『University of California Audio Podcasts (Audio)』のカバーアート

University of California Audio Podcasts (Audio)

University of California Audio Podcasts (Audio)

著者： UCTV
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 UCTV delivers documentaries, faculty lectures, cutting-edge research symposiums and artistic performances from each of the ten UC campuses. Visit: uctv.tvCopyright 2024 Regents of the University of California
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  • The Hematopoietic Stem Cell Niche and Implications for Clinical Transplantation

    The Hematopoietic Stem Cell Niche and Implications for Clinical Transplantation
    2025/09/15
    Sean Morrison, Ph.D., from the Children’s Medical Center Research Institute at UT Southwestern, investigates how stem cells function, regenerate, and interact with their surrounding environment in the bone marrow. His research reveals how leptin receptor-positive cells—key components of the bone marrow niche—regulate hematopoietic stem cell maintenance and regeneration, influence platelet production, and respond to physiological stress like pregnancy. Morrison uncovers a reciprocal relationship between these niche cells and peripheral nerves, showing that disrupting nerve signals impairs bone marrow recovery after chemotherapy or radiation. His work also links retrotransposon activation during pregnancy to increased red blood cell production, with implications for maternal health and transplant medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40449]
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    54 分
  • Cellular Reprogramming in Human Disease

    Cellular Reprogramming in Human Disease
    2025/09/13
    Deepak Srivastava, MD, explores how cellular reprogramming offers new hope for treating heart disease. He highlights innovative strategies to regenerate damaged heart tissue by stimulating adult cardiomyocytes to divide and converting fibroblasts into heart-like cells. His team develops a nonviral delivery system using lipid nanoparticles and investigates the role of specific gene regulators in restoring heart function in animal models. Srivastava also discusses a potential oral therapy for aortic valve disease, driven by insights into cellular fate changes caused by NOTCH1 mutations and telomere shortening. Additionally, he reveals how trisomy 21 may trigger congenital heart defects by altering the identity of specialized heart cells. Through pioneering research in genetics and regenerative medicine, Srivastava demonstrates how understanding developmental biology can lead to transformative clinical advances. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40447]
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    58 分
  • Panic!: The Sound of Fury

    Panic!: The Sound of Fury
    2025/09/13
    Film historian Rebecca Prime joins moderator Ross Melnick (Film and Media Studies, UCSB) for a discussion of the classic Hollywood film The Sound of Fury. Prime outlines the film’s production history and how its political and social commentary was shaped by its director, Cy Endfield, who would go on to be blacklisted due to his association with the Communist Party. They further discuss Endfield’s subsequent work in London and how he struggled with the blacklist for the rest of his career. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40919]
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    34 分
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