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Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they speak with Dr. Christin Glorioso, an MIT-trained neuroscientist, physician, entrepreneur, and pioneer in the study of human brain aging. Dr. Glorioso is the co-founder and CEO of NeuroAge Therapeutics, where she combines neuroscience, genetics, biomarkers, and advanced technology to better understand how the brain ages and what we may be able to do about it.

For Dr. Glorioso, the science of longevity is also personal. After seeing Alzheimer's disease affect multiple generations of her family and learning about her own genetic risk, she became determined to better understand the aging process within the brain. That pursuit eventually led her to use herself as what she calls "guinea pig number one," tracking her own brain health while developing the comprehensive testing approach behind NeuroAge.

In this episode, Dr. Glorioso explores how changes in the brain can begin years before noticeable cognitive symptoms appear and why understanding those changes earlier could create new opportunities to protect long-term brain health. She discusses the importance of the hippocampus and memory, genetic risk factors such as APOE4, and how MRI imaging, blood biomarkers, cognitive testing, and other measurements can provide a more complete picture of how an individual's brain is aging.

The conversation also looks at what we can potentially do with that information. Dr. Glorioso discusses research surrounding exercise and hippocampal volume, along with the roles of nutrition, sleep, physical activity, social connection, and other lifestyle factors in supporting cognitive health.

Listeners will gain a deeper understanding of the emerging science of biological brain age, the difference between genetic risk and destiny, and how a more personalized and proactive approach may help us better understand and care for our brains throughout the aging process.

Find more of Dr. Christin Glorioso here:
https://drglorioso.substack.com/

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