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  • H5N1 Bird Flu Surges Globally: US Leads with 689 Outbreaks, Human Cases Rise in Multiple Countries
    2025/12/24
    Welcome to Avian Flu Watch: Global H5N1 Tracker. Im monitoring the worldwide spread of highly pathogenic avian influenza A(H5N1) bird flu, drawing on the latest data from WHO, ECDC, FAO, and PAHO as of late November 2025.

    Current hotspots reveal intense activity. In the Americas, the United States leads with 689 H5N1 outbreaks in poultry, wild birds like mallards and Canada geese, and mammals including polar bears and skunks since October, per FAO reports. PAHO notes 508 outbreaks across nine countries in 2025, driven by wild birds along migration routes from North to South America. Canada reports 53 events in poultry and wild species like bald eagles. In Europe, Germany dominates with 1176 detections in poultry and wild birds such as greylag geese, followed by France at 155 and the UK at 308, according to ECDC and FAO. Asia sees outbreaks in Japan with 43 in chickens, South Korea with 15, and the Philippines with three in ducks.

    Visualize surging trend lines: FAO data shows 1738 global outbreaks since October across 41 countries, a sharp rise from prior months, with Americas and Europe comprising over 80 percent. Comparative stats highlight US cases dwarfing others, with 415 new events versus Europes scattered poultry hits. Human infections remain low: 22 cases from December 2024 to March 2025 in the US, Cambodia, UK, and China, per PMC, plus 19 more September to November including two deaths in Cambodia and one fatal US H5N5 case, ECDC states. Cumulative US human H5 cases hit 71 since 2024, WHO confirms.

    Cross-border transmission patterns follow wild bird migrations. Phylogeographic analysis in South America traces H5N1 from North American birds via Pacific coasts to Argentina, Uruguay, and Brazil, with dual routes: avian from Argentina and pinniped-derived from Chile, per a Uruguay study. A 2025 Argentine reassortment event acquired segments from local low-path viruses, raising adaptation concerns. In Europe, central and southeastern detections link to migratory waterfowl.

    Containment shines in targeted culls: US backyard flock depopulation resolved a Texas outbreak by December 1, BEACON reports. Failures persist in wild reservoirs, evading vaccines, fueling mammal spills like Australian elephant seals.

    Emerging variants of concern include H5N5, first human case globally in the US November 2025, and South American reassortants with PB2 adaptations for mammals. No sustained human-to-human spread, but One Health surveillance is critical.

    Travel advisories: CDC and WHO urge avoiding sick birds, unpasteurized dairyall FDA-tested products negative for viable virusand poultry markets in hotspots like the US, Europe, and Asia. Practice hand hygiene; no broad restrictions yet.

    Thanks for tuning in. Come back next week for more. This has been a Quiet Please production. For me, check out Quiet Please Dot A I.

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    3 分
  • H5N1 Avian Flu Spreads Globally: Unprecedented Outbreak Affects Multiple Continents with Rising Transmission Rates
    2025/12/22
    AVIAN FLU WATCH: GLOBAL H5N1 TRACKER

    Welcome to Avian Flu Watch, your weekly briefing on the worldwide spread of H5N1. I'm your host, and today we're diving into the latest data on this rapidly evolving pandemic in animals.

    Let's start with the geographic hotspots. As of late November 2025, the situation report from the Food and Agriculture Organization shows staggering numbers across multiple continents. Europe remains the epicenter, with Germany reporting 1,176 total events since October, followed by France with 155 events and the United Kingdom with 308 events. The United States dominates the Americas with 689 confirmed outbreaks since October, affecting everything from wild waterfowl to dairy herds. In Asia, Japan has reported 47 events across poultry and wild birds, while Bangladesh and South Korea continue documenting cases.

    The trend lines tell a concerning story. According to the ECDC, between September and November 2025, H5N1 demonstrated persistent circulation across temperate zones heading into winter months. The World Health Organization notes that since 2003, over 890 human infections have been confirmed globally, with roughly 476 deaths recorded by September 2025. What's critical here is that human cases remain sporadic. Between September and November 2025, only 19 human infections were reported across four countries: Cambodia, China, Mexico, and the United States.

    Now let's examine cross-border transmission patterns. Research from the Pan American Health Organization reveals that H5N1 reached South America through migratory birds from North America, initially spreading along Pacific coasts before advancing into Atlantic-bordering nations. The virus has established two distinct transmission routes in Uruguay: one driven by wild birds and poultry from Argentina, and another associated with marine mammals originating from Chile. This demonstrates the virus's remarkable ability to exploit multiple ecological pathways simultaneously.

    Notably, a reassortment event occurred in Argentina during 2025, where H5N1 acquired four genetic segments from a locally circulating low pathogenicity influenza virus. This genetic acquisition represents a critical concern for pandemic preparedness, as reassortment events can enhance transmissibility and virulence.

    Regarding containment outcomes, we've seen mixed results. The United Kingdom and Germany implemented aggressive surveillance and culling protocols that have contained outbreaks to specific regions, though numbers remain elevated. Conversely, the United States struggles with continuous reintroduction through wild bird populations, making eradication essentially impossible. Belgium's poultry sector reported 76 confirmed events by late November despite culling measures.

    The emerging variant of concern is the H5N1 2.3.4.4b clade, now dominant across the Americas and Europe. The Nature journal documents that this lineage has spread globally since 1996, establishing enzootic transmission in multiple wildlife reservoirs. Additionally, H5N2 emerged in Mexico, and H5N5 caused a fatal human case in the United States, highlighting the virus's capacity for genetic evolution.

    For travel and exposure recommendations, health authorities advise avoiding direct contact with wild birds, particularly waterfowl and raptors showing signs of illness. Poultry farmers should implement strict biosecurity measures. Healthcare workers in affected regions should maintain respiratory precautions when handling avian specimens.

    The bottom line: H5N1 has transitioned from sporadic outbreak to endemic circulation across multiple continents. Wildlife migration patterns will continue driving spread into 2026, making coordinated international surveillance absolutely essential.

    Thank you for joining Avian Flu Watch. Tune in next week for updated case counts and emerging transmission data. This has been a Quiet Please production. For more information, check out Quiet Please dot A I.

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    4 分
  • Global H5N1 Bird Flu Surge Raises Alarm Across Continents as Virus Spreads Through Wildlife and Threatens Livestock
    2025/12/19
    This is “Avian Flu Watch: Global H5N1 Tracker.”Today’s data show H5N1 remains entrenched in birds across multiple continents, with growing concern about mammals and rare human cases. According to the CDC, H5 bird flu is now widespread in wild birds worldwide, driving repeated outbreaks in poultry and spillover into U.S. dairy cattle and sporadic human infections. The dominant strain is clade 2.3.4.4b, described by CIDRAP as responsible for unprecedented deaths in wild birds and poultry across Africa, Asia, Europe, and the Americas.Let’s start with the geographic hotspots.The UN Food and Agriculture Organization reports more than 1,700 highly pathogenic avian influenza outbreaks in animals since October, spanning over 40 countries. Europe is a major hotspot: Germany alone has reported more than 1,100 H5 and H5N1 events this season, with France, the Netherlands, Spain, and the United Kingdom also logging dozens to hundreds of outbreaks, mainly in poultry and migratory waterfowl. In North America, U.S. surveillance from USDA and CDC shows detections in wild birds in nearly every state, recurring poultry outbreaks, and infections in mammals ranging from foxes and skunks to polar bears. Canada reports multiple poultry and wild bird events, especially in Atlantic and prairie provinces. In South America, research summarized in Frontiers and other journals traces rapid spread along both Pacific and Atlantic coasts, with major mortality in seabirds and marine mammals in Chile, Peru, Argentina, Uruguay, and Brazil.Picture the trend lines as three stacked graphs. The first, poultry outbreaks, shows a steep climb from 2021 through 2023, a brief dip, then a renewed rise in 2025, especially in Europe and the Americas. The second, wild bird detections, is a broad, high plateau, reflecting persistent global circulation. The third, mammal cases, is lower but clearly trending upward, with well over 200 mammalian species now affected, according to Infection Control Today. A fourth, much smaller line for human infections remains close to zero, but each dot represents a serious, high-fatality event, with the World Health Organization counting about 1,000 human H5N1 cases since 2003.Cross‑border transmission is driven primarily by wild bird migration. A major Nature study on the North American epizootic shows that migratory waterfowl were central to moving H5N1 from Eurasia into North America and then across the continent, linking Arctic breeding grounds with coastal and inland flyways. A geospatial analysis in AGU journals maps corridors where bird migration, wetlands, and dense poultry production overlap, identifying high‑risk “bridges” between continents and regions. In South America, phylogeographic work in Uruguay shows two converging routes: one lineage moving via wild birds and poultry from Argentina and Brazil, and another associated with marine mammals arriving from Chile.Containment successes include rapid culling and zoning in several European countries and in the United Kingdom, where the government imposes three‑kilometer protection zones and ten‑kilometer surveillance zones around new outbreaks in commercial flocks. In North America, aggressive depopulation of infected poultry operations and tighter farm biosecurity have limited some secondary spread. Failures are equally clear: repeated re‑introductions from wild birds, explosive outbreaks in densely populated poultry regions, and large‑scale spillover to marine mammals show that national efforts often lag behind the virus’s transboundary movement.On variants, laboratories tracked by WHO and CIDRAP are closely monitoring clade 2.3.4.4b for mutations that enhance mammalian adaptation, especially in the PB2 gene. A reassortant H5N1 detected in Argentina in 2025, which acquired several internal genes from local low‑pathogenic strains, underscores the virus’s capacity to evolve in real time.Current travel advisories do not restrict general international travel, but public health agencies recommend staying away from live bird markets, avoiding contact with sick or dead birds and marine mammals, not entering poultry barns or backyard coops without permission and proper protection, and following national guidance on consumption of properly cooked poultry, eggs, and dairy. People with occupational exposure to birds or cattle should use personal protective equipment and report respiratory or flu‑like illness promptly.Thanks for tuning in to “Avian Flu Watch: Global H5N1 Tracker.” Come back next week for more data‑driven updates. This has been a Quiet Please production, and for more from me, check out QuietPlease dot A I.For more http://www.quietplease.aiGet the best deals https://amzn.to/3ODvOtaThis content was created in partnership and with the help of Artificial Intelligence AI
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    5 分
  • H5N1 Avian Flu Spreads Globally: 175 Million Poultry Culled, Human Cases Rise Amid Ongoing Pandemic Threat
    2025/12/17
    Avian Flu Watch: Global H5N1 Tracker

    Welcome to Avian Flu Watch: Global H5N1 Tracker, your data-driven update on the worldwide spread of highly pathogenic avian influenza. Im here to break down the latest numbers, trends, and risks as of mid-December 2025.

    Starting with geographic hotspots. In the US, H5N1 has hit all 50 states, with over 175 million poultry depopulated since early 2025, per Infection Control Today reports. Northern Indiana drives ongoing losses, while Washington state confirmed the first fatal human H5N5 case in a backyard flock owner with comorbidities—no human-to-human spread detected, according to Lanvira Flock Watch. Dairy cows remain a concern, with clades B3.13 and D1.1 showing enhanced mammal infectivity.

    Europe is in crisis mode. The European Commission logs 577 poultry outbreaks in 2025, surpassing 2023 and 2024 totals, with France hitting 68 since October—nearly 800,000 birds affected, even in vaccinated duck flocks. Germany leads wild bird cases at over 2,800 yearly, plus 460 new ones. The UK reports multiple large commercial outbreaks in December alone: three in England (Kent, Lincolnshire, Norfolk), culling thousands, via GOV.UK updates.

    Asia sees resurgent activity. Japan tallied six broiler outbreaks since mid-October, culling 48,000 and 75,000 birds. South Korea hit six laying hen cases, including 130,000 birds. India’s Uttarakhand confirmed five flocks over 21,000 birds; Iraq one after a month gap. China disclosed four unreported pediatric H9N2 cases in October, Lanvira notes.

    Africa reemerges: Nigeria’s clustered backyard losses post-five-month silence; South Africa’s Western Cape outbreak killed 150,000 on one farm plus 40 wild birds, per WOAH via Lanvira.

    South America’s H5N1 2.3.4.4b clade persists via migratory birds, with phylogroups showing avian-to-poultry and pinniped-to-bird routes. A 2025 Argentine reassortment acquired mammal-adaptive PB2 mutations (Q591K, D701N), spreading to Uruguay, Brazil, and the Falklands, PMC analysis reveals.

    Visualize the trends: Upward trend lines in Europe spike post-summer, with 90 new poultry outbreaks in one week. US poultry losses plateau but mammal cases rise—over 200 species affected globally. Comparative stats: 2025 European detections dwarf priors; Americas report from 67 to 81 countries since 2022, CIDRAP warns.

    Cross-border patterns scream wild bird migration: Pacific-to-Atlantic spread in South America; clade 2.3.4.4b from Eurasia via birds to Americas. Limited containment wins include UK rapid culls resolving zones quickly, but failures abound—vaccinated French flocks infected, summer lulls masking persistence.

    Emerging variants: H5N5 in US humans and Scottish birds; mammal-adapted strains in dairy; fever-resistant H5N1 per new studies. Global groups flag clade 2.3.4.4b’s mammal surge as human threat.

    Travel advisories: CDC urges avoiding sick birds, unpasteurized dairy; WHO monitors H5N5. Boost biosecurity, report wild bird die-offs.

    Thanks for tuning in to Avian Flu Watch. Join us next week for more. This has been a Quiet Please production—for me, check out Quiet Please Dot AI. Stay vigilant.

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    5 分
  • Global H5N1 Outbreak Intensifies: Millions of Birds Affected Across 38 Countries with Rising Transmission Risks
    2025/12/15
    Avian Flu Watch: Global H5N1 TrackerThis week, we are tracking a highly dynamic H5N1 landscape, with new animal and occasional human infections reshaping global risk.Globally, the UN Food and Agriculture Organization reports nearly one thousand H5N1 and related highly pathogenic avian influenza outbreaks in animals across 38 countries since late September, affecting millions of birds in commercial and backyard settings. The virus remains entrenched in wild bird reservoirs on every continent except Antarctica, sustaining a steady baseline of transmission.Geographically, three hotspots stand out. In Europe, the European Commission and the European Centre for Disease Prevention and Control describe a sharp uptick in H5N1, with more than 500 poultry farm detections so far this year and over 2,800 wild bird cases, concentrated in France, Germany, the United Kingdom, and the Iberian Peninsula. In North America, the US Department of Agriculture has confirmed H5N1 in commercial and backyard flocks in dozens of states over the last month, totaling more than 4 million birds culled, while wild bird positives continue along the Atlantic and Mississippi flyways. In Asia and Africa, Lanvira’s Flock Watch reports new H5N1 outbreaks in India, Iraq, Nigeria, and South Africa, including single farms holding more than 150,000 birds.Imagine a global line chart: on the x axis, the last 12 months; on the y axis, weekly H5N1 detections in animals. We see a winter 2024–25 peak, a summer trough, and now a renewed climb approaching or surpassing last season’s highs in Europe and North America. A companion bar chart, broken down by region, shows Europe leading in poultry cases, North America in wild bird and mixed-species detections, and South America plateauing after its first explosive wave.Cross-border transmission is driven largely by migratory birds. A Nature analysis of the North American epizootic shows wild birds as the central vectors linking outbreaks across flyways, while a recent South American phylogeographic study demonstrates H5N1 moving from Chile and Argentina into Uruguay and Brazil via seabirds and marine mammals, then back into inland poultry. These data highlight how virus lineages hop seamlessly between countries and host species, challenging traditional border-based control.There have been notable containment successes. The United Kingdom’s animal health authorities continue to rapidly impose 3 kilometer protection and 10 kilometer surveillance zones around each new farm detection, with targeted culling that has ended several regional outbreaks. In the United States, aggressive depopulation and enhanced biosecurity have stopped spread beyond affected dairy herds and poultry premises in multiple states.But there are also failures. According to Infection Control Today, H5N1 has now impacted poultry in all 50 US states, requiring the loss of more than 175 million birds since the start of the epizootic, underscoring gaps in farm-level biosecurity and wildlife interface control. In Africa, reports of repeated large flock losses in Nigeria and South Africa point to persistent vulnerabilities in early detection and compensation systems.Genetically, the World Organisation for Animal Health and academic studies describe continued evolution within clade 2.3.4.4b, including a 2025 reassortant in Argentina that acquired four gene segments from local low-pathogenic viruses. Separate analyses document mammal-adaptive mutations in polymerase genes in South American marine mammals and some poultry, reinforcing concern about incremental gains in mammalian fitness. In parallel, the World Health Organization recently reported the first fatal human H5N5 infection in the United States, likely linked to backyard poultry exposure, although no sustained human-to-human spread has been detected.For travelers, public health agencies, including the CDC and ECDC, advise avoiding live bird markets and poultry farms, steering clear of sick or dead wild birds and marine mammals, and following local notices on animal movement and hunting. Travelers working with animals should use personal protective equipment, maintain strict hand hygiene, and ensure seasonal influenza vaccination, which reduces co-infection risk even though it does not protect against H5N1 itself.You’ve been listening to “Avian Flu Watch: Global H5N1 Tracker.” Thank you for tuning in, and come back next week for more data-driven surveillance from around the world. This has been a Quiet Please production, and for more from me, check out QuietPlease dot A I.For more http://www.quietplease.aiGet the best deals https://amzn.to/3ODvOtaThis content was created in partnership and with the help of Artificial Intelligence AI
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    5 分
  • H5N1 Avian Flu Surges Globally: 175 Million Birds Lost, Human Cases Rise, Experts Warn of Expanding Pandemic Risk
    2025/12/13
    Avian Flu Watch: Global H5N1 Tracker

    Welcome to Avian Flu Watch: Global H5N1 Tracker, your data-driven update on the worldwide spread of highly pathogenic avian influenza. Im here with the latest from Lanviras Flock Watch bi-weekly report as of December 5, 2025, PAHO, WOAH, and regional surveillance.

    Geographic hotspots dominate the picture. In the US, poultry losses exceed 175 million birds across all 50 states per Infection Control Today, with northern Indiana driving sustained activity. A fatal H5N5 human case in Washington state marks the first for this strain, linked to backyard flocks with wild bird exposure; no human-to-human spread detected. Europes 2025 totals surpass prior years, with 577 poultry outbreaks in 13 countries per European Commission data cited in Flock Watchnearly 90 new ones in late November alone. France reports 68 outbreaks since October, culling nearly 800,000 birds, including vaccinated ducks; Germany leads wild bird cases at over 2,800 yearly, plus one H5N5 in Scotland. The UK confirms multiple December outbreaks in England, like large flocks in Lincolnshire and Norfolk per GOV.UK.

    Asia sees Japan with six broiler outbreaks since mid-October, totaling over 120,000 birds; South Korea at six laying hen events, including 130,000 birds; India with five Uttarakhand flocks over 21,000 birds; Iraq resuming after a gap. Africa rebounds: Nigeria with clustered backyard losses post-five-month silence, South Africa culling 150,000 on one farm plus 40 wild birds, per WOAH. The Americas log 508 bird outbreaks in nine countries via PAHO, with South America showing convergent routesavian from Argentina to Brazil and Uruguay, pinniped-adapted from Chile per phylogeographic analysis in PMC.

    Visualize trend lines: Europes poultry curve spikes upward, crossing 2023-2024 peaks; US dairy cattle infections plateau after clades B3.13 and D1.1 adaptations; global wild bird detections form a migratory wave from Asia-Europe to Americas since 2021 per Nature and ECDC. Comparative stats: H5N1 clade 2.3.4.4b infects over 200 mammal species worldwide; WHO notes 991 human cases since 2003 at 48% fatality, with Chinas four new pediatric H9N2 undisclosed until now.

    Cross-border patterns highlight wild bird migrations as primary vectors, impossible to fully control, enabling mammal jumps like dairy cows via open barns. South Americas dual phylogroups underscore this: wild bird-poultry from Andean Argentina, marine mammal strains dispersing inland with PB2 mutations Q591K and D701N.

    Containment mixed: UKs rapid culling and zoning succeeds locally; Frances vaccination falters in ducks. Failures include undetected reassortments, like Argentinas 2025 event acquiring LPAI segments.

    Emerging variants: H5N5 in US humans and Europe wild birds; mammal-adapted H5N1 persisting.

    Travel advisories: CDC urges avoiding sick birds, unpasteurized dairy; enhance biosecurity. No broad restrictions, but monitor WOAH updates.

    Thanks for tuning in. Come back next week for more. This has been a Quiet Please production. For me, check out Quiet Please Dot A I. Stay vigilant.

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    This content was created in partnership and with the help of Artificial Intelligence AI
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    4 分
  • H5N1 Avian Flu Spreads Globally: Urgent Updates on Outbreaks in Poultry, Wildlife, and Emerging Transmission Risks
    2025/12/12
    You’re listening to Avian Flu Watch: Global H5N1 Tracker.Today we’re taking a data-driven look at how highly pathogenic H5N1 avian influenza is moving across the globe, what the numbers show, and what they mean for travelers and public health.Let’s start with the global picture. The UN Food and Agriculture Organization reports that since October 2025, countries have officially notified more than 950 H5 avian influenza outbreaks in animals across 38 countries, confirming that H5N1 remains a truly global panzootic. The virus continues to circulate in wild birds on every major flyway and in commercial poultry on multiple continents.Regionally, Europe is in an active autumn–winter wave. The European Centre for Disease Prevention and Control notes new clusters in Germany, Czechia, Poland, and Spain, with many introductions traced either to long-range wild bird movements or to cross-border movements of poultry and contaminated equipment. In the United Kingdom, government surveillance lists 66 confirmed H5N1 outbreaks in the 2025–26 season so far, including 54 in England and multiple large commercial premises in Norfolk, Lincolnshire, and Cumbria under 3‑kilometer protection and 10‑kilometer surveillance zones.In North America, the US Centers for Disease Control and Prevention report that H5 bird flu is now entrenched in wild birds, poultry, and dairy cattle, with sporadic human infections but no sustained human-to-human transmission. Over the last month, summary data from the US Department of Agriculture compiled by CIDRAP show 38 newly infected flocks, including 24 commercial operations and 14 backyard flocks, affecting more than 4.4 million birds, with fresh turkey outbreaks in Minnesota alone involving over 100,000 birds.In South America, a recent open-access study in a medical journal describes how clade 2.3.4.4b H5N1 invaded the continent via Colombia, then spread through Peru and Chile into Argentina, Uruguay, and Brazil, even reaching Antarctic and sub‑Antarctic islands. Genetic analyses identify two main transmission routes into Uruguay: an avian route via Argentina and a pinniped, or seal, route via Chile, underlining how marine mammals have become an unexpected amplifier host.If we could visualize these data, you’d see a world map with bright hotspots over Western Europe, the US Midwest and South, and coastal South America. Trend lines for poultry outbreaks show seasonal peaks in the Northern Hemisphere each winter, but a rising multi-year baseline compared with pre‑2021 seasons. A bar chart of affected species now includes not just poultry and wild birds, but also dairy cattle and over a dozen wild mammal species.Cross-border transmission is driven primarily by three mechanisms. First, long-distance migratory birds, linking Arctic breeding grounds with wintering areas in Europe, Africa, and the Americas. Second, regional poultry trade and shared equipment, which European outbreak investigations repeatedly implicate. Third, spillover and spillback between birds, cattle, and mammals, documented in US dairy herds and South American marine mammals, which increases opportunities for viral adaptation.On containment, there are notable successes. Rapid culling, zoning, and movement controls in parts of the UK and the EU have shortened outbreak durations and prevented spread to neighboring farms. Some South American countries have quickly closed affected wildlife areas and enhanced genomic surveillance. Failures include delayed detection in dairy cattle in North America, patchy reporting in parts of Africa and Asia, and limited compensation schemes that discourage early reporting by smallholders.Emerging variants of concern include South American reassortants detected in Argentina that acquired several gene segments from local low-pathogenic viruses, and mammal-adapted strains with PB2 mutations linked to better replication in mammals. The World Health Organization has also highlighted a recent human H5 infection in the United States as another reminder of ongoing zoonotic risk, even though sustained human transmission has not been observed.For travelers, health agencies advise avoiding direct contact with birds, live bird markets, and farms in countries reporting active outbreaks; not touching sick or dead wild birds or mammals; and following any local restrictions on poultry farms or coastal wildlife areas. For those working with poultry, cattle, or wildlife, the key recommendations are strict biosecurity, personal protective equipment, and immediate reporting of unexplained animal illness.That’s it for this episode of Avian Flu Watch: Global H5N1 Tracker. Thanks for tuning in, and come back next week for more data-driven updates on evolving infectious disease threats. This has been a Quiet Please production. For more from me, check out QuietPlease.ai.For more http://www.quietplease.aiGet the best deals https://amzn.to/3ODvOtaThis content was created in partnership and with the help...
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    6 分
  • Global H5N1 Avian Flu Spreads Across Continents With Increasing Mammalian Transmission and Emerging Human Health Risks in 2025
    2025/12/10
    Avian Flu Watch: Global H5N1 Tracker

    This is Avian Flu Watch, your global H5N1 tracker. We’re monitoring the spread, the hotspots, and the evolving risk.

    Since early 2025, highly pathogenic H5N1 clade 2.3.4.4b has driven a sustained global epizootic. Wild birds remain the primary vector, with transmission now entrenched across North America, Europe, Africa, Asia, and South America. Antarctica reported its first H5N1 detection in late 2023, raising concerns about catastrophic breeding failures in immunologically naïve wildlife.

    In the Americas, the picture is complex. In 2025, nine countries reported 508 outbreaks in birds, with thousands of wild bird detections, especially in the United States and Canada. The virus has spread from North America into South America, primarily along migratory flyways. Phylogeographic studies show two main South American transmission routes: an avian-derived pathway originating in Argentina, and a pinniped-derived route from Chile, with Uruguay and Brazil acting as secondary sources. A notable 2025 reassortment event in Argentina, where H5N1 acquired four gene segments from a local low-pathogenic avian influenza virus, highlights the risk of new, potentially more transmissible variants emerging in the region.

    Europe continues to see widespread circulation. Hungary reported 10,000 crane deaths in a single event, underscoring the virus’s lethality in wild birds. Outbreaks persist in poultry and wild populations across multiple countries, with ongoing gene exchange between H5N1 and local flu strains.

    In Asia, the situation is mixed. China reported a human H5N1 case in early 2025 with co-infection of SARS-CoV-2, and genomic analysis shows complex reassortment between wild bird-origin H5 and bovine-origin H5N1 strains. In Southeast Asia, Cambodia has seen repeated human clusters, often linked to contact with sick poultry, with multiple fatalities in 2025. India also reported a fatal human H5N1 case this year.

    Between January and early September 2025, 19 human H5N1 infections were reported globally, including three deaths, in Bangladesh, Cambodia, China, and India. The World Health Organization reports that since 2003, 991 human H5N1 cases have been reported worldwide, with 476 deaths, a case fatality rate of about 48 percent.

    Containment has had both successes and failures. Rapid culling and movement restrictions in some European and Asian countries have limited spillover to humans. However, in parts of South America and Southeast Asia, limited genomic surveillance and delayed response have allowed the virus to establish in wild and domestic populations, creating persistent reservoirs.

    A major concern is the emergence of bovine-origin H5N1 in North America. These strains show evidence of transmission from infected cattle to poultry, cats, raccoons, and other mammals. Studies note that these viruses retain a long-stalk N1 neuraminidase, which improves mobility in mammalian respiratory mucus, and carry PB2 mutations that enhance replication in mammalian cells. Human infections among dairy workers, linked to raw milk and the production chain, point to novel zoonotic routes beyond traditional poultry contact.

    For travelers, the risk remains low but not zero. Avoid live bird markets, do not handle sick or dead birds, and avoid consuming raw milk or undercooked poultry in affected areas. Public health authorities emphasize that while efficient human-to-human transmission is not yet established, the ongoing spread in mammals and reassortment events demand heightened vigilance.

    Thank you for tuning in to Avian Flu Watch. Come back next week for more. This has been a Quiet Please production. For me, check out Quiet Please Dot A I.

    For more http://www.quietplease.ai

    Get the best deals https://amzn.to/3ODvOta

    This content was created in partnership and with the help of Artificial Intelligence AI
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    4 分