In this exclusive podcast interview, Denise Holt sits down with Brett Kagan, Chief Scientist at Cortical Labs, for an in-depth exploration into their groundbreaking synthetic biological intelligence (SBI) technology. Brett reveals the science behind their revolutionary CL1 system—the first commercial biological computer fusing live human neurons with silicon computing. We discuss how their DishBrain experiment validated Dr. Karl Friston's Free Energy Principle, the extraordinary energy efficiency of biological intelligence, and the significant implications for industries like drug discovery, personalized medicine, and robotics. Don't miss this insightful conversation, rich with first-hand stories and detailed explanations from the forefront of neuroscience and AI innovation. #CorticalLabs #CL1 #ActiveInferenceAI

Key Topics:

· The CL1 System: How Cortical Labs successfully merged live human neurons with silicon chips to create the first synthetic biological intelligence computing system.

· DishBrain Experiment: Insights into the groundbreaking experiment validating Dr. Karl Friston's Free Energy Principle through neuron-based Pong gameplay.

· Energy Efficiency of Biological Intelligence: Understanding how biological neurons provide vastly superior energy efficiency compared to traditional AI systems.

· Ethical Implications: Brett Kagan's candid discussion on the responsible use of human neurons in research and their potential to reduce animal testing.

· Real-world Applications: The transformative impact of synthetic biological intelligence on drug discovery, personalized medicine, and robotics.

Guest:Brett Kagan, Chief Scientific Officer at Cortical Labs
Host: Denise Holt, CEO and Founder, AIX Global Media

Huge thank you to Brettfor being on our show!

Discover more about Cortical Labs: https://corticallabs.com

Looking for education resources and courses on Active Inference, the Free Energy Principle, and Spatial Web Technologies? Visit Learning Lab Central to find others around the world who are just as excited for this new shift in AI and computing:

https://learninglab.emmersionpublishing.com

#CorticalLabs #CL1 #FreeEnergyPrinciple#ActiveInferenceAi

In this special episode of the Spatial Web AI Podcast,Denise Holt reconnects with Katryna Dow, CEO and Founder of Meeco, exactly 10years after their first conversation on Denise's earlier podcast, CollaborativeIQ. That original episode, "Let's Talk: Retaining Ownership of YourPersonal Data | Interview: Katryna Dow of Meeco," aired on March 31, 2015,and addressed early concerns about data privacy and individual data ownership.#dataprivacy #SpatialWeb

A decade later, Katryna, one of the earliest pioneerstackling data privacy and personal digital identity, reflects on how herinitial warnings about data misuse have unfolded and intensified. Having foreshadowedevents like the Cambridge Analytica scandal years ahead of time, she now highlightstechnological advances and shifts toward decentralized systems, the criticalrole of cryptography, decentralized identity, zero-trust architectures, and howthese elements are reshaping our digital lives. Katryna also shares recentmilestones at Meeco, including impactful collaborations across Europe,Australia, and Japan, and explores the emerging implications of AI, digitaltwinning, and the Spatial Web Protocol for privacy, trust, and secure digitalinteractions.

Join this timely discussion to gain valuable insights intohow far we've come, the evolving challenges of data privacy, and the essentialsteps toward building a secure, transparent, and user-controlled digitalfuture.

As a bonus to those who are curious about what we werediscussing ten years ago, the audio of the original interview is attached tothe end of our current conversation.

Topics Covered:

Evolution of Data Privacy (2015-2025)

Transitioning from Centralized toDecentralized Architectures

AI, Digital Identity, and PredictiveAnalytics

Regulatory Impacts: GDPR, EU DigitalIdentity, and Global Developments

The Role of Emerging Technologies andthe Spatial Web Protocol

Trust, Transparency, and DigitalEthics in the Next Decade

Guest: Katryna Dow, CEO and Founder of Meeco
Host: Denise Holt, CEO and Founder, AIX Global Media

Huge thank you to Katrynafor being on our show!

Katryna Dow onLinkedIn: https://www.linkedin.com/in/katrynadow/

Tolearn more about data privacy infrastructure, visit Meeco at https://www.meeco.me/

To find out moreabout Learning Lab Central and education and courses offered on ActiveInference AI and Spatial Web Technologies, visit:

https://emmersionpublishing.com/

To find others aroundthe world who are just as excited for this new shift in AI and computing, visitLearning Lab Central community platform:

https://learninglab.emmersionpublishing.com

#dataprivacy #SpatialWeb #Decentralization

January 28, 2025 - In this episode of the Spatial Web AI Podcast, titled "Active Inference AI - The AI Paradigm Shift Dr. David Bray, PhD Wants You to Know About," host Denise Holt engages in a thought-provoking conversation with Dr. David Bray, a distinguished figure renowned for his deep understanding of technology and geopolitics.

Dr. Bray, heralded as one of the 24 Americans changing the world by Business Insider and a former CIO of the FCC, shares his insights on the transformative potential of Active Inference AI. He contrasts this emerging technology with the limitations of current generative AI models, emphasizing Active Inference’s ability to reduce uncertainty and enhance system trustworthiness.

Throughout the discussion, Dr. Bray articulates the necessity for a shift in our technological frameworks to accommodate the energy-efficient and adaptable capabilities of Active Inference AI. He emphasizes how this evolution in AI can enhance human agency and ensure the sustainability of societal advancements. Watch this episode to understand why Active Inference AI is not just a technological upgrade but a critical evolution for the integration of AI into our lives and societal structures.

Huge thank you to Dr. Bray for being on our show!

Dr. David Bray, PhD on LinkedIn: https://www.linkedin.com/in/dbray/

To find out more about Learning Lab Central and education and courses offered on Active Inference AI and Spatial Web Technologies, visit:

https://emmersionpublishing.com/

To find others around the world who are just as excited for this new shift in AI and computing, visit Learning Lab Central community platform:

https://learninglab.emmersionpublishing.com

#ActiveInferenceAI #SpatialWeb #KarlFriston #VERSESAI

The Spatial Web: A New Dimension of the Internet and a Technological Awakening for AI | Exclusive Interview with Denise Holt on August 22, 2024 #SpatialWeb #ActiveInferenceAI #HSML

In this exclusive interview and presentation, Denise Holt, founder of AIX Global Media, and leading educator in Active Inference AI and Spatial Web Technologies, discusses the groundbreaking evolution of the Internet into the Spatial Web and the transformative power of Active Inference AI. Hosted by the Gigabit Libraries Network, in association with the International Federation of Libraries Associations and Institutions (IFLA), headquartered in The Hague, Netherlands, this conversation explores how new technologies like HSML (Hyperspace Modeling Language) and HSTP (Hyperspace Transaction Protocol) will enable decentralized AI, ushering in and enabling an entirely new kind of intelligent agent, while bridging all emerging technologies across the internet with a unified common language.

Denise explains how VERSES AI and the Spatial Web Foundation is leading the charge in this paradigm shift by developing and donating the protocol and IP for the Spatial Web to the IEEE, setting the stage for global adoption. This new AI, based on world-renowned neuroscientist, Dr. Karl Friston's Free Energy Principle, mimics biological intelligence, offering sustainable, explainable, and human-governed AI systems. Learn about the potential of the Spatial Web to power Smart Cities, decentralized AI, and autonomous intelligent agents, transforming everything from data privacy to real-time AI decision-making.

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Find Denise Holt’s articles on her blog, and join our monthly Learning Lab LIVE: https://deniseholt.us/

Join the waitlist for our all new E-Learning courses for Active Inference AI and Spatial Web Technologies: https://emmersionpublishing.com/course-pre-launch-waitlist/

https://aixglobalmedia.com/

#SpatialWeb #ActiveInferenceAI #HSML #DecentralizedAI #SpatialComputing

AI-ify's AI in Media & Entertainment Summit on June 2, 2024 wrapped up with a final panel that was so engaging to the audience, it continued far past its allotted time and well into the evening's networking cocktail hour. They brought the beer into us! #decentralizedai #ActiveInferenceAI

The panel was hosted by Robert Scoble, and included panelists: Denise Holt, X. Eyeé, Eliza Tan, and Talbert Herndon

The discussion focused on the future of AI, AI safeguards, decentralized AI, the Spatial Web, Active Inference AI, and so much more.

HUGE thank you to Steven Echtman for facilitating this event and allowing it to unfold into the longest panel of the summit - giving voice to all the audience members who wanted to ask questions, and providing the space and time for such an important discussion on AI.

LinkedIn Links:

Steven Echtman: https://www.linkedin.com/in/stevene/

Robert Scoble: https://www.linkedin.com/in/scobleizer/

Denise Holt: https://www.linkedin.com/in/deniseholt1/

X. Eyeé: https://www.linkedin.com/in/techwithx/

Eliza Tan: https://www.linkedin.com/in/elizatan1/

Talbert Herndon: https://www.linkedin.com/in/talbert-andre/

AI-ify event information and links here: https://aiify.io/events/20240601-02sf/

Learn more about Active Inference AI and the Spatial Web on my blog here: https://deniseholt.us/

Join the Spatial Web AI Substack and find out how to tune into our exclusive invite-only monthly Learning Lab LIVE sessions here: https://deniseholt.substack.com/subscribe

AIX Global Media: https://aixglobalmedia.com

#ActiveInferenceAI #SpatialWeb #VERSESAI #DecentralizedAI

Denise Holt speaking at AI-ify's AI in Media & Entertainment Summit on June 2, 2024, regarding how Active Inference AI and the Spatial Web are redefining media. #DecentralizedAI #ActiveInferenceAI

HUGE thank you to Steven Echtman for inviting me to speak and participate in your event. You can find Steve on LinkedIn here: https://www.linkedin.com/in/stevene/

AI-ify event information and links here: https://aiify.io/events/20240601-02sf/

Learn more about Active Inference AI and the Spatial Web on my blog here: https://deniseholt.us/ Join the Spatial

Web AI Substack and find out how to tune into our exclusive invite-only monthly Learning Lab LIVE sessions here: https://deniseholt.substack.com/subscribe

AIX Global Media: https://aixglobalmedia.com

#ActiveInferenceAI #SpatialWeb #VERSESAI #DecentralizedAI

Spatial Web AI Knowledge Bank - Audio Narration of Denise Holt's article written January 10, 2024 - Ultimate Resource Guide for Active Inference AI. #ActiveInferenceAI #VERSESAI #KarlFriston

The Most Complete Repository of Research Links and Educational Content on the VERSES AI Technology & Active Inference AI

-- Get your copy of the Ultimate Resource Guide for Active Inference AI - Join my Substack Community and be sure to select one of the membership levels that include the guide!

Join here: https://deniseholt.substack.com/subscribe

Original Full Article here: https://deniseholt.us/the-ultimate-resource-guide-for-active-inference-ai-2024-q1

Want to learn more about Active Inference AI and the Spatial Web Protocol (HSTP & HSML)? Visit the Spatial Web AI website: https://deniseholt.us

Building amazing AI tools? Find out how to be spotlighted on our show: https://aixglobalmedia.com#ActiveInferenceAI #VERSESAI #HSML #HSTP #SpatialWeb

Spatial Web AI Knowledge Bank - Audio Narration of Denise Holt's article written January 1, 2024 - Hello 2024:   The Year Computing Changes Forever. #ActiveInference #VERSESAI #HSML Original Full Article here: https://deniseholt.us/hello-2024-the-year-computing-changes-forever/ In this video, we explore the groundbreaking advancements made by VERSES AI in 2024, a year that is set to revolutionize the world of computing. VERSES AI has been at the forefront of developing a new framework for computing, going beyond the realm of Generative AI and creating a platform that facilitates the world's interaction within a network of shared intelligence powered by AI. VERSES AI's cutting-edge technology is built upon the principles of Active Inference, a concept that mimics biological intelligence and enables AI to perceive, learn, and act on the world in real-time. By utilizing the Spatial Web Protocol (HSTP) and the Hyperspace Modeling Language (HSML), VERSES AI has established a common global network that links all legacy, current, and future technologies together, providing a foundation for interoperability and context-aware computing. As we enter 2024, VERSES AI is poised to make significant strides in the development of Artificial General Intelligence (AGI). With strategic partnerships with NASA, Volvo, Cortical Labs, Nalantis, and SimWell, VERSES AI is set to demonstrate the real-world applications of their technology across various industries. Their AGI breakthrough, announced just days before Christmas 2023, along with the rollout of their Genius platform, marks a defining moment in the history of computing. As we witness the unfolding of this new era, VERSES AI stands at the forefront, shaping the future of AI and computing as we know it. Want to learn more about Active Inference AI and the Spatial Web Protocol (HSTP & HSML)? Join my Substack Community! https://deniseholt.substack.com/subscribe Visit the Spatial Web AI website: https://deniseholt.us Building amazing AI tools? Find out how to be spotlighted on our show: https://aixglobalmedia.com #ActiveInferenceAI #VERSESAI #HSML #HSTP #SpatialWeb