エピソード

  • TSC Talks 3.0 (not) Research ~ In the Stone Chamber

    TSC Talks 3.0 (not) Research ~ In the Stone Chamber
    2026/05/06
    Taking a break from the harsh closed loops and hunkering down in dis stone chamber to give a little freestyle riff for this episode from the stone chamber
    no links
    except go watch the video. the audio just won't cut it on this one
    https://youtu.be/bEIqg2lcDU0

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    3 分
  • TSC Talks 3.0 Research~Episode 10

    TSC Talks 3.0 Research~Episode 10
    2026/04/29
    I bust through the third wall or whatevs in Episode 10 of TSC Talks 3.0 Research. Dropped the whiteboard til the end. Summed up the 9 episodes and added a bit on the end about CPTSD, TAND and the fact that the entire family system is drawn into the grid as data churnin' emotin' node. Used the Google AI to investigate the theories I had on amplification of TSC by multiple factors for purpose and product and it proved true based on the research plus lived experience thus far.

    Source Links for Further Research
    I. Rare Disease Advocacy and Funding (Conflicts of Interest)
    [TSC Alliance: Corporate Policies](https://www.tscalliance.org/about-tsc/corporate-policies/)
    [TSC Alliance: COVID-19 Vaccine Position Statement](https://www.tscalliance.org/wp-content/uploads/2021/08/TSC-Alliance-COVID-19-Vaccine-Position-Statement-Update-August-2021-FINAL.pdf)
    [TSC Alliance: Phenotypic Variability Research](https://www.tscalliance.org/tsc-matters/phenotypic-variability-in-tuberous-sclerosis-complex-tsc/)
    [TSC Alliance: 2024 Talking Points](https://www.tscalliance.org/wp-content/uploads/2024/01/2024-Talking-Points-Final.pdf)
    [NORD: Mission and Values](https://rarediseases.org/about-us/mission-values/)
    [NORD: Research Grant Programs](https://rarediseases.org/advancing-research/research-grant-programs/)
    [EURORDIS: Our Funding](https://www.eurordis.org/who-we-are/our-funding/)
    [Mass General: Herscot $50 Million Gift](https://giving.massgeneral.org/stories/herscots-make-50-million-gift-to-mass-general)
    [NEJM: Industry Support for Patient Advocacy](https://www.nejm.org/doi/full/10.1056/NEJMsr1610625)
    II. Gene Therapy (CRISPR), Risks, and Regulation
    [FDA: Cellular & Gene Therapy Products](https://www.fda.gov/vaccines-blood-biologics/cellular-gene-therapy-products)
    [CRISPR-Cas9 Off-Target Effects (Synthego)](https://www.synthego.com/blog/crispr-off-target-editing/)
    [CRISPR: Genome Engineering Advantages and Limitations (Taconic)](https://www.taconic.com/resources/crispr-genome-engineering-advantages-limitations)
    [FDA: Regulatory Distinctions for Cell and Gene Therapies (LinkedIn)](https://www.linkedin.com/pulse/fda-vs-ema-key-regulatory-distinctions-cell-gene-therapies-ywzye) [Informed Consent and Clinical Trials (PMC)](https://pmc.ncbi.nlm.nih.gov/articles/PMC2659702/) [Immune Evasion in Engineered CRISPR Enzymes (Broad Institute)](https://www.broadinstitute.org/news/scientists-engineer-crispr-enzymes-evade-immune-system) [The Ethics of Gene Editing (Innovative Genomics)](https://innovativegenomics.org/crisprpedia/crispr-ethics/)
    III. Vaccines, Toxins, and Environmental Amplification
    [TSC Drug Market & Prevalence (OpenPR)](https://www.openpr.com/news/3536609/tuberous-sclerosis-complex-drug-market-2034-epidemiology)
    [Vaccines and the Rise in Pediatric Cancer (The Vaccine Reaction)](https://thevaccinereaction.org/2018/05/is-there-a-link-between-vaccines-and-the-rise-in-pediatric-cancer/)
    [Study of Vaccinated and Unvaccinated Children (Weston A. Price)](https://www.westonaprice.org/health-topics/vaccinations/chronic-disease-a-study-of-vaccinated-and-unvaccinated-children/#gsc.tab=0)
    [Role of Environmental Toxins in Epigenetic Dysregulation (PLM Institute)](https://plminstitute.org/plmi-blog/the-role-of-environmental-toxins-in-epigenetic-dysregulation/) [Childhood Vaccination Schedule Explosion (Twitter - NVICLoeDown)](https://twitter.com/NVICLoeDown/status/1687176816774033408) [COVID-19 Vaccine Added to Childhood Schedule (Children's Health Defense)](https://childrenshealthdefense.org/defender/childhood-covid-vaccine-schedule/) [The Role of Environmental Exposures in Genetic Disease (PMC)](https://pmc.ncbi.nlm.nih.gov/articles/PMC4021822/)
    IV. Alternative and Holistic Approaches
    [Ketogenic Diet Inhibits the mTOR Pathway (AESnet)](https://aesnet.org/abstractslisting/the-ketogenic-diet-inhibits-the-mammalian-target-of-rapamycin-\(mtor\)-pathway)
    [Ketogenic Diet for Epilepsy in TSC (PMC)](https://pmc.ncbi.nlm.nih.gov/articles/PMC5540690/) [Curcumin Inhibits mTOR Activity (ScienceDirect)](https://www.sciencedirect.com/science/article/abs/pii/S0944711318304860)
    [Natural Treatment for TSC (Inspire Forum)](https://www.inspire.com/groups/tuberous-sclerosis-complex/discussion/natural-treatment-for-tsc/)
    [Natural Products and Patenting (PMC)](https://pmc.ncbi.nlm.nih.gov/articles/PMC8521639/) [Anti-Inflammatory Living (Holistic Health Code)](https://www.holistichealthcode.com/articles/unlocking-metabolic-health)
    contact Jill: pjlacy6@gmail.com

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    36 分
  • TSC Talks 3.0 Research~Episode 9

    TSC Talks 3.0 Research~Episode 9
    2026/04/22
    In this episode, I get into mitigation strategies related to the increasing reliance on tech with the arrival of 6G particularly for those living with a chronic and or rare disease that is on multiple medications and dependent on the grid. What would be considered alternative or holistic therapies such as grounding, sound therapy, ketogenic diet and exercise have all been proven to help support the full field in finding homeostasis even with a condition such as TSC and can improve overall health and quality of life as a support beyond meds and other more drastic regimens. I also talk about the similarities between CPTSD and TAND (TSC Associated Neuropsychiatric Disorder) and the importance of understanding the "energetics" of a rare disease when advocating for one's self and/or loved ones. The system will add additional labels and complicate understanding. I hope to explore further the CPTSD connection as I feel it as AS relevant as the limited focus of TAND.

    Full list of links: https://docs.google.com/document/d/e/2PACX-1vQv_yBMqtFvxQmhm31TXozv20_nEGxCTwjUCclYrEK2yE9NGR6rQqc1GyMsA76lUNtNrZda-FF_Z2IM/pub


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    36 分
  • TSC Talks 3.0 Research~Episode 8

    TSC Talks 3.0 Research~Episode 8
    2026/04/15
    Episode 8 of TSC Talks 3.0 Research... continuing on with the extensive history of the rare disease Tuberous Sclerosis Complex, the set up for data harvesting and gene editing and the inevitability of enhanced grid adhesion. Woohoo! Next episode I'm gonna go into mitigation and the upswing of the sitch. Links:mindandbodyexercises.comhttps://medium.comhttps://maescenter.comrockarch.orgtikvahhealthandwellness.comnih.govnih.govnutritiondiagnostics.com.aunih.govpsychologytoday.comnih.govmcgill.cachop.eduhttps://historyofvaccines.orgnih.govjpeds.comhttps://time.comnih.govnih.govnih.gov2minutemedicine.comnih.govnih.govsciencedirect.comnih.govcdc.govnih.govhttps://richd.orgnih.govwikipedia.orgempr.comhttps://historyofvaccines.orghttps://drgreenmom.commayoclinic.orgkaiserpermanente.orgnih.govkff.orgforbes.comitu.intciocoverage.comhttps://studyfinds.orgBecome a supporter of this podcast: https://www.spreaker.com/podcast/tsc-talks--1666046/support.
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    30 分
  • TSC Talks 3.0 Research~Episode 7

    TSC Talks 3.0 Research~Episode 7
    2026/04/08
    The history of Tuberous Sclerosis Complex.
    they're juicing it.
    Some queries related to the complexity of epigenetic variables and the overlords decision to focus on genetics only for the sake of "simplicity"...
    Just my opinion?
    I welcome all listeners and critical thinkers.
    📚 Primary Research & Databases PubMed Central (Full-Text Archive): https://pmc.ncbi.nlm.nih.gov
    PubMed (Citations & Abstracts): https://pubmed.ncbi.nlm.nih.gov
    ScienceDirect: sciencedirect.com
    Wiley Online Library: https://onlinelibrary.wiley.com
    Springer Link: https://link.springer.com
    ResearchGate: researchgate.net Academia.edu: academia.edu
    🏥 Health Organizations & Agencies NIH / National Library of Medicine: https://www.ncbi.nlm.nih.gov
    NINDS (Neurological Disorders): https://www.ninds.nih.gov
    MedlinePlus: https://medlineplus.gov
    HRSA (Health Resources): hrsa.gov
    Texas Children’s Hospital: texaschildrens.org
    TSC Alliance: tscalliance.org
    Epilepsy Foundation: epilepsy.com
    🔬 Specialized Medical Journals
    The Lancet: thelancet.com Pediatric Neurology: pedneur.com
    Neurotherapeutics: neurotherapeuticsjournal.org
    Frontiers in Science: frontiersin.org eLife Sciences: https://elifesciences.org
    AMA Journal of Ethics: ama-assn.org
    AAP Publications: aap.org ACR Journals: https://acrjournals.onlinelibrary.wiley.com
    ACR Abstracts: https://acrabstracts.org
    2 Minute Medicine: https://www.2minutemedicine.com
    📰 News, Legal & Historical Context
    TIME Magazine: https://time.com
    Medical Xpress: https://medicalxpress.com
    History of Vaccines: https://historyofvaccines.org
    Texas Vaccine Lawyers: texasvaccinelawyers.com
    Digital Commons (Rockefeller): rockefeller.edu HealthCentral: healthcentral.com Changing Aging: https://changingaging.org
    Medium: https://medium.com
    Meridian Health Clinic: https://meridianhealthclinic.com
    Wikipedia: wikipedia.org WikiDoc: wikidoc.org
    contact Jill ~ pjlacy6@gmail.com

    Become a supporter of this podcast: https://www.spreaker.com/podcast/tsc-talks--1666046/support.
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    34 分
  • TSC Talks 3.0 Research~Episode 6

    TSC Talks 3.0 Research~Episode 6
    2026/04/01
    In Episode 6 of TSC Talks Research 3.0, I finish up the discussion of CRISPR and TSC and the trajectory, I get into cannabis and the way they've deglimmered exploration of consciousness for those with rare diseases on hefty meds and how this relates to the cultivated biosphere that limits the full potential of the divine human. So many the templates for data and experimentation to build the current Healthcare 4.0 system and Precision Medicine. While many will be helped, there will be a dependence on the grid system.
    YouTube Video: https://youtu.be/OqLKIZ7Q54s?si=8svWmKHp4ekiFOnR
    Links: https://www.liebertpub.com/doi/10.1089/crispr.2024.0079
    https://pubmed.ncbi.nlm.nih.gov/39654514/
    https://pediatricsnationwide.org/2024/01/11/innovative-gene-therapy-approach-for-treating-patients-with-tuberous-sclerosis-type-2/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7793581/
    https://innovativegenomics.org/news/crispr-clinical-trials-2026/ https://frontlinegenomics.com/sickle-cell-disease-a-2024-update/ epidiolexhcp.com
    nih.gov
    sciencedaily.com
    https://www.researchgate.net/publication/348347376_Gene_therapy_for_tuberous_sclerosis_complex_type_2_in_a_mouse_model_by_delivery_of_AAV9_encoding_a_condensed_form_of_tuberin globalgenes.org neurologylive.com berkeley.edu ccf.org

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    32 分
  • TSC Talks 3.0 Research~Episode 5

    TSC Talks 3.0 Research~Episode 5
    2026/03/25
    In this episode I share information on the risks and side effects of CRISPR for individuals with TSC and in general as well as go into how those affected with TSC are "test bunnies" for much of this new technology, and my theories with documentation of why this is happening. I also go over some of the "no touch" technologies being rolled out and tested on those with diseases such as TSC where the nature of the genetics, a "monogenic" disorder, makes it a more suitable population to experiment on to gain information than other more common disorders, such as Alzheimer's, which involve 100s of genetic factors. TSC population is kept in that "test bunny" role without ever addressing the external factors that make the disease more difficult to manage in the first place.LINKS:pmc.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC7672342/https://cdmrp.health.mil/tscrp/defaulthttp://tuberous-sclerosis.org/research/tsa-funded-research/https://www.mdpi.com/2075-1729/15/3/368https://www.tscalliance.org/wp-content/uploads/2023/02/Training-Packet-Documents.pdfhttps://pmc.ncbi.nlm.nih.gov/articles/PMC3010088/https://pmc.ncbi.nlm.nih.gov/articles/PMC4527140/https://pubmed.ncbi.nlm.nih.gov/19028034/https://pmc.ncbi.nlm.nih.gov/articles/PMC6851053/https://www.youtube.com/watch?v=hXRRq-dFuYghttps://www.youtube.com/watch?v=Hu2TvhhdEHYhttps://www.youtube.com/watch?v=BFuXttZspaYhttps://pmc.ncbi.nlm.nih.gov/articles/PMC5727703/https://globalgenes.org/raredaily/transforming-tsc-epilepsy-with-a-precision-therapy/https://pediatricsnationwide.org/2024/01/11/innovative-gene-therapy-approach-for-treating-patients-with-tuberous-sclerosis-type-2/https://pmc.ncbi.nlm.nih.gov/articles/PMC3164024/https://pmc.ncbi.nlm.nih.gov/articles/PMC11944049/https://www.biorxiv.org/content/10.1101/2024.02.22.581652v1.full-texthttps://pmc.ncbi.nlm.nih.gov/articles/PMC6408922/https://www.mdpi.com/2076-3417/14/3/1132https://pmc.ncbi.nlm.nih.gov/articles/PMC3744999/https://www.researchgate.net/publication/24217930_Magnetically_Responsive_Nanoparticles_for_Drug_Delivery_Applications_Using_Low_Magnetic_Field_Strengthshttps://pmc.ncbi.nlm.nih.gov/articles/PMC2933363/https://pmc.ncbi.nlm.nih.gov/articles/PMC7998448/https://pmc.ncbi.nlm.nih.gov/articles/PMC9230665/Become a supporter of this podcast: https://www.spreaker.com/podcast/tsc-talks--1666046/support.
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    29 分
  • TSC Talks 3.0 Research~Episode 4

    TSC Talks 3.0 Research~Episode 4
    2026/03/18
    TSC Talks 3.0 Research, Episode 4Here's my ongoing convo with AI delving into the funding behind rare disease research, non profits and how there are vested interests in continuing to bypass the full range of knowledge about what impacts the genome such as environmental (vaccines included) amplifications so they can justify the need for gene therapy via crispr, etchttps://rarediseases.org/about-us/financials-governance/https://rarediseases.org/collection/nord-financials/https://rarediseases.org/nord-releases-report-on-the-state-of-rare-disease-diagnosis-care-and-treatment-in-america-over-three-decades/https://rarediseases.org/nord-state-report-card/rarediseases.orghttps://rarediseases.org/wp-content/uploads/2022/10/NORD_2020_Annual-Report_wFinancials.pdfhttps://rarediseases.org/wp-content/uploads/2022/01/NORD_2020_Annual-Report_FINAL_SpreadView_web.pdfhttps://rarediseases.org/wp-content/uploads/2022/10/NRD-1198-2019_Annual-Report_FNL_WebSize.pdfhttps://www.eurordis.org/who-we-are/our-funding/https://www.eurordis.org/who-we-are/projects-and-partnerships/https://www.eurordis.org/partnerships/https://www.eurordis.org/get-involved/join-the-eurordis-round-table-of-companies/https://www.eurordis.org/publications/eurordis-policy-on-financial-support-by-commercial-companies-2/https://www.eurordis.org/our-priorities/research/https://www.eurordis.org/eurordis-supports-member-states-efforts-operating-grants-reintroduction/https://www.eurordis.org/videos/rare-but-real-talking-rare-diseases-part-1-6/download2.eurordis.orgvzacna-onemocneni.czhttps://everylifefoundation.org/rare-hub/rare-hub-partners-current-1-3/https://everylifefoundation.org/financial-support/https://everylifefoundation.org/everylifeeveryaction/https://everylifefoundation.org/sitemap/https://everylifefoundation.org/wp-content/uploads/2025/08/ELF-AnnualReport-2024-8.5x11-Proof-v6-081225.pdfhttps://everylifefoundation.org/wp-content/uploads/2022/01/Guide-to-Patient-Involvement-FINAL-COMPLETE-GUIDE-Rev.pdfhttps://everylifefoundation.org/wp-content/uploads/2016/05/Industry-Brochure-FINAL-May-2016.pdfBecome a supporter of this podcast: https://www.spreaker.com/podcast/tsc-talks--1666046/support.
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    30 分