検索キーワード： 歴史・解説

John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the 20th century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today.

Picking up where Berton Roueche's The Medical Detectives left off, The Deadly Dinner Party presents 15 edge-of-your-seat, real-life medical detective stories written by a practicing physician. Award-winning author Jonathan Edlow, MD, shows the doctor as detective and the epidemiologist as elite sleuth in stories that are as gripping as the best thrillers.

In World War II, 59,000 women voluntarily risked their lives for their country as US Army nurses. For more than half a century these women's experiences remained untold, almost without reference in books, historical societies, or military archives. After years of research and hundreds of hours of interviews, Evelyn M. Monahan and Rosemary Neidel-Greenlee have created a dramatic narrative that at last brings to light the critical role that women played throughout the war.

The gripping story of a chemical weapons catastrophe, the cover-up, and how one American Army doctor’s discovery led to the development of the first drug to combat cancer, known today as chemotherapy.

The Cancer Problem offers the first medical, cultural, and social history of cancer in 19th-century Britain. It argues that it was in the 19th century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present.

Elizabeth Blackwell believed from an early age that she was destined for a mission beyond the scope of "ordinary" womanhood. Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an MD. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.

Against a global backdrop of wartime suffering and postwar hope, Borrowing Life gathers the personal histories of the men and women behind the team that enabled and performed the modern medical miracle of the world's first successful organ transplant.

In this extended lyric essay, a poet mines her lifelong experience with migraines to deliver a marvelously idiosyncratic cultural history of pain - how we experience, treat, and mistreat it. Her sources range from the trial of Joan of Arc to the essays of Virginia Woolf and Elaine Scarry to Hugh Laurie’s portrayal of Gregory House on House M.D. As she engages with science, philosophy, visual art, rock lyrics, and field notes from her own medical adventures (both mainstream and alternative), she finds a way to express the often-indescribable experience of living with pain.

Today, 90 percent of psychiatric beds are located in jails and prisons across the United States, institutions that confine disproportionate numbers of African Americans. After more than a decade of research, the celebrated scholar and activist Mab Segrest locates the deep historical roots of this startling fact, turning her sights on a long-forgotten cauldron of racial ideology: the state mental asylum system in which psychiatry was born and whose influences extend into our troubled present.

Following the trail of an unexpected family connection, acclaimed journalist Pam Fessler has unearthed the lost world of the patients, nurses, doctors, and researchers at Carville who struggled for over a century to eradicate Hansen's disease, the modern name for leprosy. Amid widespread public anxiety about foreign contamination and contagion, patients were deprived of basic rights - denied the right to vote, restricted from leaving Carville, and often forbidden from contact with their own parents or children.

Just like us, medieval men and women worried about growing old, got blisters and indigestion, fell in love, and had children. And yet their lives were full of miraculous and richly metaphorical experiences radically different from our own, unfolding in a world where deadly wounds might be healed overnight by divine intervention, or where the heart of a king, plucked from his corpse, could be held aloft as a powerful symbol of political rule.

Dr. Lange graduated from medical school in 1981, right as a new plague swept across the globe. His story became intertwined with the story of HIV. At once a physician, scientist, AIDS activist, and medical diplomat, Lange studied ways to battle HIV and prevent its spread from mother to child. Fighting the injustices of poverty, Lange advocated for better access to health care for the poor and the vulnerable. The Impatient Dr. Lange is the story of one man's struggle against a global pandemic - and the tragic attack that may have slowed down the search for a cure.

For Chinese immigrant Wong Chut King, surviving in San Francisco meant a life in the shadows. His passing on March 6, 1900, would have been unremarkable if a city health officer hadn't noticed a swollen black lymph node on his groin - a sign of bubonic plague. Empowered by racist pseudoscience, officials rushed to quarantine Chinatown while doctors examined Wong's tissue for telltale bacteria. If the devastating disease was not contained, San Francisco would become the American epicenter of an outbreak that had already claimed 10 million lives worldwide.

Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 "parrot fever" pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.

This book covers the history of 12 important diseases and addresses public health responses and societal upheavals.

The Tudor dynasty died out because there was no heir of Elizabeth I's body to succeed her. Henry VIII, despite his six marriages, had produced no legitimate son who would live into old age. Three of the reigning Tudors (Edward VI, Mary I, and Elizabeth I) died without heirs apparent, the most tragic case being that of Mary Tudor, who went through two recorded cases of phantom pregnancy. If it were not for physical frailty and the lack of reproductive health among the Tudors, the course of history might have been different.

Decades of data cannot be ignored: African-American adults are far more likely to develop Type 2 diabetes than white adults. In a rousing indictment of the idea that notions of biological race should drive scientific inquiry, Sweetness in the Blood provides an ethnographic picture of biotechnology's framings of Type 2 diabetes risk and race and, importantly, offers a critical examination of the assumptions behind the recruitment of African American and African-descent populations for Type 2 diabetes research.

From yellow fever to smallpox to polio to AIDS to COVID-19, epidemics have prompted Americans to make choices and answer questions about their basic values and their laws. In five concise chapters, historian John Fabian Witt traces the legal history of epidemics, showing how infectious disease has both shaped, and been shaped by, the law.

The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the 20th century. Into this crisis stepped Walter Freeman, MD, who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman's documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.

Hippocrates revolutionized the study of medicine in Ancient Greece, but some of his ideas still influence the medical field today. In his book On Ulcers, Hippocrates details the recommended treatment for this ailment. While modern medicine has moved beyond using honey, boiled leaves, and white wine to treat ulcers, Hippocrates’ advice on diet and rest hold true. This text is fascinating for anyone interested in the historical development of medical practices.