The vial's Staphylococcus turned a vaccine into a killer
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The vial's Staphylococcus turned a vaccine into a killer
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The vial's Staphylococcus turned a vaccine into a killer
In this episode, we trace the morning of January 27, 1928, when a routine TAT diphtheria inoculation in Bundaberg sent children to their deaths and set off a national scientific and political response. How did a trusted vaccine become lethal, and where in the chain did the contamination occur?
Date: January 27, 1928
Location: Bundaberg, Queensland
Person: Dr. Ewing Thomson
Person: Macfarlane Burnet
Topic: TAT diphtheria inoculation contamination
- Twenty-one children attended the Bundaberg vaccination clinic that morning; eighteen collapsed the same afternoon.
- Dr. Ewing Thomson had been running inoculations since January 17 using a TAT serum from Commonwealth Serum Laboratories.
- The same batch of TAT was used in multiple towns but only caused illness in Bundaberg, suggesting contamination after manufacture.
- Macfarlane Burnet, aged twenty-nine, analyzed remaining serum and pus samples at the Walter and Eliza Hall Institute.
- Burnet detected Staphylococcus aureus in the Bundaberg vial and in pus from injection sites, pointing to a clinic-level bacterial contamination.
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