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AGEIST

AGEIST

著者： David Stewart
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The AGEIST podcast is where we rewrite life after 50. Hosted by David Stewart, founder of AGEIST and Super Age, we talk with extraordinary people—scientists, creatives, and thinkers—about living vibrantly in your 50s, 60s, 70s and beyond. From longevity science to emotional well-being, fitness to purpose, we explore the tools and mindsets that help us stay curious, energized, and deeply engaged with life. This isn’t about aging gracefully—it’s about living boldly.

© 2026 AGEIST 個人的成功 自己啓発
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  • Dr. Christin Glorioso: Keep The Brain Young

    Dr. Christin Glorioso: Keep The Brain Young
    2026/10/29
    Dr. Christin Glorioso knows the dread many people carry about their own memory, the invisible weight of wondering what the last decade of life will look like and whether their wits will come along. She watched Alzheimer’s disease take both her grandmother and her aunt. As a physician and neuroscientist with one copy of the APOE4 gene, she explains why her research at MIT convinced her that slowing biological brain aging by five years makes Alzheimer’s six times less likely, and why she believes about half of cases are preventable even with genetic risk. She walks through the nine pillars of healthy brain aging she follows herself, from a green Mediterranean diet with duckweed smoothies to high intensity training intervals that appear to help the hippocampus, and describes how her company NeuroAge Therapeutics pairs a brain aging test with their long term goal of developing pharmaceutical drugs. Not sure where to start? Take their test and pick the pillar you are doing worst in. Build new habits to improve that pillar and go from there.Special Thanks to Our SponsorsBEAM Minerals: Plant-based liquid minerals for replenishing the foundational compounds your body needs to age well. Listeners can now get 20% off their first BEAM purchase by using the code “AGEIST” at checkout at BeamMinerals.com/ageist.Key Moments“So there’s this huge actionable piece which has been really empowering.”“You can grow your brain back, just like you can make your muscles bigger.”“So your parents told you video games will rot your brain. Not true. It’s actually pretty good for you.”Connect with Dr. Christin GloriosoNeuroAge Therapeutics: https://www.neuroagetx.comYounger contest: https://www.neuroagetx.com/events/youngerNeuroGames: https://app.neuroagetx.com/Substack: https://drglorioso.substack.comLinkedIn: https://www.linkedin.com/in/christin-glorioso-md-phd-39627719/X: https://x.com/DrGloriosoNeuroAge on Instagram: https://www.instagram.com/neuroage_therapeutics/NeuroAge on LinkedIn: https://www.linkedin.com/company/neuroage-therapeutics/Connect with AGEISTNewsletter: https://www.ageist.com/newsletter/Instagram: https://www.instagram.com/weareageist/Website: https://www.ageist.comLinkedIn: https://www.linkedin.com/company/ageistClick Here for the full interview transcript.Dr. Christin Glorioso and the Case for Training Your Brain Like a MuscleGlorioso reads brain scans for a living, and she says what shows up on an MRI tends to mirror what a person neglects. A shrinking cerebellum, the balance center at the back of the brain, usually points to someone who rarely does anything that challenges their balance. A hippocampus that is losing volume faster than expected, the memory region hit hardest by Alzheimer’s disease, responds to high intensity intervals. Her recommendation is two interval sessions a week, with the Norwegian four by four as the classic template: four minutes at roughly 80 to 90 percent of maximum heart rate, three minutes of easy effort, repeated four times. She cites a randomized trial in which balance training enlarged the cerebellum, and she reports that her own hippocampus has grown slightly over the past year and a half.Reaction Time, Video Games, and Mental EffortThe mental activity pillar offers some unexpected advice. Glorioso points to a ten year randomized trial in which a game that trains reaction speed lowered later dementia risk by about 30 percent, and she plays a similar game for ten minutes a day. She adds that large cohorts such as the UK Biobank show roughly 20 percent less dementia risk among people who play more video games, and that pickleball or ping pong can train the same quick responses. The common thread is difficulty. Time on a hobby counts only when it demands real effort rather than autopilot.The Overlooked Link Between Heart and BrainGlorioso also explains why cardiovascular health belongs in any conversation about memory. Vascular dementia, the second most common form after Alzheimer’s, comes from small blockages that cause tiny strokes in the brain, and the two conditions often overlap. Her own APOE4 variant affects how cholesterol is transported, which gave her borderline high cholesterol even as a college tennis player. She now takes a statin, and she tells listeners that anyone who needs one should not leave it untreated.Choosing Where to StartFor anyone overwhelmed by nine pillars, she suggests a four minute lifestyle quiz on the NeuroAge site and then working on the area where you score lowest. Habits make the rest easier, she says, which is why her Monday evening exercise class never requires a decision. She once tracked her daily list on a wall calendar with shiny stickers, covering the duckweed smoothie, twenty minutes of sunshine, and an hour of exercise, and she says the sum of those small tweaks matters more than any single one.Tune in to hear more on this episode of The AGEIST Podcast or check out the full interview transcript.Say hi to the...
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    37 分
  • Caroline Alan: The Longevity Role of Minerals

    Caroline Alan: The Longevity Role of Minerals
    2026/10/15

    Caroline Alan spent years hearing from practitioners that her exhaustion, insomnia, and inflammation were simply part of getting older, until a cup of dark liquid from her future business partner led her to ask whether aging and depletion might be the same thing. In this conversation, the co-founder and CEO of BEAM Minerals and author of The Mineral Reset explains why she believes generations of farming have left soil unable to return minerals to our food, and why humic and fulvic minerals, which come from decomposed ancient rainforests, work in a way a shelf of eighteen separate pills cannot. She also lays out how minerals fuel the mitochondria in every cell, why their number and activity decline with age, and why she considers mineral balance as important as quantity. Listeners will hear her timeline for when people tend to notice changes in energy, recovery, and sleep, along with the symptoms she says are easy to overlook.

    Special Thanks to Our Sponsor

    BEAM Minerals: Plant-based liquid minerals for replenishing the foundational compounds your body needs to age well. Listeners can now get 20% off their first BEAM purchase by using the code “AGEIST” at checkout at BeamMinerals.com/ageist.

    Key Moments

    “We’ve been treating our soils like a bad bank account where we just keep taking money out, withdrawal, withdrawal, withdrawal, and our soils are depleted.”

    “You’ve got all these symptoms, and the symptoms are like boats on the sand. And when the tide comes in, they all raise off the sand at the same time.”

    “My light bulb just burns brighter now. It was way dimmed down 10 years ago.”

    Connect with Caroline Alan

    Website: https://mineralgeek.com
    BEAM Minerals: https://www.beamminerals.com
    Instagram: https://www.instagram.com/carolinealan.official
    TikTok: https://www.tiktok.com/@carolinealan.official
    Find out if you are mineral deficient - https://quiz.mineralresetbook.com/

    Get "The Mineral Reset" - mineralresetbook.com

    Connect with AGEIST

    Newsletter

    Instagram

    Website

    LinkedIn

    Click Here for the full interview transcript.

    Say hi to the AGEIST team!
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    40 分
  • Dr. Jeffrey Bland: An Ancient Grain He Found By Accident

    Dr. Jeffrey Bland: An Ancient Grain He Found By Accident
    2026/10/01

    Dr. Jeffrey Bland, 80, draws a sharp line between being elderly and being an elder: one has lost function and become dependent, the other stays wise, capable, and still contributing to the people around them. In this conversation, Dr. Bland explains why he's built his current company, Big Bold Health, around the immune system, since it's the one system embedded in every tissue in the body and central to how we age at the cellular level. The researcher credited with coining the term functional medicine back in 1990 shares results from an 800-person clinical trial on Himalayan Tartary Buckwheat. An ancient Chinese grain his team stumbled into almost by accident, this superfood improved cognitive performance by 27 percent in just 90 days by reprogramming the epigenetic markers on immune cells. Listeners will come away with a clearer picture of how diet, environment, and daily habits can switch specific genes on or off, and why the goal of longevity isn't just more years, but more years spent as the version of yourself still capable of contributing.

    Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

    Special Thanks to Our Sponsors

    Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

    LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

    Key Moments

    "Nature will give over her secrets."

    "Elders are individuals that are wise, that are still functional, still making contributions, still being part of the productive society."

    "We make over one million new immune cells every second."

    Connect with Dr. Jeffrey Bland

    Website

    Big Bold Health

    The Disease Delusion

    LinkedIn

    Instagram

    Facebook

    Connect with AGEIST

    Newsletter

    Instagram

    Website

    LinkedIn

    Click Here for the full interview transcript.

    Say hi to the AGEIST team!
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    55 分
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