Tanay Tandon on Agents in RCM, Nikhil Krishnan, and Fat Cells That Remember | HCN Ep. 10
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Tanay Tandon on Agents in RCM, Nikhil Krishnan, and Fat Cells That Remember | HCN Ep. 10
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Can fat cells remember obesity, and are systems of agents about to take over healthcare administration? This week on HCN, Cedric Kovacs-Johnson and Danish Nagda dig into a suspected plague scare in Russia, a Nature paper on fat cell memory, and this year's Nobel for optogenetics. Tanay Tandon, CEO of COMMURE, joins to explain how AI agents could reshape revenue cycle and payer fights. Nikhil Krishnan, Founder/Thinkboi at Out-of-Pocket, shares who is building healthcare companies now and why he's optimistic.
00:00 — Bookmarks: The Best Things We Found This Week
Cedric and Danish share favorite finds: Bjork on creating for yourself, crypto-style investors piling into AI biotech, a debate over late doctors, and Dave Ricks on placebo-controlled GLP-1 trials.
07:46 — The Plague: Mystery Death at a Russian Anti-Plague Lab
A young employee of a Siberian anti-plague institute died after severe pneumonia, with a lab exposure unconfirmed. Danish explains how plague works, how it's treated, and why it's worth watching.
13:59 — Tanay Tandon: Are Systems of Agents Taking Over Healthcare?
COMMURE's CEO explains its system of agents, why it targets non-Epic settings, and why he sees AI-versus-AI payer disputes as an arms race that ends in efficiency. Cedric and Danish push back and probe.
30:17 — Fat Epigenetics: Cells That Remember Obesity
Danish walks through a Nature paper suggesting fat cells keep epigenetic changes after weight loss, which could make keeping weight off harder, and the hosts discuss childhood obesity and what might reverse it.
38:32 — Nikhil Krishnan: Who's Building the Future of Healthcare?
The Out-of-Pocket founder discusses the new founder archetype, why funding rounds are growing, whether AI success is stuck in RCM, financing ideas, a healthcare World's Fair, and his optimism.
57:11 — Nobel Prize: Optogenetics and the Brain as a Circuit
Karl Deisseroth, Peter Hegemann and Georg Nagel win the Nobel for optogenetics. Danish explains the light-switch method and why he sees it as a precise tool for studying the brain, before the hosts close on optimism.