エピソード

  • How IBAL-Based Wound Care Is Shaping Affordable Healing for Patients and Providers
    2026/08/06

    Welcome back to Health Unlocked. In this episode, Jasen Petersen dives into the patient side of access to innovative wound care solutions like the Ion Gel, spotlighting how patients, providers, and small businesses can get involved in a rapidly evolving healthcare landscape. After exploring the infrastructural and supply-side mechanics in previous episodes, today’s conversation shifts to practical questions: How is this work being funded? Where can patients actually access these products? And what are the challenges for clinics and practitioners seeking to introduce new treatments? Jasen discusses regulatory pathways, real-world studies happening in Mexico, the importance of affordability, and creative ways ordinary businesses can support healthcare innovation like re-routing credit card processing fees to charitable foundations. Whether you’re a patient hoping for better outcomes, a clinician exploring new protocols, or simply someone curious about the future of patient-driven innovation, this episode is packed with insights you won’t want to miss.


    Timestamps:

    00:00 Discussing foundation's early funding

    04:47 Discussing IP and community involvement

    06:44 Availability of Ion Gel ZCM-25

    12:38 Outsourcing for Safety and Efficiency

    15:09 Insurance impact on wound care pricing

    18:18 Conducting effective placebo-controlled trials

    22:19 Efficacy and cost of cosmetic products

    26:03 Challenges in Tracking Treatment Success

    26:51 IonGel effectiveness and wound healing

    33:27 Challenges with cardiogenic drug training

    34:53 How cell-based treatments work

    38:51 Adjusting cell dosage and frequency

    42:57 Future plans for product distribution

    45:53 From anecdotal evidence to medical use


    “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

    Show Website - https://powerofsalutogenesis.com/

    Ionic Alliance Foundation Website - https://iaf.care/

    Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

    TopHealth Media Website - https://tophealth.care/

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    48 分
  • Navigating Medical Device Classifications and Funding Models for Next-Gen Therapeutics
    2026/07/28

    Welcome back to Health Unlocked, where we dive deep into the real-world challenges and breakthroughs in health innovation. In today’s episode, we’re joined once again by Jasen Petersen, who tackles some of the unanswered questions from previous conversations, this time pulling back the curtain on what “terrain support” actually means for patients and practitioners. We explore how the regulatory landscape shapes which claims can be made about cutting-edge products like Ion Gel, and why certain benefits remain unsaid even when the evidence is compelling. Jasen takes us through the complex process of classifying medical devices, what it means for safety and accessibility, and the strategic thinking behind spinning off development companies to advance multiple health solutions without sacrificing focus or effectiveness. Plus, we get a glimpse into how the future of funding and innovation might look, where collaboration thrives and skepticism, even from the scientific community, drives progress. Stick around for a candid, thoughtful conversation on the intersections of science, regulation, and building something truly new in health care.


    Timestamps:

    00:00 Discovering wound healing insights

    04:24 Class 1 medical device safety

    09:21 Goal of developing Class 1 device

    13:15 Promoting a new wound healing gel

    15:19 Prioritizing safety and funding strategies

    19:24 Observing wound healing process

    22:47 Focusing on wound healing startups

    27:03 Valuing different components of IP

    28:41 Collaborative company operations strategy

    31:39 Drug development and investor milestones

    36:38 Nonprofit funding strategy teaser

    40:52 Community event with parade and helicopter

    42:52 Large turnout for 250th Fun Run


    “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

    Show Website - https://powerofsalutogenesis.com/

    Ionic Alliance Foundation Website - https://iaf.care/

    Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

    TopHealth Media Website - https://tophealth.care/

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    44 分
  • Navigating Patent Strategy and Spinouts for Medical Innovation in Wound Care
    2026/06/29

    The conversation focused on recent developments surrounding a newly granted device patent, often referred to as the "IBAL patent." A key theme that emerged was how this patent, covering ionic cofactor matrices and essential ion delivery for local applications, is shaping the strategy of a nonprofit organization dedicated to advancing this technology across various medical and commercial fields. The discussion explored the innovative spin-out model being used to create specialized development companies for different indications such as wound healing, psoriasis, eczema, and skin cancer, each benefiting from shared intellectual property while maintaining independence.

    Several points were raised, including the reasoning behind a nonprofit holding patents, the benefits and challenges of the collaborative licensing approach, and the significant impact of recent reimbursement changes in wound care markets. Listeners will also hear about opportunities for researchers, practitioners, patients, and capital partners to participate in the mission, as well as new fundraising mechanisms designed to support the ongoing expansion and accessibility of the technology.


    Timestamps:

    00:00 Protecting and promoting the technology

    04:56 Patent Strategy for Medical Applications

    08:08 Collaborative model for IP sharing

    13:08 Finding the right people for niche markets

    16:31 Collaborating on IP development

    18:27 Early manufacturing possibilities

    21:10 Ion gel benefits and cost savings

    25:23 Pricing Strategy and Profitability

    29:38 Support for practitioners and researchers

    33:00 Promoting the podcast and fundraiser

    37:19 Nonprofit collaboration for fee savings

    39:15 Discussing funding challenges


    “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

    Show Website - https://powerofsalutogenesis.com/

    Ionic Alliance Foundation Website - https://iaf.care/

    Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

    TopHealth Media Website - https://tophealth.care/

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    41 分
  • When the Impossible Becomes Possible in Wound Healing
    2026/05/20

    Welcome back to Health Unlocked, where we dive deep into the science and strategy of healing. In today’s episode, we continue our exploration of the power of salutogenesis with Jasen Petersen. Picking up right where we left off, the conversation clarifies critical nuances from the previous episode, especially around the skepticism faced when presenting unexpected wound healing data to the medical community.

    Jasen shares firsthand experiences from clinical work in Mexico, where a novel ion gel, initially introduced as a generic antimicrobial, produced unprecedented results in chronic wound healing, surprising practitioners and raising questions about the product's efficacy and underlying mechanisms. Jasen breaks down why these outcomes appear “impossible” from a conventional medical perspective, discusses the difference between cratogenic and salutogenic interventions, and dissects the challenges of presenting unconventional data to skeptical experts.

    He’ll also cover practical issues in research design, data collection, and the next steps for publication, business development, and bringing this promising therapy to a larger audience. If you’re curious about the future of wound care, cellular healing, or the scientific process itself, this is an episode you won’t want to miss.


    Timestamps:

    00:00 Initial skepticism in Mexico markets

    03:21 Ion gel heals a severe wound

    07:31 Wound healing phases and products

    12:42 Discussing chronic wound healing study

    14:45 Discussing wound healing trials

    18:52 Discussing efficacy and visual results

    22:03 Zinc and copper in scar healing

    26:38 Discussing limitations of cellogenic medicine

    29:32 Publishing the micro immune dynamics paper

    30:49 Discussing study focus on various diseases

    34:17 Dealing with patents and fundraising


    “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

    Show Website - https://powerofsalutogenesis.com/

    Ionic Alliance Foundation Website - https://iaf.care/

    Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

    TopHealth Media Website - https://tophealth.care/

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    36 分
  • Advancing Wound Care: Conference Insights and Surprising Data from Innovative Gel Treatments
    2026/05/07

    Welcome back to Health Unlocked! In this episode, we dive into groundbreaking developments in wound care with Jasen Petersen, who recently attended the Symposium of Advanced Wound Care Conference in Charlotte, North Carolina. Jasen shares his experience presenting compelling clinical data on a novel topical ionic cofactor gel for chronic wounds - data so impressive that it met skepticism from the clinical community. We discuss the challenges of clinical trial design, biases in wound care research, and the hurdles of bringing innovative therapies to market, especially as a nonprofit. Jasen also gives us a glimpse into upcoming research, regulatory roadblocks, and how unconventional paths like decentralized science and industry collaboration might unlock better care for patients with chronic wounds. Stay tuned as we explore the realities, hopes, and frustrations behind changing the status quo in healthcare innovation.


    Timestamps:

    00:00 Talking about the conference experience

    05:54 Discussing survivor bias in data

    08:23 Conducting a prospective study in Mexico

    10:04 Wound healing innovation conference

    15:45 Using pig ECM for wound healing

    19:04 Discussion on clinical trial criteria

    20:10 Limitations of retrospective studies

    25:43 Deciding on data collection strategy

    27:19 Facing funding study challenges

    30:58 Navigating US device approval

    34:56 Personal experiences with a remedy

    38:12 Discussing the pricing of hydrogel

    41:18 Discussing KM analysis for wound closure

    45:12 Building the Ionic Alliance Foundation

    47:22 Product efficacy and user feedback


    “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

    Show Website - https://powerofsalutogenesis.com/

    Ionic Alliance Foundation Website - https://iaf.care/

    Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

    TopHealth Media Website - https://tophealth.care/

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    49 分
  • From 510k to Class 1: A New Pathway for US Market Entry
    2026/04/03

    Welcome back to Health Unlocked: The Power of Salutogenesis, where we explore cutting-edge ideas shaping the future of healthcare. In this episode, Jasen Petersen discusses how Ion Biotechnology is pivoting its US market entry strategy amidst shifting crypto and DeSci (Decentralized Science) market conditions.

    Instead of pursuing the costly and complex 510k regulatory pathway immediately, he reveals a new plan centered on launching the Ion Gel as a Class 1 medical device or even as a cosmetic product, leveraging the terrain support concept. This approach not only allows faster access to the US market and clinical data generation but also provides a foundation for stronger future regulatory submissions. Along the way, he covers the importance of academic publication, community involvement via token funding, and maintaining transparency as the project evolves.

    Tune in to get a real-time look at how innovation, regulation, and community engagement intersect in biotech.


    Timestamps:

    00:00 Finding a cost-effective FDA strategy

    06:17 FDA classification and product function

    09:33 Understanding product claims and regulations

    12:51 Preventing diabetic foot ulcers

    17:15 Overview of the research papers

    21:30 Launching token before DAO

    24:50 Presenting research and generating interest

    27:22 FDA reclassification and strategy

    31:37 Using real-world data for strategy

    35:26 Navigating FDA classification challenges

    38:09 Connecting with Jason and updates

    39:50 Wrapping up the episode


    “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

    Show Website - https://powerofsalutogenesis.com/

    Ionic Alliance Foundation Website - https://iaf.care/

    Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

    TopHealth Media Website - https://tophealth.care/

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    40 分
  • Why Good Intentions Aren’t Enough: Building Structural Accountability in Healthcare Innovation
    2026/03/10

    Welcome back to Health Unlocked! In this episode, Jasen Petersen dives into a topic that’s often underestimated in both startups and massive institutions: why good intentions just aren’t enough to drive lasting, positive change, especially in healthcare. You’ll hear how structural forces, capital pressures, and the limits of traditional governance repeatedly overpower even the most mission-driven organizations.

    Using real-world examples, from the century-long journey of insulin to the rise of tech behemoths like Google, Jasen Petersen explains how systems, not simply personalities or promises, determine outcomes. He breaks down what goes wrong when intentions meet reality, and why scaling up almost always means values get tested to the breaking point.

    Then, the conversation takes a fascinating turn toward solutions: exploring how decentralized science (DeSci), token-based governance, and transparent incentive structures could reshape who holds power and how decisions get made in healthcare innovation. You’ll hear exactly how Jasen Petersen is building new governance models to make sure that, this time, the “right thing” isn’t just a slogan, it’s built into the DNA of the system itself.

    If you’re interested in the intersections of health, technology, economics, and mission-driven innovation, this episode is for you. Let’s get started!


    Timestamps:

    00:00 "Good Intentions vs. Systemic Pressures"

    05:32 "Startup Governance and Capital Evolution"

    08:02 "Healthcare's Free Market Misconception"

    11:28 Aligned Incentives Drive Ethical Governance

    14:51 "Structural Issues in Healthcare"

    18:41 Decentralized IP Licensing Framework

    20:58 "Impact of Poor IP Governance"

    23:47 "Collaborative Data Strengthens Outcomes"

    29:25 "Interconnected Innovation Strengthens IP Strategy"

    33:09 "Mouthwash Innovation Through DSi"

    34:11 "Decisions by Community Wisdom"

    39:10 "DeSci Platform Governance Explained"

    43:05 "Challenges of Broad Technology Applications"

    44:07 "Structurally Durable Innovation Model"

    47:50 "Ion Gel Project Updates"


    “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

    Show Website - https://powerofsalutogenesis.com/

    Ionic Alliance Foundation Website - https://iaf.care/

    Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

    TopHealth Media Website - https://tophealth.care/

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    49 分
  • Bringing Ion Gel to Life: How Restoring Microimmune Health Is Changing Wound Healing
    2026/02/25

    Welcome back to Health Unlocked! In this episode, Jasen Petersen dives into a pivotal moment for the show, moving from discussing big healthcare ideas and frameworks to showcasing a real-world innovation: IonGel ZCM-25. Building on the season’s exploration of how medicine can support the body's own healing processes, he introduces IonGel as the first product built on the IBAL platform: a microimmune nutrient matrix designed to restore local tissue environments and empower true healing.

    The conversation unpacks how this technology, already approved in Mexico and the UAE, differs radically from conventional wound care. Instead of forcing cellular processes with drugs and invasive procedures, IonGel provides essential cofactors like zinc and copper directly to the wound, enabling the body to heal what was previously thought untreatable.

    Drawing on powerful real-world results, from diabetic wounds destined for amputation to stubborn surgical sites, Jasen Petersen shares stories and outcomes that challenge the boundaries of mainstream medicine. The episode also addresses skepticism, regulatory hurdles, and the strategies needed to bring truly disruptive technology to healthcare systems worldwide.

    If you’re curious about how new frameworks in health can become tangible solutions and what it takes to bring them to patients despite resistance, this episode is for you. Get ready for an inspiring look at the convergence of open science, innovative thinking, and the future of medicine.


    Timestamps:

    00:00 "Ion Gel: Bridging Science Movements"

    05:16 "Layers of Wound Care"

    08:37 "IBAL: Micronutrient Matrix for Healing"

    10:35 "Restoring Cellular Self-Regulation"

    15:05 "Ion Gel: Practitioner-Driven Validation"

    19:58 "Challenges in Understanding Broad Efficacy"

    23:50 Laser Kidney Stone Technology

    25:47 "Navigating Paradigm Shifts in Medicine"

    29:39 "Redefining Healing Through Innovation"

    31:50 "Structuring Medicine for Impact"

    34:29 "Skepticism in Wound Healing Innovations"

    37:38 "Revolutionary Healing with Metallic Ions"

    41:05 "Thanks and See You Soon"


    “Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

    Show Website - https://powerofsalutogenesis.com/

    Ionic Alliance Foundation Website - https://iaf.care/

    Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

    TopHealth Media Website - https://tophealth.care/

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    41 分