検索キーワード： 歴史・解説

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

The End of the Beginning is a remarkable history of cancer treatment and the evolution of our understanding of its dynamic interplay with the immune system. Through Michael Kinch’s personal experience as a cancer researcher at Washington University and the head of the oncology program at a leading biotechnology company, we witness the incredible accumulation of breakthrough science and its rapid translation into life-saving technologies that have begun to dramatically increase the quality and quantity of life for cancer patients.

In the 16th century, when explorers travelled deep into the jungles of South America in search of gold and spices, they brought back many colourful tales of their adventures. None of these tales was more astonishing, or caused more concern, than that of the mystical properties of the substance with which the natives anointed their darts and arrows.

In 1968, Bruce Tucker, a Black man, went into Virginia’s top research hospital with a head injury, only to have his heart taken out of his body and put into the chest of a White businessman. Now, in The Organ Thieves, Pulitzer Prize-nominated journalist Chip Jones exposes the horrifying inequality surrounding Tucker’s death and how he was used as a human guinea pig without his family’s permission or knowledge.

Psychedelic drugs are making a comeback. In the mid-20th century, scientists actively studied the potential of drugs like LSD and psilocybin for treating mental health problems. After a decades-long hiatus, researchers are once again testing how effective these drugs are in relieving symptoms for a wide variety of psychiatric conditions, from depression and obsessive-compulsive disorder to posttraumatic stress disorder and substance addiction.

After his father died, James L. Nolan, Jr., took possession of a box of private family materials. To his surprise, the small secret archive contained a treasure trove of information about his grandfather's role as a doctor in the Manhattan Project. Dr. Nolan, it turned out, had been a significant figure.

Nearly two decades after it closed, the South Carolina State Hospital continues to hold a palpable mystique in Columbia and throughout the state. Founded in 1821 as the South Carolina Lunatic Asylum, it housed, fed, and treated thousands of patients incapable of surviving on their own. The patient population in 1961 eclipsed 6,600, well above its listed capacity of 4,823. By the mid-1990s, the patient population had fallen under 700, and the hospital had become a symbol of captivity, horror, and chaos.

Ignác Semmelweis is remembered for the now-commonplace notion that doctors must wash their hands before examining patients. In mid-19th century Vienna, however, this was a subversive idea. With deaths from childbed fever exploding, Semmelweis discovered that doctors themselves were spreading the disease. While his simple reforms worked immediately - childbed fever in Vienna all but disappeared - they brought down upon Semmelweis the wrath of the establishment, and led to his tragic end.

Between the years 1918 and 1920, influenza raged around the globe in the worst pandemic in recorded history, killing at least 50 million people, more than half a million of them Americans. Yet despite the devastation, this catastrophic event seems but a forgotten moment in our nation's past. American Pandemic offers a much-needed corrective to the silence surrounding the influenza outbreak.

Still Not Safe is the story of the rise of the patient - safety movement - and how an "epidemic" of medical errors was derived from a reality that didn't support such a characterization. Physician Robert Wears and organizational theorist Kathleen Sutcliffe trace the origins of patient safety to the emergence of market trends that challenged the place of doctors in the larger medical ecosystem.

He has been called the greatest surgeon of the 20th century. The son of Lebanese immigrants, Michael DeBakey rose from humble beginnings in a backwater Louisiana town to dominate the landscape of modern medicine. His contributions to our understanding and treatment of cardiovascular disease, in particular, were innumerable and epoch-making. DeBakey led a life of high drama, from the streets of Jazz Age New Orleans and the operating theaters of pre-war Europe, to the battlefields of World War II and the floodwaters of Hurricane Katrina.

John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the 20th century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today.

In World War II, 59,000 women voluntarily risked their lives for their country as US Army nurses. For more than half a century these women's experiences remained untold, almost without reference in books, historical societies, or military archives. After years of research and hundreds of hours of interviews, Evelyn M. Monahan and Rosemary Neidel-Greenlee have created a dramatic narrative that at last brings to light the critical role that women played throughout the war.

The gripping story of a chemical weapons catastrophe, the cover-up, and how one American Army doctor’s discovery led to the development of the first drug to combat cancer, known today as chemotherapy.

Against a global backdrop of wartime suffering and postwar hope, Borrowing Life gathers the personal histories of the men and women behind the team that enabled and performed the modern medical miracle of the world's first successful organ transplant.

In this extended lyric essay, a poet mines her lifelong experience with migraines to deliver a marvelously idiosyncratic cultural history of pain - how we experience, treat, and mistreat it. Her sources range from the trial of Joan of Arc to the essays of Virginia Woolf and Elaine Scarry to Hugh Laurie’s portrayal of Gregory House on House M.D. As she engages with science, philosophy, visual art, rock lyrics, and field notes from her own medical adventures (both mainstream and alternative), she finds a way to express the often-indescribable experience of living with pain.

Today, 90 percent of psychiatric beds are located in jails and prisons across the United States, institutions that confine disproportionate numbers of African Americans. After more than a decade of research, the celebrated scholar and activist Mab Segrest locates the deep historical roots of this startling fact, turning her sights on a long-forgotten cauldron of racial ideology: the state mental asylum system in which psychiatry was born and whose influences extend into our troubled present.

Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Michael Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent - and could easily be undone. Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.

Following the trail of an unexpected family connection, acclaimed journalist Pam Fessler has unearthed the lost world of the patients, nurses, doctors, and researchers at Carville who struggled for over a century to eradicate Hansen's disease, the modern name for leprosy. Amid widespread public anxiety about foreign contamination and contagion, patients were deprived of basic rights - denied the right to vote, restricted from leaving Carville, and often forbidden from contact with their own parents or children.

Just like us, medieval men and women worried about growing old, got blisters and indigestion, fell in love, and had children. And yet their lives were full of miraculous and richly metaphorical experiences radically different from our own, unfolding in a world where deadly wounds might be healed overnight by divine intervention, or where the heart of a king, plucked from his corpse, could be held aloft as a powerful symbol of political rule.