Pomegranates Help Heal An Ailing Intestine
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Pomegranates Help Heal An Ailing Intestine
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The compound produced by gut bacteria after eating foods such as pomegranates, walnuts and berries helps repair intestinal linings. This from gastroenterologists at
the University of Louisville who published their studies in the journal Nature Communicatons.
The studies center on the microbial byproduct urolithin A or UroA, produced when gut bacteria digest pomegranates, walnuts, or berries. The UroA activates a cascade of compounds including aryl hydrocarbon receptor followed by the NLRP6 that triggers a protective effect which helps repair intestinal lining barriers, increases quantities of protective mucus, and strengthens antimicrobial defenses.
These beneficial effects were demonstrated in single cell models, intestinal organoids, and tissues from patients with inflammatory bowel disease.
*The researchers predict that this discovery could lead to more preventive treatments for Crohn’s disease and ulcerative colitis. Such therapy would restore intestinal defenses rather than broadly suppressing the immune system, which is standard current approach.
The references for this report are available on my website.
#InflammatoryBowelDisease #IBD #GutHealth #CrohnsDisease #MedicalResearch