The GvHD Hub spoke with Andrew Harris, Memorial Sloan Kettering Cancer Center, New York, US. We asked, What are the challenges involved in enrolling pediatric patients in cGvHD clinical trials?

During this interview, Harris discusses key barriers to enrolling pediatric patients with chronic graft-versus-host disease (cGvHD) in clinical trials, including the limited number of specialist centers with expertise in managing pediatric cGvHD and the resulting need for some children and their families to travel considerable distances to participating sites. He also highlights how the rarity of cGvHD in children may make it difficult to identify eligible patients for clinical trials.

Intended for healthcare professionals. This educational resource is independently supported by Sanofi. All content is developed by SES in collaboration with an expert steering committee. Funders are allowed no influence.

Hosted on Acast. See acast.com/privacy for more information.

The GvHD Hub spoke with Steven Pavletic, Bethesda, US. We asked, What are the key barriers to patient participation in cGvHD clinical trials?

During this interview, Pavletic discusses key factors that may impact patient participation in chronic graft-versus-host disease (cGvHD) clinical trials, including the practical and emotional demands associated with trial involvement, as well as concerns regarding treatment-emergent adverse events and potential long-term effects of investigational therapies. He highlights the importance of empowering patients and involving them in decisions about their care, with clear communication helping to ensure that patients are well informed and have realistic expectations about trial participation.

Intended for healthcare professionals. This educational resource is independently supported by Sanofi. All content is developed by SES in collaboration with an expert steering committee. Funders are allowed no influence.

Hosted on Acast. See acast.com/privacy for more information.

The GvHD Hub spoke with Corey Cutler, Dana-Farber Cancer Institute, Boston, US. We asked, What approaches could improve recruitment and retention in cGvHD clinical trials?

During this interview, Cutler discusses strategies to promote recruitment and retention of patients in chronic graft-versus-host disease (cGvHD) clinical trials. He highlights the importance of broad eligibility criteria, as well as opportunities for patients to participate in both therapeutic and non-therapeutic cGvHD research. He also emphasizes the need to consider the patient perspective when designing trials, including the time, travel, and assessment burden associated with participation.

Intended for healthcare professionals. This educational resource is independently supported by Sanofi. All content is developed by SES in collaboration with an expert steering committee. Funders are allowed no influence.

Hosted on Acast. See acast.com/privacy for more information.