The temperature pill that slammed his throat shut and sparked a fever
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The temperature pill that slammed his throat shut and sparked a fever
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The temperature pill that slammed his throat shut and sparked a fever
In this episode, we follow the events inside Holmesburg Prison where routine medical care blurred into large-scale human testing and institutional secrecy. The episode traces how a single unguarded dose became entangled with an informal research program and raises the question of what accountability looked like inside those walls.
Location: Holmesburg Prison, 8215 Torresdale Avenue, Philadelphia
Person: Albert Kligman
Date: 1951 (Kligman first entered Holmesburg), 1947-1974 (period of experiments)
Program scale: 33 corporate and government sponsors; 80-90% of ~1,200 inmates used as subjects
Incident: Jerome Roach swallowed a "temperature pill" and developed throat closure, joint locking, fever, and sores
- Albert Kligman, a Penn dermatologist, first came to Holmesburg in 1951 to treat athlete's foot and then returned informally without written authorization.
- Kligman described the inmates as "acres of skin," framing the prison population as an available resource for dermatological testing.
- The testing program ran in a working city jail from the late 1940s to 1974 with dozens of outside sponsors paying to use inmates' bodies.
- Administrative separation meant experiments were recorded in a different system than routine prison medical care, so connections between treatments and adverse events were not documented.
- Jerome Roach swallowed a small "temperature pill" provided as part of a study, developed sudden throat closure on day four, then joint locking, fever, and sores, and was treated without records linking him to the experiment.
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