This episode offers a concise clinical review of Overactive Bladder (OAB) syndrome for practitioners. We cover the essential steps in diagnosis, from taking a focused history and ruling out red flags to the importance of urinalysis and post-void residual measurement.

The core of the discussion is the stepwise management framework:

• First-line: A review of foundational conservative therapies, including lifestyle advice and structured bladder training.
• Second-line: A comparison of pharmacotherapy options, focusing on the mechanisms and differing side-effect profiles of antimuscarinics versus the beta-3 agonist, mirabegron.
• Third-line: An overview of specialist treatments for refractory OAB, including intravesical botulinum toxin A and sacral neuromodulation.

Tune in for a practical update to guide your clinical management of OAB.

Keywords: Overactive Bladder (OAB) management; Urinary urgency diagnosis; Nocturia and frequency treatment; Antimuscarinics for OAB; Mirabegron Australia; Beta-3 agonists bladder; First-line OAB treatment; Bladder training and pelvic floor; Refractory OAB options; OAB in elderly patients; Australian General Practice guidelines; Urge incontinence vs OAB-wet; GP review of incontinence; Bladder diary use; Medical student urology.

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