What happens when a woman in her 40s decides she’s not done—not physically, not mentally, not in the story she’s writing for herself? In this powerful episode, Randi Zuckerberg shares how a postpartum low point became the catalyst for one of the most remarkable midlife athletic transformations ever documented.

Once unable to run a single mile, Randi is now an elite ultramarathoner completing 100–250 mile races, breaking barriers, rewriting the playbook for perimenopausal athletes, and proving that women in midlife are just getting started.

Elizabeth and Randi dive into:
• How functional medicine uncovered the root causes holding her back
• The peptides, recovery tools, and mitochondrial support that changed everything
• Why women’s endurance research is decades behind—and how athletes like Randi are pioneering a new era
• Navigating hormones, recovery, injury, mindset, and the mental toughness unique to women
• What it really takes to train for a 250-mile ultra as a 40-something mom

This is an inspiring, deeply human conversation about resilience, reinvention, and what becomes possible when women stop accepting limitations.

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Episode Description
In this episode, Elizabeth sits down with longevity expert Nathalie Niddam to demystify the world of peptides and bioregulators—and how to use them wisely, not wildly. They break down what peptides actually are, how bioregulators can help restore youthful DNA expression, and why mitochondrial peptides and GLP-1s (like semaglutide/tirzepatide) can be powerful or problematic depending on your terrain. You’ll hear clinical stories about BPC-157, GHK-Cu, epitalon, and oxytocin, plus a fascinating look at plasma exchange, exosomes, and regenerative therapies for aging in a toxic world. Most importantly, Nathalie and Elizabeth keep bringing it back to foundations—nutrition, detox, movement, sleep, and testing—so you understand how to stack these advanced tools on top of real health, not instead of it.

Nathalie Niddam is a Certified Holistic Nutritionist, longevity and biohacking coach, and one of the leading voices in the peptide and bioregulator space. With a background in physiology, nutrition, and functional health, she helps people extend their healthspan by combining ancestral health principles, modern science, and cutting-edge tools like bioregulator peptides. Nathalie hosts the popular podcast “Longevity with Nathalie Niddam,” runs a thriving membership community, and regularly speaks on international stages about healthspan optimization and regenerative therapies.

Listen to: Nathalie's Podcast

Visit: Nathalie's Website

Join her: Longevity Community

Suppements/Peptides Mentioned in this Podcast:

Oral-Dissolving GHK-CU

Oral-Dissolving BPC-157

Oral-Dissolving CJC-1295

Oral-Dissolving PT-141

Oral BPC 157 Supplement

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Disclaimer:
The information in this podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Peptides, bioregulators, GLP-1 medications, hormone therapy, and other therapies discussed in this episode are often off-label, highly individualized, and may not be appropriate or safe for everyone.

Do not start, stop, or change any medication, supplement, or health protocol based on this episode without speaking with your personal healthcare provider. Always consult your own qualified physician, PA, NP, or other licensed practitioner who knows your history before implementing anything you hear on this show.

No doctor–patient relationship is created by listening to this podcast, and individual results will vary. Any mention of specific products, services, or companies does not constitute an endorsement, and no financial relationship is implied unless explicitly stated.

In this episode, Elizabeth Tringali, PA-C, sits down with Dr. Brad Youngren — former U.S. Army combat physician, longevity expert, and CEO of Circulate Health — to explore one of the most promising breakthroughs in regenerative medicine: Therapeutic Plasma Exchange (TPE).

They discuss how this hospital-grade therapy is now being used for healthy aging, detoxification, and chronic disease recovery, and what the Circulate Trial revealed about reducing biological age by 2.6 years.

From microplastics and mercury removal to Alzheimer’s research and POTS recovery, this is your deep dive into how TPE may help reset inflammation, rejuvenate the blood, and extend healthspan.

Learn more about Therapeutic Plasma Exchange HERE

Learn more about Circulate Health HERE