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For personalized guidance and support with reversing & preventing Alzheimer's, you can reach out to Dr. Josh Helman directly. Visit his website at http://drjosh.com or contact his office at (407) 221-8841 to learn more about how he can help your journey to a healthier brain.

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Could our understanding of the brain’s immune system be completely rewritten? In this episode of Alzheimer's Breakthrough, host Dr. Josh Helman, MD speaks with Dr. Julia Belk, PhD from Stanford University about her ground-breaking research published in Nature.

Dr. Belk and her team discovered that in adult humans, microglia the resident immune cells responsible for maintaining brain health are not permanently isolated in the brain throughout life as previously believed. Instead, they are actively replaced by circulating immune cells originating from the blood and bone marrow. This paradigm-shifting discovery opens extraordinary new possibilities for treating Alzheimer’s disease, leveraging engineered cell therapies, and crossing the blood-brain barrier!

In this episode:

00:00 Introduction: Can Blood Help the Aging Brain?

03:00 What Are Microglia and Why Do They Matter?

07:00 The Surprising Link Between Blood Mutations and Alzheimer’s

12:00 How Blood Cells Replace the Brain’s Immune Cells

19:00 Why Human Brain Aging Differs from Animal Models

27:00 Can Microglia Lead to New Alzheimer’s Treatments?

36:00 Future Therapies, Gene Editing, and the Brain’s Immune System

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Connect with Dr. Julia Belk, PhD:

-X (Twitter)- https://x.com/juliabelk

-Email- jbelk@stanford.edu

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Connect with Dr. Josh Helman, MD:

- Substack - https://drjoshmd.substack.com/

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- Website - https://DrJosh.com

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Music promoted by https://www.chosic.com/free-music/all/

Creative Commons CC BY-SA 3.0

https://creativecommons.org/licenses/by-sa/3.0/

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Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

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