Krutika Kuppali and Placide Mabala talk about the development control measures, diagnostic tests, and therapies for the current Bundibugyo outbreak in the Democratic Republic of the Congo.

The Lancet Infectious Diseases in conversation with... is part of the Lancet Group podcast offering.

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

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Fernando Tortosa and Ariel Izcovich discuss various aspects of hantavirus infections with a focus on the situation in Argentina, including transmission, epidemiology, clinical course, management, latest research developments, difficulties in conducting clinical trials, and future research priorities. The speakers also discuss the main findings and clinical implications of a study 'Use of tocilizumab for severe hantavirus pulmonary syndrome: a MEURI case series with contextual comparisons' they recently published in the journal.

Click here to read the full article:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00285-9/abstract

The Lancet Infectious Diseases in conversation with... is part of the Lancet Group podcast offering.

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering.

Find the best science for better lives at lancet.com Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Dr Brecht Ingelbeen and Dr Daniel Valia join Senior Editor Phoebe Hall to discuss a new trial in the journal (the CABU-EICO trial) testing a co-created behavioural intervention bundle to improve antibiotic use, patient management, and water, sanitation and hygiene in rural communities in Burkina Faso and DR Congo. They explain why the study focused on community prescribing (not hospitals), the primary endpoint was a reduction in WHO AWaRE Watch antibiotics (not overall antibiotics), and the intervention targeted all providers of antibiotics in the community, including informal vendors.

Finally, they discuss the importance of designing an intervention bundle that was truly tailored to local context yet practical, sustainable, and scalable beyond the study sites. A parallel study reporting the effect of the intervention bundle on ESBL-producing Escherichia coli colonisation (a co-primary outcome of the trial) is in press at The Lancet Microbe.

To read the full article:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00169-6/fulltext

The Lancet Infectious Diseases in conversation with... is part of the Lancet Group podcast offering.

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering.

Find the best science for better lives at lancet.com Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv