Patient One: MDMA, A Recorded Abuse That Toppled a Trial
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Patient One: MDMA, A Recorded Abuse That Toppled a Trial
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著者：
The camera in a therapy room kept recording as Meaghan Buisson lay under the influence of MDMA in October 2015 - footage that later showed her therapist making repeated physical contact with a patient who could not meaningfully consent. How did a preserved recording of abuse inside a federally sanctioned trial fail to stop the study immediately, and what did it reveal about structural loopholes in psychedelic research?
In this episode, we tell what happened to Patient One One in a Phase Two MDMA-assisted psychotherapy trial, how institutional rules allowed a therapist with a lapsed license to work alongside a licensed colleague, and why a decade-old recording eventually reached regulators and influenced a federal advisory vote. What does Meaghan Buisson’s experience reveal about safety, consent, and oversight in clinical trials?
Person: Meaghan Buisson
Event: October 2015 therapy session recording
Organization: MAPS (Multidisciplinary Association for Psychedelic Studies)
Therapists: Richard Yensen and Donna Dryer
Trial Phase: Phase Two for treatment-resistant PTSD
- Buisson enrolled as Patient One One in December 2014.
- The planned cohort size was twelve patients; the trial ultimately treated six.
- Richard Yensen’s psychologist license had lapsed in 2009, five years before Buisson’s enrollment.
- The dosing phase ran until October 2015 with follow-up continuing through June 2016.
- The institution settled with Buisson for fifteen thousand Canadian dollars and a signed waiver.
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