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When Nell’s father makes a deathbed declaration that hints at a long-held secret, it reignites feelings of isolation that have plagued her for years. Her suspicions about the family’s past only deepen when her mother, Annie, who is losing her memories to dementia, starts making cryptic comments of her own. Thirty-five years earlier, Annie’s life was upended by a series of traumas - one shock after another that she buried deep in her heart. The decisions she made at the time were motivated by love, but she knew even then that nobody could ever understand what she did.

While at a casino to celebrate her birthday, Jess Clarke proposes a pact to her reserved sister, Liz, and their childhood friend Chloe: the three women will say yes to any adventure that comes their way. Jess is mourning her recent divorce, so the other two reluctantly agree. Twelve hours later, they awaken to the shocking consequences of their behavior.

Early into the tempestuous decade of her thirties, Rae Langdon struggles to work through a grief she never anticipated. With her father, Connor, she tends to their Ohio farm, a forty-acre spread that itself has enjoyed better days. As memories sweep through her, some too precious to bear, Rae gives shelter from a brutal winter to a teenager named Quinn Galecki.

Ever since her father died, Bernie’s life has been stagnant. When concerned friends and family suggest she join a hike through Alaska to gain new perspective, Bernie reluctantly agrees to go, even though she’s never been the adventurous type, unlike her namesake, Great-Aunt Bernice. Matthew is a struggling screenwriter who needs a week off the grid to gain some inspiration for a new project and to process the reappearance of his absent father. When the two meet at the trailhead, it’s annoyance at first sight.

Rainey’s grandmother makes a startling request: Take me home. To Ireland, the country she fled post-World War II. Though they’re inseparably close, Rainey knows few of her grandmother’s secrets. Until they arrive at Aisling—the majestic estate on the southern coast of Ireland where her grandmother was raised—and Rainey discovers a collection of seventy-year-old letters in a trunk.

Del Wensley, wife of the most celebrated preacher in Harlan County, tries to mind her place. Until her husband’s infidelity pushes an already strained marriage to a breaking point. Clinging to her last hope for self-respect, Del turns her back on the rigid life she’s known. A coal train is rolling through the valley. With her eyes wide open to the unfamiliar, and to the freedom she craves, Del takes to the rails.

It’s the hottest day of the 1976 heatwave and there’s not a breath of fresh air in the labour ward at Lincoln County Hospital. Michelle is having her fourth child, a girl, while beloved husband Dean is sipping a cold pint in the pub. Their little house is already bursting at the seams, but Michelle is sure they’ll find a way to stretch their budget and continue life as a blissfully chaotic happy family. They name their new baby Donna.

Lewis Madigan is young, gay, out of work, and getting antsy when he’s roped into providing end-of-life care for his insufferable homophobic neighbor, Chester Wheeler. Lewis doesn’t need the aggravation, just the money. The only requirements: run errands, be on call, and put up with a miserable old churl no one else in Buffalo can bear. After exchanging barbs, bickering, baiting, and pushing buttons, Chester hits Lewis with the big ask. Lewis can’t say no to a dying wish.

Wendy Moore hides her collection of pilfered bric-a-brac from everyone, including her husband. He thinks she licked her kleptomania in therapy more than a decade ago. Therapy did help, as did focusing her attention on motherhood. But now Wendy’s gardening and furniture-refinishing hobbies fill up only so much of the day, leaving the recent empty nester lonely and anxious—a combination likely to trigger her little problem. She needs a project, fast. Luckily, Harper Ross—a single, childless younger woman in desperate need of highlights—just moved in next door.

It’s been eight years since a tragic accident changed Mo Kaminski’s and Chloe Miller’s lives forever. Now in their midtwenties, they’re sharing an apartment in San Francisco and navigating the normal challenges of early adulthood. Along with their roommate, Hazel, they are making their marks on the world - Mo revolutionizing the news with her media start-up, Hazel using her big brain to anticipate the future, and Chloe rescuing abandoned strays in the city.

Nicole Palmieri is married to her job. As a user experience designer at Virtuality, an artificial intelligence company in Los Angeles, Nicole is at her desk from sunrise to sunset. She doesn’t have time for a social life (or a love life), but that’s perfectly fine with her. Until her best friend, Parisa Shahin, announces her engagement and asks Nicole to be her maid of honor. That’s when Nicole decides to meticulously schedule out the next six months of her life....

Caitlin Marshall's trying to go home to Minnesota for Christmas, but at the last minute she gives her airline ticket to a stranded soldier. So Cait spends the holidays with Joe Rockwell, who was a childhood friend - and is still a terrible tease, claiming that Cait's his wife. Oh, sure, they were "married" in a pretend ceremony when she was eight, but now Joe wants to make their "marriage" real!

When Charlotte and Philip meet, the pair form a deep and instant connection. Soon they’re settled in the Florida Keys with plans to marry. But just as they should be getting closer, Charlotte feels Philip slipping away. Second-guessing their love is something Charlotte never imagined, but with Philip’s excessive absences, she finds herself yearning for more. When she meets Ben, she ignores the pull, but the supportive single dad is there for her in ways she never knew she desired.

Peyton Prescott would give anything for the carefree life she knew before breast cancer changed everything. But instead of using her second chance to move forward, she’s stuck promoting the memoir her brother convinced her to write, thus reliving the very battle she wants to forget. If she hopes her European book tour will allow her to enjoy revisiting her favorite travel-writing destinations, she’s wrong: Her PR whiz is too consumed with his own goals to consider her needs.

Thirty-two-year-old Jess Abbot has lost everything: her job, her apartment, and - most heart-wrenching - her eight-year-old son, Chance, to a tragic accident. Haunted by memories and grief, Jess packs what’s left and heads for the small mountain town of Pine Lake, where she takes a position as caregiver to an eccentric old woman. A rumored clairvoyant, Lucy is strange but welcoming and immediately intuits Jess as a “loose end” in need of closure. But Jess isn’t the only guest in Lucy’s large Victorian home.

Dear friends and army wives Diana, Carmen, and Joanie have been through war, rumors of war, marital problems, motherhood, fears, joy, and heartache. But none of the women are prepared when their daughters decide to enlist in the army together. Facing an empty nest won’t be easy. Especially for Carmen. With emotions already high, she suffers an even greater blow: divorce papers. Diana understands the fury and tears. She’s been there.

After a year on the move, single mom Maggie Dalton has found a safe haven with her son in Maui. It’s the perfect spot to settle down now that her relentless stalker is finally behind bars. Maggie finds a new job and a new life thanks to some help from her best friend, Quinn, who urged her to come start over in paradise. But when signals suggest her stalker is back, Maggie realizes Maui might not be the safe oasis she thought. Quinn knows all about facing the past. Tenuously reunited with her biological family after thirty years, she’s still coming to terms with her childhood.

When an unexpected windfall brings together strangers Shauna and Frankie, one woman is popping champagne corks - but the other just wants to cry. For her part, Shauna is pouring celebratory drinks. Since her heart was broken and her dreams shattered, she’s been ready for a fresh start. Surely she deserves some good luck at last?

When Mackenzie, Sunna, and Maude move into a converted rental house, they are strangers with only one thing in common - important people in their lives have “ghosted” them. Mackenzie’s sister, Sunna’s best friend, and Maude’s fiancé - all gone with no explanation. So when a mangled, near-indecipherable letter arrives in their shared mailbox - hinting at long-awaited answers - each tenant assumes it’s for her.

At first glance Emma and Lucie seem very different, but they share an unspeakable vice. Beautiful, wealthy Emma appears to have it all with a loving husband and a seemingly successful life, but a restless craving has driven her to foolish actions. Meanwhile, young widow Lucie is struggling to make ends meet while coping with a troubled five-year-old.