『The Future of Endometrial Cancer Therapeutics: Phase 3 Trials of ADCs and Beyond』のカバーアート

The Future of Endometrial Cancer Therapeutics: Phase 3 Trials of ADCs and Beyond

The Future of Endometrial Cancer Therapeutics: Phase 3 Trials of ADCs and Beyond

無料で聴く

ポッドキャストの詳細を見る
Drs Ursula Matulonis and Brian Slomovitz discuss phase 3 trials of ADCs in endometrial cancer and what's to come in the field of endometrial cancer therapeutics. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-endometrial-cancer-s3-ep1-2026a10006ib. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Endometrial Carcinoma https://emedicine.medscape.com/article/254083-overview B7 Homolog 4 (B7-H4)-Directed Agents in Oncology Clinical Trials: A Review https://pubmed.ncbi.nlm.nih.gov/40212845/ Efficacy and Safety of Trastuzumab Deruxtecan in Patients With HER2-Expressing Solid Tumors: Primary Results From the DESTINY-PanTumor02 Phase II Trial https://pubmed.ncbi.nlm.nih.gov/37870536/ Standardized Pathology Report for HER2 Testing in Compliance With 2023 ASCO/CAP Updates and 2023 ESMO Consensus Statements on HER2-Low Breast Cancer https://pubmed.ncbi.nlm.nih.gov/37770765/ Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01) https://clinicaltrials.gov/study/NCT07044336 Safety and Efficacy of Mirvetuximab Soravtansine, a Folate Receptor Alpha (FRα)-Targeting Antibody-Drug Conjugate (ADC), in Combination With Bevacizumab in Patients With Platinum-Resistant Ovarian Cancer https://pubmed.ncbi.nlm.nih.gov/36736157/ First in Human Study of IMGN151 in Recurrent Gynaecological Cancers https://clinicaltrials.gov/study/NCT05527184 DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer (DE-01) https://clinicaltrials.gov/study/NCT06989112 Pembrolizumab Plus Chemotherapy in Advanced or Recurrent Endometrial Cancer: Overall Survival and Exploratory Analyses of the NRG GY018 Phase 3 Randomized Trial https://pubmed.ncbi.nlm.nih.gov/40044930/ The GOG Highlight Reel July 2025 https://www.gog.org/wp-content/uploads/2025/08/GOG-Highlight-Reel-July-2025-Presentation-7.26.25.pdf Molecular Classification of Endometrial Cancer and Its Impact on Therapy Selection https://pubmed.ncbi.nlm.nih.gov/38892080/ Phase II Trial of Ribociclib Plus Letrozole in Women With Recurrent Low-Grade Serous Carcinoma of the Ovary, Fallopian Tube, or Peritoneum: A GOG Partners Trial (GOG 3026) https://pubmed.ncbi.nlm.nih.gov/41385758/ A Phase II Study of Frontline Paclitaxel/Carboplatin/Bevacizumab, Paclitaxel/Carboplatin/Temsirolimus, or Ixabepilone/Carboplatin/Bevacizumab in Advanced/Recurrent Endometrial Cancer https://pubmed.ncbi.nlm.nih.gov/29804638/ Mutated p53 Portends Improvement in Outcomes When Bevacizumab Is Combined With Chemotherapy in Advanced/Recurrent Endometrial Cancer: An NRG Oncology Study https://pubmed.ncbi.nlm.nih.gov/33541735/ Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer https://clinicaltrials.gov/study/NCT07198074 WEE1 Inhibitor: Clinical Development https://pubmed.ncbi.nlm.nih.gov/34269904/ Palbociclib Plus Letrozole in Estrogen Receptor-Positive Advanced/Recurrent Endometrial Cancer: Double-Blind Placebo-Controlled Randomized Phase II ENGOT-EN3/PALEO Trial https://pubmed.ncbi.nlm.nih.gov/39657575/ GOG3069: Phase 2 Study of Alpelisib and Fulvestrant for PIK3CA-Mutated Estrogen Receptor (ER)-Positive Endometrioid Endometrial Cancers https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.TPS5639 TP004/#1561 A Phase 2, Open-Label, Single-Arm, Prospective, Multicenter Study of Nab-Sirolimus Plus Letrozole in Advanced or Recurrent Endometrioid Endometrial Cancer https://www.sciencedirect.com/science/article/pii/S1048891X24163530 Repositioning GLP-1 Receptor Agonists in Endometrial Cancer: Molecular Rationale, Preclinical Insights, and Translational Opportunities https://pubmed.ncbi.nlm.nih.gov/41329840/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
adbl_web_anon_alc_button_suppression_c
まだレビューはありません