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The search for hope is most urgent at the patient's bedside. The Anatomy of Hope takes us there, bringing us into the lives of people at pivotal moments when they reach for and find hope - or when it eludes their grasp. Through these intimate portraits, we learn how to distinguish true hope from false, why some people feel they are undeserving of it, and whether we should ever abandon our search.

Weaving together family history, genetic discovery, and scenes from her life, Ami McKay tells the compelling, true-science story of her own family's unsettling legacy of hereditary cancer while exploring the challenges that come from carrying the mutation that not only killed many people you loved, but might also kill you.

Karen M. Masterson, a journalist turned malaria researcher, uncovers the complete story behind this dark tale of science, medicine and war. Illuminating, riveting and surprising, The Malaria Project captures the ethical perils of seeking treatments for disease while ignoring the human condition.

From the author of the number-one New York Times best seller On Tyranny comes an impassioned condemnation of America's pandemic response and an urgent call to rethink health and freedom.

The COVID-19 pandemic is the most significant health emergency of our time. Writing from Italy in lockdown, physicist and novelist Paolo Giordano explains how disease spreads in our interconnected world.

A puzzling series of dental explosions beginning in the 19th century is just one of many strange tales that have long lain undiscovered in the pages of old medical journals. Award-winning medical historian Thomas Morris delivers one of the most remarkable, cringe-inducing collections of stories ever assembled.

Interweaving history, original reportage, and personal narrative, Pandemic explores the origin of epidemics, drawing parallels between the story of cholera - one of history's most disruptive and deadly pathogens - and the new pathogens that stalk humankind today, from Ebola and avian influenza to drug-resistant superbugs.

In 1918, the world faced the deadliest pandemic in human history. What can the story of the so-called Spanish Flu teach us about the fight against present day crises and how to prepare for future outbreaks? At the height of WWI, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 months than AIDS killed in 24 years, more in a year than the Black Death killed in a century.

Witness early, bloody, anaesthetic-free operations and first crude surgical instruments, trace the mapping of the circulatory system, follow the painstaking detective work that led to the decoding of the human genome and understand the role that potions, cures, therapies, herbal medicines and drugs have played in the human quest to tame and conquer disease, injury and death. An engrossing history and tale of drama and discovery that celebrates the milestones of medical history across generations and cultures.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

In the late 1990s, a young physician in Albuquerque, New Mexico, published a stunning memoir of his experiences in the highly charged world of the ER. Presented in a series of powerful, poetic vignettes, The Blood of Strangers became an instant classic. Now, over two decades later, Dr. Frank Huyler delivers another dispatch from the trenches—this time from the perspective of middle age. In portraits visceral, haunting, sometimes surreal, Huyler reveals the gritty reality of medicine practiced on the razor’s edge between life and death.

The heart of many hospitals is the Neonatal Intensive Care Unit (NICU). It is a place where humanity, ethics, and science collide in dramatic and deeply personal ways as parents, doctors, and nurses grapple with sometimes unanswerable questions: When does life begin? When and how should life end? And what does it mean to be human? Nearly 20 years ago, Dr. John D. Lantos wrote The Lazarus Case, a seminal work on ethical dilemmas in neonatology. He described the NICU as “a strong, strange, powerful place”. The

An acclaimed medical expert and patient advocate offers an eye-opening look at many common and widely used medical interventions that have been shown to be far more harmful than helpful. Yet, surprisingly, despite clear evidence to the contrary, most doctors continue to recommend them.

At the University of Wisconsin, Dr. Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.

No Centro Hospitalar Psiquiátrico de Barbacena, conhecido apenas por Colônia, ocorreu uma das maiores barbáries da história do Brasil. O centro recebia diariamente, além de pacientes com diagnóstico de doença mental, homossexuais, prostitutas, epiléticos, mães solteiras, meninas problemáticas, mulheres engravidadas pelos patrões, moças que haviam perdido a virgindade antes do casamento, mendigos, alcoólatras, melancólicos, tímidos e todo tipo de gente considerada fora dos padrões sociais.

The Fourth History of Man continues with virus infections where The Third History of Man left off: hashing out those specks of genetic schmutz, covering the R-naught of those naughty infectious scoundrels. Some big hitters will be considered, from polio and the famous celebrities that had it, through 50 shades of hepatitis, rabies and the hair of the dog, and the monkey business of HIV and AIDS. Leaving viruses, we’ll delve into a study of parasites, including the parasite of all parasites, Sigourney Weaver’s alien.

Quando Jennifer Doudna ainda cursava a sexta série, encontrou em sua cama um exemplar de A dupla hélice, de James Watson, deixado por seu pai. Avançando pelas páginas, Doudna ficou fascinada com os bastidores da competição científica pela descoberta dos tijolinhos que constroem a vida. Motivada pela paixão de entender o funcionamento da natureza e por transformar descobertas em invenções práticas, Doudna ajudaria a realizar aquilo que o próprio James Watson, um dos descobridores da estrutura do DNA, classificara como o próximo avanço científico mais importante da biologia.

Em 1918, um novo vírus de influenza, até então restrito às aves, passou a se manifestar também em humanos. Um ano mais tarde, o saldo era de pelo menos 100 mil mortos daquela que ficaria conhecida na história como gripe espanhola, marcando o primeiro grande embate entre a ciência e uma pandemia. Em apenas dois anos o vírus matou mais pessoas do que a Aids em todo o mundo ao longo dos 24 anos desde a sua descoberta, e mais pessoas em um ano do que a peste negra ao longo de um século.

In the last half of the twentieth century, Don Thomas discovered a cure for every marrow-based disease—like leukemia, lymphoma, and sickle-cell anemia—forever changing treatment for some of the deadliest illnesses. His feats were extraordinary, earning him a Nobel Prize, and the cascade of treatments he inspired have reshaped and will continue to reshape the practice of clinical medicine. Yet no one has ever written Thomas’s courageous story.Dr. Frederick R. Appelbaum, a member of Thomas’s research team, does so for the first time.

O século XIX trouxe avanços tecnológicos e industriais em diversas áreas. Uma, porém, ficou para trás: a Medicina. Ao redor do planeta, a mortalidade infantil alcançava taxas altíssimas e a expectativa de vida era baixa. Doenças diversas castigavam a população. Mas o cenário mudou ao longo do século XX. Este audiolivro narra, de forma deliciosa, como médicos e cientistas lançavam mão de criatividade, coragem e raciocínio lógico para tornar os progressos possíveis.