bryan’s Personal Sauna Habits 49:00 – Sun Damage and Skin Aging with Teens 54:00 – Protocol as Part of a Broader Mission
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    55 分
  • The Dark Side of Fame, Money & High Performance With Dr. Mike Israetel

    The Dark Side of Fame, Money & High Performance With Dr. Mike Israetel
    2025/06/25
    Dr. Mike Israetel is back. We’re talking about deep work, sharing a brain with AI, strategies for creativity, and how money and fame changed our lives, for better and worse. About Dr. Mike: Dr. Mike Israetel is an expert in the field of fitness and performance. He’s served as a professor at Lehman College, Temple University, and the University of Central Missouri, teaching exercise science courses focusing on nutrition, strength, and hypertrophy. Learn more at: http://rpstrength.com/mike Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Chapters 0:00:00 - Deep Work 0:01:22 - Why Bryan Quit Flying 0:03:36 - Flow States 0:06:03 - ChatGPT & Edibles 0:08:49 - Dr. Mike’s Creative Process 0:14:36 - Everyone’s Creative Triggers 0:20:09 - Messaging Overload 0:25:28 - Fame & Money 0:34:00 - Does Money Make You Happier? 0:39:01 - Fame vs Fortune 0:50:23 - Cancel Culture 0:57:02 - Gratitude, & Identity 1:03:02 - Friendship & Fame
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    1 時間 7 分
  • How I Became The World's Healthiest Human

    How I Became The World's Healthiest Human
    2025/06/24
    I’ve become the worlds healthiest human. Today I’m sharing more on my longevity protocols and biomarker testing and why that’s an essential piece of the Don’t Die movement. We’re also getting into sperm health and why it’s important to keep your testicles cool. Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Chapters 0:00:00 - Today's Topics 0:04:45 - 1: The Decline of Global Sperm Health 0:08:45 - 2: Bryan’s Metrics and Above-Average Results 0:15:00 - 3: Sperm Health Reveals What?!? 0:19:20 - 4: Sauna, Ice, and Testicle Cooling 0:24:15 - 5: How to Improve Sperm Health 0:30:10 - 6: What Bryan’s Markers Actually Prove 0:35:30 - 7: A Deep Dive into Bryan’s Full Biomarker Testing 0:41:00 - 8: Oral Health, Attachment Loss, and Gum Therapy 0:47:00 - 9: What does 'Most Measured Human' mean? 0:53:30 - 10: Aging Speed, Inflammation, Testosterone 1:07:00 - 11: Where Bryan’s Protocol Needs Improvement 1:12:40 - 12: Viewer Feedback, & The Future of the Podcast
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    50 分