U.S., Israel and Iran trade new strikes as conflict escalates; 3 U.S. service members killed in Iran military operation; Attack on Iran threatens to explode into wider Middle East conflict; and more on tonight’s broadcast.

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Trump says Iran’s supreme leader killed in strikes; Iran unleashes attacks on multiple Arab countries; What comes next inside Iran?; and more on tonight’s broadcast.

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Former President Bill Clinton testifies in Epstein investigation; Father of school shooting suspect takes stand in his own defense; FBI analyzes hours of video in Nancy Guthrie search; and more on tonight’s broadcast.

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New video of car overnight near Guthrie home; Former Secretary of State Hillary Clinton testifies in Epstein investigation; American citizen among victims in Cuba boat shooting, U.S. officials say; and more on tonight’s broadcast.

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Cuba kills four on Florida boat; Deep snow impacts response to Massachusetts house explosion; Trump focuses on economy in State of Union speech; and more on tonight’s broadcast.

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Savannah Guthrie announces $1 million reward for any information leading to her mother; Trump set for State of the Union speech in primetime; New risks from historic blizzard; and more on tonight’s broadcast.

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Record setting blizzard slams Northeast; Historic blizzard grounds nearly all air travel in Northeast; American tourists scramble amid cartel violence in Mexico; and more on tonight’s broadcast.

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Blizzard warnings issued as massive winter storm takes aim at East Coast; New details about shooting death of U.S. citizen in Texas involving federal agent; NASA’s moon mission likely delayed over new problem; and more on tonight’s broadcast.

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