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A vibrant young Hispano woman, Shonnie Medina, inherits a breast-cancer mutation known as BRCA1.185delAG. It is a genetic variant characteristic of Jews. The Medinas knew they were descended from Native Americans and Spanish Catholics, but they did not know that they had Jewish ancestry as well. The mutation most likely sprang from Sephardic Jews hounded by the Spanish Inquisition. The discovery of the gene leads to a fascinating investigation of cultural history and modern genetics by Dr. Harry Ostrer and other experts on the DNA of Jewish populations.

In Strange Bedfellows, David P. Barash and Judith Eve Lipton look at how biology actually promotes monogamy in some species and how these lessons apply to human beings. An accessible work of science that is relevant to our intimate daily life, Strange Bedfellows will reassure some people, surprise others, and engage everyone.

While we joke that men are from Mars and women are from Venus, our gender differences can't compare to those of other animals. For instance: the male garden spider spontaneously dies after mating with a female more than fifty times his size. Female cichlids must guard their eggs and larvae--even from the hungry appetites of their own partners. And male blanket octopuses employ a copulatory arm longer than their own bodies to mate with females that outweigh them by four orders of magnitude. Why do these gender gulfs exist?

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?

Delve deeper into the scientific terms and theories at the core of the Peabody-winning, cult favorite show. With exclusive insights from the show's cocreator, Graeme Manson, and science consultant Cosima Herter, The Science of Orphan Black takes you behind the closed doors of the Dyad Institute and inside Neolution.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.

La specie umana, unica tra le specie viventi, è in grado di ricostruire la propria storia biologica. Da un lato tutti gli uomini appartengono a una sola specie, dall'altro non esistono due uomini uguali sulla terra, tanto è grande la variabilità genetica tra individuo e individuo. Unica tra le specie è anche la nostra complessa storia culturale e tra le due evoluzioni, biologica e culturale, esistono convergenze ma anche divergenze.

I nostri geni non sono scolpiti nella pietra e i nostri fattori ereditari non sono un' "impronta digitale" fissa e immodificabile. Un essere umano infatti è molto più della somma dei suoi geni. Tutto quello che mangiamo, facciamo e sentiamo, tutto ciò che ci accade può influire sull'attività del DNA, a prescindere dalla configurazione genetica con la quale nasciamo. L'epigenetica, cioè la branca della genetica che si occupa di indagare le variazioni dell'espressione del nostro DNA, ci porta infatti una buona notizia: tali variazioni sono reversibili.