Can you imagine falling for a girl so hard that through the years, with no hope of being reunited, that love remains as strong as ever?

At 40, Dr. Keegan Wade is the Chief of Trauma Surgery, a rising star at NYC General. She's immersed 24-7 in work that she once loved. No one waits for her at home and she has nothing to offer. Anxiety has her in a choke hold and she'd give anything to sleep more than two consecutive hours. At the urging of a friend, she takes a long overdue vacation, a cross country trip on a restored steam train, in hopes that time away from the pressures of her job will solve her problems.

At 39, Willow Lord is a recent college graduate, a social worker in desperate need of a job. Divorced nine years, she's lived in poverty, saving coins to buy cat food. Next month, the first payments on her student loans are due. She has no time for a vacation, but when her friend, a friend who won't take 'no' for an answer insists, she sends out resumes, and boards The Frisco Express—New York City to California.

As young teens, on a steam train, these two women fell in love. And on a steam train, twenty-six years later, they're given a second chance. But the years have taken them to drastically different places. Can they straddle their worlds and seize it?