In this special video episode, Bernie and Anthony moderate a Common Sense Oncology discussion of key trials from ASH 2025! We are joined by special guest experts from across the globe to critically appraise the abstracts and discuss how they may or may not have changed clinical practice:

• Dr. Eddie Cliff (Australia) - Lymphoma
• Dr. Roberta Demichelis (Mexico) - Leukemia
• Dr. Manni Mohyuddin (USA) - Myeloma

Join the Common Sense Oncology movement here! https://commonsenseoncology.org/get-involved/

In this episode, Anthony and Bernie are joined by a panel of experts to discuss (and debate) everyone's favorite (or most feared) hematology topic - hemophagocytic lymphohistiocytosis (HLH)!

Joining us on this spicy episode are:

- Justin Kaner, MD

- Madeleine Ochs, PharmD, BCOP

- Catherine Johnson, PharmD, BCOP

How should we manage these patients? H-Scores or HLH2004 criteria? What is the role for ruxolitinib? Emapalumab? CXCL9 levels? Grab your favorite drink and have a listen!

Anthony and Bernie are joined by special guest Jonathan Gluck, award-winning journalist and author of "An Exercise in Uncertainty: A Memoir of Illness and Hope" for a powerful conversation about living through uncertainty.

Drawing on his decades-long journey with multiple myeloma, Jon reflects on the emotional, clinical, and existential uncertainties that shape living with cancer. The discussion moves beyond the patient experience to explore how uncertainty permeates everyday life, as well as oncology practice, including waiting for new therapies to become available, navigating logistical (and insurance) barriers, and interpreting evolving clinical trial data where the answers are not always clear.

Jon is graciously donating a portion of the proceeds of the book to multiple myeloma research, so everyone who picks up a copy is donating to a good cause!

https://www.penguinrandomhouse.com/books/760582/an-exercise-in-uncertainty-by-jonathan-gluck/