Sam Harris speaks with Rob Reid about biosecurity, pandemic risk, and the alarming fragility of our defenses against biological catastrophe. They discuss the controversial USAID program DEEP VZN, the dangers of gain-of-function research, open science norms that could arm bad actors, the role of AI in accelerating bioweapon development, biosurveillance tools, lone wolf bioterrorists, chaos agents, and other topics.

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In this latest episode of the More From Sam series, Sam and Jaron talk about current events. They discuss whether the U.S. was right to take military action against Iran, the new era of American amorality, antisemitism on the left and right, Tucker Carlson's provocative interview with Mike Huckabee, navigating feelings of hopelessness and dread, the dangers and promise of psychedelics, the corrosive effects of social media on culture and politics, and other topics.

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Sam Harris speaks with Garry Kasparov about the erosion of American democracy and the global authoritarian threat. They discuss Trump's systematic corruption, the GOP's moral collapse, the 2026 midterms as a decisive moment for democracy, Trump's entanglement with Russia and Putin, what a Ukrainian victory would mean for the free world, why Putin's nuclear threats are a bluff, and other topics.

If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.