The discussion covered various local and regional issues for 2026. In St. Louis County, the county executive race saw unexpected announcements from Sam Page and Steve Elman. St. Charles County's race features Steve Elman against Jason Law and Bill Igle. Budget cuts in St. Louis County reduced a $40 million deficit to $1 million, using NFL Rams settlement money. The Francis Howell School District's April elections will be closely watched. Redistricting in Missouri added a Republican seat. Downtown Chesterfield's development will continue with vertical construction expected in 2027. St. Charles County's growth and data center developments were also discussed. AI's impact on various industries was noted.

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The West and Mid Rivers Insider Podcast discussed the results of the "Best of West County" awards. With 89,310 votes cast, notable winners included Lucky Dog Central (Best Coffee Shop), Clancy's Pub (Best Burger), and Faraci (Best Pizza). Other highlights included Friendship Village (multiple categories), Parkside Grill (Best Overall Restaurant), and Mulligan's (Best Sports Bar). In senior living, Friendship Village dominated, and in sports, the St. Louis Cardinals won. The podcast also touched on local personalities, businesses, and community leaders, emphasizing the importance of community engagement and support for local enterprises.

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The West and Mid Rivers Insider Podcast discussed the decline in drug overdose deaths in the U.S., with 80,000 deaths in 2024 compared to 110,000 in 2023. Colin Dickey, Assistant Special Agent in Charge of the DEA St. Louis division, attributed the success to relentless enforcement, community education, and the use of Narcan. The DEA seized 586 pounds of fentanyl and 360,000 counterfeit pills in 2025, potentially saving 20.4 million lives. The Fentanyl Free America initiative in October 2025 resulted in the seizure of 45 million counterfeit pills and over 9,000 pounds of fentanyl nationwide.

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