検索キーワード： 歴史・解説

Com a precisão de um biólogo, a visão de um historiador e a paixão de um biógrafo, o oncologista Siddhartha Mukherjee traça uma biografia detalhada do câncer, do primeiro registro às mais avançadas pesquisas, últimas descobertas e expectativas para o futuro, abrindo caminho para a desmitificação dessa doença tão temida.

Seamus O'Mahony writes about the illusion of progress, the notion that more and more diseases can be "conquered" ad infinitum. He punctures the idiocy of consumerism, the idea that healthcare can be endlessly adapted to the wishes of individuals. He excoriates the claims of Big Science, the spending of vast sums on research follies like the Human Genome Project. And he highlights one of the most dangerous errors of industrialized medicine: an over-reliance on metrics, and a neglect of things that can't easily be measured, like compassion.

The Fourth History of Man continues with virus infections where The Third History of Man left off: hashing out those specks of genetic schmutz, covering the R-naught of those naughty infectious scoundrels. Some big hitters will be considered, from polio and the famous celebrities that had it, through 50 shades of hepatitis, rabies and the hair of the dog, and the monkey business of HIV and AIDS. Leaving viruses, we’ll delve into a study of parasites, including the parasite of all parasites, Sigourney Weaver’s alien.

In the last half of the twentieth century, Don Thomas discovered a cure for every marrow-based disease—like leukemia, lymphoma, and sickle-cell anemia—forever changing treatment for some of the deadliest illnesses. His feats were extraordinary, earning him a Nobel Prize, and the cascade of treatments he inspired have reshaped and will continue to reshape the practice of clinical medicine. Yet no one has ever written Thomas’s courageous story.Dr. Frederick R. Appelbaum, a member of Thomas’s research team, does so for the first time.

No Centro Hospitalar Psiquiátrico de Barbacena, conhecido apenas por Colônia, ocorreu uma das maiores barbáries da história do Brasil. O centro recebia diariamente, além de pacientes com diagnóstico de doença mental, homossexuais, prostitutas, epiléticos, mães solteiras, meninas problemáticas, mulheres engravidadas pelos patrões, moças que haviam perdido a virgindade antes do casamento, mendigos, alcoólatras, melancólicos, tímidos e todo tipo de gente considerada fora dos padrões sociais.

Quando Jennifer Doudna ainda cursava a sexta série, encontrou em sua cama um exemplar de A dupla hélice, de James Watson, deixado por seu pai. Avançando pelas páginas, Doudna ficou fascinada com os bastidores da competição científica pela descoberta dos tijolinhos que constroem a vida. Motivada pela paixão de entender o funcionamento da natureza e por transformar descobertas em invenções práticas, Doudna ajudaria a realizar aquilo que o próprio James Watson, um dos descobridores da estrutura do DNA, classificara como o próximo avanço científico mais importante da biologia.

Em 1918, um novo vírus de influenza, até então restrito às aves, passou a se manifestar também em humanos. Um ano mais tarde, o saldo era de pelo menos 100 mil mortos daquela que ficaria conhecida na história como gripe espanhola, marcando o primeiro grande embate entre a ciência e uma pandemia. Em apenas dois anos o vírus matou mais pessoas do que a Aids em todo o mundo ao longo dos 24 anos desde a sua descoberta, e mais pessoas em um ano do que a peste negra ao longo de um século.

Plagues, pandemics, and infectious diseases have shaped the history of the Jewish people. Of course, there were the ten biblical plagues that famously smote the Egyptians—from the rain of frogs to the deaths of the firstborn—but that is just the start of the story. In The Eleventh Plague, Brown investigates the relation between Judaism and infectious diseases throughout the ages, from premodern and early-modern plagues, to rabbinic responses to smallpox and cholera, and to the curious practice of "Black Weddings" in which two orphans are married in a cemetery.

If you want to make a living by transitioning into the medical writing field as a freelancer or by working a job, then this book is for you. It doesn’t matter if you have previous experience working in the medical field or not, as this field has a vast array of opportunities.

Auf der ganzen Welt lernen Ärzte und Ärztinnen von echten Krankheiten und Patienten. Sie lernen, wie sich Symptome äußern und wie man sie lindern oder sogar heilen kann. Manche dieser Fälle und Menschen sind so besonders, dass sie in die Geschichte eingehen. Im zweiten Band Rätselhafte Fälle der Medizingeschichte lädt Autor und Arzt Roy Benaroch wieder ein, mit ihm zusammen auf Spurensuche zu gehen. Anhand historischer Quellen zeichnet er das Leben bekannter historischer Persönlichkeiten nach und fahndet nach Hinweisen zu ihren Krankheiten und Symptomen.

In Germany on Christmas Day 1956 a baby girl was born without ears. She was the first victim of the notorious thalidomide epidemic. There would be over 10,000 more across 46 countries. For years the world believed the United States had avoided the catastrophe. After Frances Kelsey at the FDA became suspicious of the dangers of thalidomide in 1960, she led a successful fight to block its commercial approval. But now, having probed government and corporate archives and interviewed hundreds of key players, Jennifer Vanderbes reveals a darker truth that lay buried for decades.

Doctors at War tells the stories of physicians in France working to impede the German war effort and undermine French collaborators during the Occupation from 1940 to 1945. Determined to defeat the Third Reich's incursion, one group of prominent Paris doctors founded a medical network to treat injured Resistance fighters who they then secretly transported to Allied countries to avoid forced labor in Germany. Doctors at War stands as a dramatic, character-driven account of physicians' courage and resilience in the face of evil.

In 1959, a Cincinnati pharmaceutical firm, the William S. Merrell Company, quietly began distributing samples of an exciting new wonder drug already popular around the world. Touted as a sedative without risks, thalidomide was handed out freely, under the guise of clinical trials, by doctors who believed approval by the Food and Drug Administration was imminent. But in 1960, when the application for thalidomide landed on the desk of FDA medical reviewer Frances Kelsey, she quickly grew suspicious.

Notre rapport à la santé a changé. Les traitements se sont diversifiés. Face à un problème de mal-être ou de santé, nous ne savons pas toujours vers qui nous tourner ou qui consulter. Se donner toutes les chances, c'est découvrir les bienfaits des médecines conventionnelles et complémentaires, mais aussi mesurer à quel point notre propre rôle est essentiel. Natacha Calestrémé donne la parole à des médecins et des chercheurs reconnus pour leur expertise scientifique et leur connaissance des pratiques thérapeutiques, et ouvre de nouveaux horizons pour nous aider à aller mieux.

Beginning with the origins of the concept of mania—and the term maniac—in ancient Greek and Roman civilizations, renowned psychiatrist David Healy examines how concepts of mental afflictions evolved as scientific breakthroughs established connections between brain function and mental illness. Healy recounts the changing definitions of mania through the centuries, explores the effects of new terminology and growing public awareness of the disease on culture and society, and examines the rise of psychotropic treatments and pharmacological marketing over the past four decades.

Human history hinges on the battle to confront our most dangerous enemies—the half-dozen diseases responsible for killing almost all of mankind. The story of our medical triumphs reveals an inspiring tapestry of human achievement, but the journey was far from smooth. It is a tale replete with dramatic episodes as spellbinding as any blockbuster Hollywood movie. In The Masters of Medicine, Dr. Andrew Lam, an award-winning author and retinal surgeon, distills the long arc of medical progress down to the crucial moments that were responsible for the world's greatest medical miracles.

Medical science has made brilliant discoveries over the last century but as any cancer patient can attest, it has yet to conquer, or even fully comprehend, pain. Beginning with his own battle against severe migraines, and citing numerous case studies of his patients, in Why We Hurt Dr. Frank Vertosick explains how pain evolved, and by highlighting the critical functions it serves, he helps us to understand its value.

After the unprecedented events of the COVID-19 pandemic, it may be hard to imagine a time not so long ago when deadly diseases were a routine part of life. It is harder still to fathom that the best medical thinking at that time blamed these diseases on noxious miasmas, bodily humors, and divine dyspepsia. This all began to change on a day in April 1676, when a little-known Dutch merchant described bacteria for the first time. Ending Epidemics explains how we came to understand and prevent many of our worst infectious diseases—and double average life expectancy.

Videnskaben har altid eksperimenteret på mennesker, og resultaterne har haft stor betydning for meget af det, vi i dag ved om menneskekroppen og sindet. De fleste steder i verden er der strenge etiske regler for, hvordan videnskabelige forsøg bliver udført. Men sådan har det ikke altid været. I serien EKSPERIMENTER MED MENNESKER dykker vi ned i nogle af historiens mest grusomme menneskeforsøg. Forsøgene revolutionerede videnskaben, men havde frygtelige konsekvenser for de involverede.

JAK UPÓR I TROCHĘ SZCZĘŚCIA ZMIENIŁY ŚWIAT Czy wiesz, że: miniaturowy odłamek plastiku w oku pilota RAF-u sprawił, że dziś używamy tego materiału do produkcji sztucznych soczewek; tytanowa komora, która za nic nie dawała usunąć się z kości królika, doprowadziła do powstania implantów dentystycznych; viagrę zawdzięczamy grupie chemików pracujących nad nowym lekiem mającym przynieść ulgę cierpiącym z powodu dusznicy bolesnej; pięć wyjątkowo ciepłych tygodni 1928 roku pomogło Alexandrowi Flemingowi w odkryciu penicyliny.