『The Draize eye drop that kept rabbits blind for lipstick』のカバーアート

The Draize eye drop that kept rabbits blind for lipstick

The Draize eye drop that kept rabbits blind for lipstick

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A technician applies a chemical to a rabbit's held-open eye-how did the Draize eye drop expose regulators' trust in animal tests?

The Draize eye drop that kept rabbits blind for lipstick

In this episode, we follow the history behind a single cruel lab procedure and the decades-long mismatch between scientific practice and consumer language. What gap between the Three R's and a shelf label allowed the Draize test to endure?

Person: Charles Hume
Person: W.M.S. Russell
Person: Lady Dowding
Date: 1957
Date: 1959

- A rabbit's head was restrained and eyelids held open while technicians applied chemicals directly to its eye with no anesthesia.
- Regulators accepted the Draize ocular toxicity test because rabbit eyes' low tear production produced longer contact times, seen as a conservative safety margin.
- The Three R's-Replacement, Reduction, Refinement-were proposed in 1957 as a scientific framework to reduce animal suffering without ideological confrontation.
- Lady Dowding coined and deployed the consumer label "cruelty-free" in 1959 to mark non-animal products and founded Beauty Without Cruelty to promote it.
- By the 1970s the "cruelty-free" label crossed to the U.S., carried by Marcia Pearson and Fashion With Compassion, even as institutional testing practices remained entrenched.

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