GLP-1s are peptides. The P literally stands for peptide. Your body makes its own GLP-1 after every single meal, and it's gone within a couple of minutes by design. The drugs are that same signal, engineered so it never goes away, and that one difference explains both how well they work and almost everything women struggle with on them.

In this episode I break it all down. What a peptide actually is, how peptide drugs are built, and what your own GLP-1 does in your body. Then how to raise your own GLP-1 with protein, soluble fiber, healthy fats, fermented foods, meal order and how fast you eat, with real meal ideas (and why fasting doesn't raise it the way people think).

Then I go drug by drug: semaglutide (Ozempic, Wegovy, Rybelsus), tirzepatide (Mounjaro, Zepbound), retatrutide, the new oral GLP-1 pill, and generic semaglutide here in Canada. We talk half-life and steady state, what the labels actually say about dosing, what microdosing really means, what's different for women (bone, muscle, fertility and hair loss), and what happens when you come off.

I start with a personal story too: I sliced my finger open this week, and how my meditation practice let me regulate my nervous system in the ER.

This is education, not medical advice. If you want to do this work with me, work with me one on one. I see women every week for peptides, nervous system, nutrition and longevity, and you can book a free 15 minute call with me here.

My free GLP-1 boosting recipe booklet for women is coming very soon. Subscribe to the podcast, my Substack, or follow me on Instagram so you hear when it drops.

I TALK ABOUT:

• 00:00 Slicing my finger, the ER, and regulating my nervous system in an emergency
• 08:50 Why my peptide content is moving off Instagram, and what's in this episode
• 10:10 What a peptide is, and how peptide drugs are built to last
• 17:34 Your own GLP-1: what it does, why it's gone in minutes, and food noise
• 26:30 Raising your own GLP-1: protein, fiber, fats, meal order, CGMs and meal ideas
• 44:54 Fasting and GLP-1
• 46:35 Half-life, steady state, and what happens when you stop
• 53:30 Semaglutide, tirzepatide, retatrutide, the new GLP-1 pill and generics in Canada
• 1:04:06 Dosing and microdosing
• 1:10:15 What's different for women: bone, muscle, fertility and hair
• 1:18:12 Coming off, side effects, and questions to ask yourself
• 1:22:09 Peptides in food, rhythm vs signal, and the close

RESOURCES:

• Work with me one on one
• Book a free 15 minute call with me
• The LongHer Life on Substack (where my peptide content lives now)
• The LongHer Life Online Community
• Instagram @biohackingbrittany

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice.

This is my live masterclass, The Exhale, from September. A few hundred women showed up live, and it's one of my favourite classes I've ever taught, so I'm giving you the whole thing here.

We go deep on peptides, longevity and the nervous system, and why the mind and nervous system have to come first before the body work and the advanced tools. I share my own postpartum anxiety story, the pattern I keep seeing in women, and why we can't out-peptide a dysregulated nervous system. Then I break down how cortisol shuts down growth hormone peptides, undoes gut peptides like BPC-157 and KPV, overrides sleep peptides, and why GLP-1s without protein, strength training and nervous system work put your muscle and bones at risk.

A note before you press play: about 18 minutes in there's a 12 minute guided future self activation, eyes closed. If you're driving, please don't close your eyes. Just listen, and come back to it when you can sit or lie down.

It ends with a full live Q&A: Retatrutide and microdosing, protein hacks and powders, MOTS-c and SS-31, creatine, BPC-157 and TB-500 for inflammation, glutathione, fasting, Kisspeptin before IVF, and labs.

If you want to do this work with me, work with me one on one. My three month program is open, I also do one off consultations, and you can book a free 15 minute call.

I TALK ABOUT:

• 00:00 Before you listen (and a note if you're driving)
• 03:21 Welcome to The Exhale
• 05:17 My postpartum anxiety story
• 09:13 Why nothing is sticking yet
• 16:18 Getting ready for the activation
• 17:55 Guided future self activation (12 min, eyes closed)
• 31:31 Coming back, and what came through
• 36:55 Fight or flight, rest and digest, and your HRV
• 39:32 Peptides and cortisol: growth hormone, gut health and sleep
• 48:09 GLP-1s, muscle, bone, and protein with peptides
• 57:18 Q&A: Retatrutide, protein, MOTS-c, creatine, BPC-157, Kisspeptin and labs
• 1:24:11 Becoming her, and the close

RESOURCES:

• Work with me: The Spark (my 12 week one on one program), a 60 minute consult, or a free 15 minute call
• The LongHer Life Longevity Community
• The LongHer Life on Substack
• Function Health, about $25 off with my link
• Instagram @biohackingbrittany

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice. Some links are affiliate links.

Part one was how to look like yourself again. Part two was how to feel like yourself again. Part three is who you actually are, and it's the one that decides whether any of it sticks.

I open with something heavy from this week: I can't talk about peptides on Instagram anymore. I had to archive about 20 posts, my TikTok was deleted, and I've been blocked from DMs for three days. So I talk about building on borrowed land, and where I can still speak freely.

Then the three women I meet over and over. The one who knows exactly what to do and still hasn't started. The one who changes for a few weeks and then life creeps in. And the one who's waiting to feel ready. I go into why willpower runs out, why it's cyclical and tied to your hormones, and the five days I took completely off this month while my HRV sat in the 80s.

Then what actually builds it: deciding who she is out loud instead of setting a goal, one decision a day that she would make, changing the inputs instead of the intentions, and refusing to do it alone. Plus the question I asked a client this week that stopped her cold: what does it cost you to feel like this for another year?

This is for education, not medical advice. If you want to do this work with me, The Spark is open, and there are three spots left. One on one, 12 weeks, future self activations plus labs, nutrition, protocols and peptides.

Join The LongHer Life Longevity Community for women-specific guidance on peptides, hormones, longevity and soul.

LISTEN TO THE FULL SERIES
Part 1, how to look like yourself again: https://biohackingbrittany.com/blogs/podcast/how-to-look-like-yourself-again
Part 2, how to feel like yourself again: https://biohackingbrittany.com/blogs/podcast/how-to-feel-like-yourself-again

TIMESTAMPS
00:00 Welcome back, and why I can't talk about peptides on Instagram
03:24 Building on borrowed land, and why email matters
05:59 Part 3 of 3: look, feel, and now be
06:56 The woman who knows exactly what to do
08:42 The woman who changes for a few weeks
09:57 Willpower is cyclical, and your hormones run it
11:11 The five days I took off, and what my HRV did
12:51 The woman who is waiting to feel ready
15:30 Decide who she is, out loud
17:06 One decision a day that she would make
22:30 Change the inputs, and stop doing it alone
25:12 The Spark, three spots left

Instagram and TikTok @biohackingbrittany
Shop everything I use at biohackingbrittany.com

This episode is for educational purposes only and is not medical advice.