Nels and Vincent examines the use of AI and genome language models to design novel derivatives of bacteriophage phiX174.

Hosts: Nels Elde and Vincent Racaniello

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• AI design of bacteriophage phiX174 derivatives (bioRxiv)
• Timestamps by Jolene

Nels – NIH official resigns after flap over risks of seasonal flu virus study and The Office of Science and Technology Policy (OSTP) requests input from all interested parties on Federal policy updates that aim to accelerate the American scientific enterprise, enable groundbreaking discoveries, and ensure that scientific progress and technological innovation benefit all Americans.
Vincent – One Plus One Equals One: Symbiosis and the evolution of complex life by John Archibald

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Nels and Vincent explain research which shows that insertion of a retrovirus into the genome regulates a novel color trait in swordtail fish.

Hosts: Nels Elde and Vincent Racaniello

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• Retrovirus and swordfish scale color (bioRxiv)
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Nels – Some like it hot! A geothermal amoeba sets a new upper temperature limit for eukaryotes and Kara Marshall's talk on history of science/science funding in the US, family connections to medical care, and her own lab's work at Baylor College of Medicine
Vincent – NIH shake-up to grant decision-making draws concerns of political meddling

Music on TWiEVO is performed by Trampled by Turtles

Send your evolution questions and comments to twievo@microbe.tv