『YARAL Pharma』のカバーアート

YARAL Pharma

YARAL Pharma

著者： yaralpharma
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 Welcome to Meet YARAL, a podcast designed to bridge the gap between pharmaceutical companies and the pharmacy profession through candid conversations with pharmacists, healthcare leaders, and YARAL’s executive team. Each episode highlights the vital role pharmacists play in patient care, unpacks challenges on the front lines, and explores how thoughtful collaboration can lead to better outcomes. Along the way, we share how YARAL’s “Doing Things Differently” approach is helping redefine relationships between industry and practice—from product innovation to patient impact. YARAL Pharma, launched in 2022, is the U.S. generics subsidiary of IBSA, a longstanding multinational pharmaceutical company headquartered in Lugano, Switzerland. The company is committed to delivering high-quality products across various therapeutic areas, ensuring continuity of supply, and providing affordable authorized and complex generic medicines. Subscribe to Meet YARAL and be part of the conversation that’s strengthening collaboration between pharmacy and the pharmaceutical industry.Copyright 2025 All rights reserved. 衛生・健康的な生活 身体的病い・疾患
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  • Hypothyroidism in Long-Term Care: The Pharmacist's Role | YARAL Pharma

    Hypothyroidism in Long-Term Care: The Pharmacist's Role | YARAL Pharma
    2025/10/09
    This podcast is sponsored by YARAL Pharma. In this episode, we are focusing on the management of hypothyroidism -- a treatable, but not curable condition – and will explore unique challenges for patients with hypothyroidism in long-term care – from tolerability and formulation considerations to consistent dosing and patient needs. Dr. Tamara Ruggles is not affiliated with YARAL Pharma. All views and opinions regarding hypothyroidism are solely her own and are not attributable to YARAL or the Pharmacy Podcast Network. IMPORTANT SAFETY INFORMATION for levothyroxine sodium capsules INDICATION AND USAGE Levothyroxine sodium capsules are L-thyroxine (T4) indicated for adults and pediatric patients 6 years and older with: Hypothyroidism - As replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidismPituitary Thyrotropin (Thyroid-Stimulating Hormone, TSH) Suppression - As an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well differentiated thyroid cancer Limitations of Use: Levothyroxine sodium capsules are not indicated for suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine-sufficient patients as there are no clinical benefits and overtreatment with Levothyroxine sodium capsules may induce hyperthyroidism.Levothyroxine sodium capsules are not indicated for treatment of transient hypothyroidism during the recovery phase of subacute thyroiditis WARNING: NOT FOR THE TREATMENT OF OBESITY OR FOR WEIGHT LOSS Thyroid hormones, including levothyroxine sodium capsules, either alone or with other therapeutic agents, should not be used for the treatment of obesity or for weight loss. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects. Contraindications Uncorrected adrenal insufficiency Warnings and Precautions Cardiac adverse reactions in the elderly and in patients with underlying cardiovascular disease: Initiate Levothyroxine sodium capsules at less than the full replacement dose because of the increased risk of cardiac adverse reactions, including atrial fibrillation Myxedema coma: Do not use oral thyroid hormone drug products to treat myxedema comaAcute adrenal crisis in patients with concomitant adrenal insufficiency: Treat with replacement glucocorticoids prior to initiation of levothyroxine sodium capsules treatmentPrevention of hyperthyroidism or incomplete treatment of hypothyroidism: Proper dose titration and careful monitoring is critical to prevent the persistence of hypothyroidism or the development of hyperthyroidismWorsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. Carefully monitor glycemic control after starting, changing, or discontinuing thyroid hormone therapyDecreased bone mineral density associated with thyroid hormone over-replacement: Over-replacement can increase bone reabsorption and decrease bone mineral density. Give the lowest effective dose Adverse Reactions Common adverse reactions with levothyroxine therapy are primarily those of hyperthyroidism due to therapeutic overdosage. They include the following: General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweatingCentral Nervous System: headache, hyperactivity, nervousness, anxiety, irritability, emotional ability, insomniaMusculoskeletal: tremors, muscle weaknessCardiovascular: palpitations, tachycardia, arrythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrestRespiratory: dyspneaGastrointestinal (GI): diarrhea, vomiting, abdominal cramps, elevations in liver function testsDermatologic: hair loss, flushingEndocrine: decreased bone mineral densityReproductive: menstrual irregularities, impaired fertility Adverse Reactions in Children Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in children receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in children with resultant compromised adult height. Seizures have been reported rarely with the institution of levothyroxine therapy. Hypersensitivity Reactions Hypersensitivity reactions to inactive ingredients (in this product or other levothyroxine products) have occurred in patients treated with thyroid hormone products. These include urticaria, pruritis, skin rash, flushing, angioedema, various GI symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness and wheezing. Hypersensitivity to levothyroxine itself is not known to occur. Drug Interactions: Many ...
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    48 分
  • Targeted Acute Pain Relief: The Role of Topical NSAID Patches in Sports Medicine | Yaral Pharma

    Targeted Acute Pain Relief: The Role of Topical NSAID Patches in Sports Medicine | Yaral Pharma
    2025/07/30

    In this episode, YARAL Pharma CEO, Stephen Beckman joins clinical sports pharmacist Jessica Beal, PharmD. to discuss an important topic for athletes and active individuals – the role topical NSAID patches can play in acute pain management.

    Listeners can visit www.YARALPharma.com to learn more about the company and its products or connect on LinkedIn.

    Diclofenac Epolamine Topical System 1.3%

    Diclofenac Epolamine Topical System 1.3% is a nonsteroidal anti-inflammatory drug (NSAID) used for treating acute pain from minor strains, sprains, and bruises in adults and children aged 6 and older.

    Serious side effects may include increased risk of cardiovascular and gastrointestinal (GI) events. NSAIDs can raise the risk of heart attack, stroke, gastrointestinal bleeding, ulceration, and perforation of the stomach and intestines, which can be fatal. The risk for serious cardiovascular events may occur early in treatment and may increase with duration of use. Elderly patients and those with a history of peptic ulcer disease or GI bleeding are at higher risk for serious GI events.

    Do not use in patients who are allergic to diclofenac or any of its ingredients, or have a history of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. Do not use in the setting of coronary artery bypass graft surgery. Avoid use on broken skin. Discontinue immediately if signs of hypersensitivity occur.

     

    Patients should be informed about the warning signs and symptoms of liver problems. Discontinue use if abnormal liver tests persist or worsen or if signs of liver disease develop. Avoid using Diclofenac Epolamine Topical System 1.3% in patients with severe heart failure unless the benefits are expected to outweigh the risks.

    The most common side effects include itching, nausea, and headache. Patients should stop use and consult their doctor at the first sign of skin rash or other signs of sensitivity.

    Patients should ask their doctor if Diclofenac Epolamine Topical System 1.3% is right for them. For more information and Full Prescribing Information including Boxed Warning and Important Safety Information, visit www.yaralpharma.com

    Dr. Beal is not affiliated with YARAL Pharma. All views and opinions regarding pain management are solely her own and are not attributable to YARAL or the Pharmacy Podcast Network.

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    37 分
  • Advantages of Levothyroxine Capsule Over Tablet | YARAL Pharma

    Advantages of Levothyroxine Capsule Over Tablet | YARAL Pharma
    2025/01/16
    Every year, millions of patients rely on Levothyroxine to manage their hypothyroidism, but it's important to note that not all Levothyroxine medications are the same. In today’s episode of the Pharmacy Podcast Network, we’ll explore the management of hypothyroidism and discuss how alternative dosage forms might be the solution for patients who struggle with traditional tablet formulations. When it comes to the management of hypothyroidism, not all levothyroxine medications are created equal.
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    39 分
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