『HOLOLIFE Summit (Biohacker Summit)』のカバーアート

HOLOLIFE Summit (Biohacker Summit)

HOLOLIFE Summit (Biohacker Summit)

著者： WAS
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Gathering pioneers interested in health opimization, optimal nutrition, high-performance lifestyle and biohacking. Biohacking is the art and science of optimizing your performance and wellbeing with biological & technological tools. Check the links for more information! Disclaimer: The content on this channel is meant for information purposes only. None of the information presented on this channel can be considered as medical advice.Copyright WAS
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  • Why You Lose 90% of Your Stem Cells by Age 30 (Teemu Arina and Christian Drapeau)

    Why You Lose 90% of Your Stem Cells by Age 30 (Teemu Arina and Christian Drapeau)
    2026/03/11
    More information: https://www.hololifesummit.com
    Join HOLOLIFE Academy: https://www.skool.com/hololife-academy/about

    This transcript features a conversation between Teemu Arina and Christian Drapeau regarding the role of stem cells as the body's innate repair system. They discuss how supporting endogenous stem cell mobilization through plant-based supplementation can aid in longevity, recovery, and the management of age-related degenerative conditions. The dialogue highlights the historical context of stem cell research and the impact of lifestyle factors like stress, fasting, and exercise on stem cell function.

    - Stem cells function as the body's primary repair system, similar to the immune or nervous systems.
    - The body experiences a natural 90% decline in circulating stem cells by age 30 as red marrow converts to fatty marrow.
    - Age-related diseases often stem from a deficit where cellular loss outpaces the stem cells' ability to replace them.
    - Endogenous stem cell mobilization involves triggering the release of one's own existing stem cells from the bone marrow.
    - Specific plant extracts can safely stimulate stem cell release for long-term health support without the toxicity of synthetic compounds.
    - A preliminary study showed patients with stable congestive heart failure regained normal heart function after six months of stem cell support.
    - Fasting for more than three days can rejuvenate stem cells through autophagy, making them behave like younger cells.
    - Chronic stress and elevated cortisol levels inhibit the ability of stem cells to migrate into tissues and proliferate.
    - While intense exercise releases stem cells, they are often immediately consumed to repair exercise-induced muscle damage.
    - Delaying the onset of age-related diseases is identified as the most effective strategy for increasing both longevity and healthspan.
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    48 分
  • Bacopa vs Psychedelics: 5‑HT2A Boost Without Trips (Lucas Aoun)

    Bacopa vs Psychedelics: 5‑HT2A Boost Without Trips (Lucas Aoun)
    2026/03/10
    More information: https://www.hololifesummit.com
    Join HOLOLIFE Academy: https://www.skool.com/hololife-academy/about

    The video outlines the rapid growth of clinical research on classic psychedelics and explains that their shared mechanism is activation of the serotonin 5‑HT2A receptor. It then introduces Bacopa monnieri as a herbal source of ebolin lactone, a positive allosteric modulator of the same receptor, suggesting a way to obtain psychedelic-like cognitive benefits without hallucinations. The presenter stresses the need for standardized extracts and notes other compounds that can block the receptor.

    - Clinical trials for classic psychedelics such as psilocybin, LSD, and MDMA have expanded dramatically, showing therapeutic potential for mental health conditions.
    - All major psychedelics produce their effects by agonizing the serotonin 5‑HT2A receptor, a key driver of their subjective experiences.
    - 5‑HT2A receptors are distributed throughout the body, influencing vascular, gastrointestinal, immune, and neural processes.
    - Psychedelic-induced hallucinations stem from 5‑HT2A activation on cortical pyramidal neurons, disrupting thalamic filtering and increasing cortical excitability.
    - Bacopa monnieri, a widely used Ayurvedic herb, contains the compound ebolin lactone, which interacts with the 5‑HT2A receptor.
    - Ebolin lactone functions as a positive allosteric modulator of 5‑HT2A, enhancing serotonin’s natural activity without directly triggering a psychedelic trip.
    - Standardized Bacopa extracts rich in ebolin lactone may replicate micro‑dosing benefits—enhanced cognition, creativity, and sensory processing—without hallucinogenic side effects.
    - Only Bacopa products that are specifically standardized for ebolin lactone show this receptor‑modulating activity; generic supplements do not.
    - Pharmaceuticals such as ciproheptadine, ketanserin, and olanzapine, as well as certain herbal extracts, can block 5‑HT2A and are used to counteract psychedelic effects.
    - Pharma interest is growing in 5‑HT2A activation without hallucinations as a strategy for long‑lasting cognitive and mood improvements.
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    21 分
  • The Nutrition Webinar

    The Nutrition Webinar
    2026/03/10
    It's time to dive deep into the topic of nutrition! Dr. Olli Sovijärvi will take us on a journey to the comprehensive world of nutrition with the many essential ingredients included: vitamins, micronutrients, minerals, antioxidants, and all other essential areas!

    We will cover topics such as:
    - Fat-soluble & water-soluble vitamins
    - Microelements & minerals
    - Fatty acids
    - Amino acids & carbohydrates
    - Antioxidants & oxidative stress
    - How to measure & quantify your nutritional state
    And MUCH, much more…

    More info on our new course, Optimize Your Nutrition:
    https://landing.biohackercenter.com/optimizenutrition

    Biohacker's Handbook, the most comprehensive manual for human health & performance: https://shop.biohackercenter.com/collections/books/products/biohackers-handbook

    Get access to all Biohacker Summit content including the most recent events here: https://landing.biohackersummit.com/2022videopackage

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    Biohacker Center's comprehensive online courses:

    Upgraded Work Life: https://www.upgradedworkplace.com/
    Optimize Your Lab Results: https://landing.biohackercenter.com/labcourse
    Biohacking For Women: https://www.biohackingwomen.com/
    Fortified Immunity: https://landing.biohackingbook.com/fortifiedimmunity
    Optimize Your Gut: https://landing.biohackercenter.com/optimizeyourgut

    Devices, supplements, guides & quality online courses for supporting your health & performance: https://biohackercenter.com/
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    1 時間 47 分
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