Yes, it's really called that, and yes, it comes from the same word you're thinking of. Spermidine is becoming bigger and bigger in the longevity world, and for good reason.

Today, Kyle's breaking down what spermidine actually is, why researchers are excited about its link to a cellular "clean-up" process called autophagy, whether it's connected to Japan's remarkably high number of centenarians, and which everyday foods (yes, including one very sticky Japanese staple) are the richest natural sources.

Plus: is the supplement version worth trying, or is food still your best bet?

In this episode:

• What spermidine is
• The autophagy connection: your body's cellular clean-up crew, and how spermidine may support it (without replacing fasting)
• Why natural spermidine levels decline with age, and what that might mean for healthy aging
• What the actual human research shows so far, including a small BDNF study and a larger observational trial, and where the evidence is still thin
• The best natural food sources of spermidine (natto, wheat germ, mushrooms, legumes, aged cheese), for people who will never touch a supplement
• Kyle's honest take on spermidine supplements, and why his current stance is "food first, supplement curious"
• Today's feelgood thing: the small, smug joy of being right

Studies mentioned:

• Nutraland rice germ extract pilot study coverage
• Longitudinal association of dietary spermidine with hepatic function indexes and cardiometabolic traits (European Journal of Nutrition)
• Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults (JAMA Network Open)

New here? feelgoodery is your weekly space for feeling good without pretending everything's fine - nutrition, mindset, and real strategies for showing up for yourself, hosted by Kyle Buchanan (Broadcaster, Speaker, Certified Nutritional Practitioner, Resident Wellness Contributor on Canada's The Morning Show & host of The Exhale on SiriusXM), and his live-studio dog Sam.

Disclaimer: This podcast is for informational purposes only and isn't a substitute for professional medical advice. Please always consult with your health care provider.

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