In this powerful episode of In Sickness, Bob Coughlin and Paul Kidwell explore what happens when caregiving ends not gradually, but suddenly - with the death of a spouse. Overnight, caregivers lose not only the person they love, but also the identity, structure, and purpose that defined their daily lives. This transition is profound, disorienting, and rarely discussed openly.

Clinical psychologist Barry Jacobs, a nationally recognized expert on family caregiving, joins the conversation to help unpack the emotional, relational, and psychological shifts that follow the end of caregiving.

He is joined by two caregivers who have lived this reality:

• Jason Binder - who lost his wife to glioblastoma

• Kathleen Bond - whose husband Jim lived with multiple myeloma for more than 30 years

Host Paul Kidwell also shares his own experience of losing his wife to Parkinson’s and dementia, offering a deeply personal perspective on grief, identity, and rebuilding a life after caregiving.

In honor of Cystic Fibrosis Awareness Month this episode of In Sickness was taped in May and brought together three extraordinary voices whose lives and work intersect one of the most challenging and inspiring frontiers in rare disease: cystic fibrosis.

From the biotech lab to the clinic to the family home, this conversation explores CF through the lived experiences of:

• Mike Cloonan: CEO of Sionna Therapeutics, advancing a new generation of small molecules in development for CF

• Dr. Ahmet Uluer: Director of the Adult Cystic Fibrosis Program at Brigham and Women’s Hospital and Boston Children’s Hospital

• Bob Coughlin: Former CEO of MassBio and father of a son with CF, sharing 25 years of caregiving insight and love

Together, they paint a portrait of CF that is scientific, deeply human, and profoundly hopeful.

Our second annual Henri Termeer Tribute Episode brings together five leaders whose work reflects - and continues to expand - the legacy of one of biotech’s most influential figures. Henri Termeer transformed rare disease drug development by insisting that science, business, and humanity were inseparable. His belief in patient first innovation reshaped an entire industry and continues to guide the people who knew him best.

In this episode, host Paul Kidwell convenes a powerful conversation with:

• Wendy Erler - SVP, Patient Affairs, Sarepta Therapeutics

• Belinda Termeer - Co-Founder/President, The Termeer Institute

• Daniel Fischer - CEO, Tevard Biosciences

• Ana Maiques - CEO, Neuroelectrics

• Bob Coughlin - Managing Director, JLL/former President, MassBio

Together, they reflect on Henri’s enduring impact on rare disease drug development, the evolution of patient centric leadership, and the responsibility today’s innovators carry forward.