This episode does a deep dive into an article titled "Relationship Between Tendon Tissue and Shoulder Disability Change During an 8-Week Exercise Intervention for Rotator Cuff Tendinopathy: An Observational Study," which was published in the PTJ: Physical Therapy & Rehabilitation Journal. This prospective longitudinal study sought to understand how changes in the supraspinatus tendon's thickness and internal architecture relate to patient-reported shoulder disability improvement during an eight-week progressive resistive exercise program for individuals with rotator cuff tendinopathy.

Vila-Dieguez O, Heindel MD, Zipser MC, Mortazavi K, Kulig K, Bashford G, et al. Relationship between tendon tissue and shoulder disability change during an 8-week exercise intervention for rotator cuff tendinopathy: an observational study. Phys Ther. 2025;105:pzaf107. doi:10.1093/ptj/pzaf107.

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This episode details experimental evidence demonstrating that paternal exercise in mice, either via treadmill training or muscle-specific genetic overexpression of PGC-1α, transmits enhanced endurance capacity and metabolic health to offspring.

Yin X, Anwar A, Yan L, Yu R, Luo Y, Shi L, et al. Paternal exercise confers endurance capacity to offspring through sperm microRNAs. Cell Metab. 2025;37:1-18. doi:10.1016/j.cmet.2025.09.003.

Follow Dr. Anthony Novello, PT, DPT

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This episode does a deep dive on a systematic review and meta-analysis examining the effects of voluntary slow breathing on heart rate and heart rate variability. This extensive scholarly work synthesizes existing evidence to determine if voluntary slow breathing (VSB) influences the parasympathetic nervous system, specifically focusing on changes in vagally-mediated heart rate variability (HRV). The authors conducted a quantitative review of 223 studies, analyzing HRV parameters at three time points: DURING a breathing session, IM-AFTER1 immediately following a session, and AFTER-INT after a multi-session intervention.

Laborde S, Allen MS, Borges U, et al. Effects of voluntary slow breathing on heart rate and heart rate variability: A systematic review and a meta-analysis. Neurosci Biobehav Rev. 2022;138:104711. doi:10.1016/j.neubiorev.2022.104711

Follow Dr. Anthony Novello, PT, DPT

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