LSU visits Ole Miss in one of the biggest games of Week 3—and breaking Sam Leavitt injury news adds another huge variable to an already fascinating rivalry matchup. College Football with Sam joins Galen Clavio and Matt Blaszka to preview the best games across the national college football schedule.

The guys begin with Houston at Texas Tech, a potentially revealing test for a Red Raiders team that hasn’t yet looked like the clear Big 12 favorite many expected. Can Houston change the conversation around the conference, or is Texas Tech ready to start looking like the contender it was supposed to be?

Then the pressure rises on several high-profile programs. Clemson faces North Carolina with Dabo Swinney suddenly dealing with real questions about the direction of the program, while Florida State hosts Alabama amid growing uncertainty surrounding Mike Norvell.

The guys also break down NC State-Vanderbilt, a massive ACC matchup between SMU and Louisville, Mississippi State-South Carolina and a fascinating Florida-Auburn game between two programs trying to establish themselves under new coaches.

Then comes the main event: No. 7 LSU at No. 8 Ole Miss. The revenge factor is enormous, Trinidad Chambliss has been playing at a high level, Lane Kiffin returns to Oxford—and during the show, LSU quarterback Sam Leavitt is listed as doubtful. Galen, Matt and Sam debate whether Ole Miss is positioned to make a major early-season statement.

Plus: Rutgers-USC, Miami-Wake Forest, UCLA-Purdue, Colorado-Northwestern and other games worth watching around Week 3.

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