This episode does a deep dive into a two-year, randomized-controlled trial, investigating the effect of menopausal hormone therapy (MHT) on bone mineral density (BMD) in postmenopausal women. The study compared different dosages of conjugated equine estrogen (CEE) combined with either micronized progesterone (MP) or dydrogesterone (DHG) across three groups. Researchers measured changes in lumbar and hip BMD, along with bone metabolism biomarkers like ALP, Ca, P, Cr, and Ca/Cr, to evaluate treatment effectiveness and safety.

Zuo H, Sun A, Gao L, et al. Effect of Menopausal Hormone Therapy on Bone Mineral Density in Chinese Women: A 2-Year, Prospective, Open-Label, Randomized-Controlled Trial. Med Sci Monit. 2019;25:819-826. Published 2019 Jan 28. doi:10.12659/MSM.912166

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This episode does a deep give into a systematic review and meta-analysis investigating the connections between social media use (SMU), problematic social media use (PSMU), mental health, and sleep in young individuals. The research synthesizes findings from a large number of studies to understand these complex relationships, particularly noting the inconsistent results in previous literature. The authors aim to identify specific associations, determine directionality where possible, and explore potential moderating factors like geography, age, and gender.

Ahmed O, Walsh EI, Dawel A, Alateeq K, Espinoza Oyarce DA, Cherbuin N. Social media use, mental health and sleep: A systematic review with meta-analyses. J Affect Disord. 2024;367:701-712. doi:10.1016/j.jad.2024.08.193

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This episode dissects a qualitative study exploring patient expectations of healthcare providers concerning healthy aging. The research, based on focus group discussions with a diverse age range, identified three core themes: patients desire respect and collaboration from their providers, seek alternatives to medication including lifestyle interventions, and prioritize preventative care over solely treating existing conditions.

Duplantier SC, Undem T. Patient Expectations: A Qualitative Study on What Patients Want From Their Healthcare Providers to Support Them in Healthy Aging. Am J Lifestyle Med. Published online May 21, 2025. doi:10.1177/15598276251344856

Follow Dr. Anthony Novello, PT, DPT

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@anthonynovello.dpt⁠