Oregon heads to USC with both programs facing a massive prove-it game, Texas travels to Tennessee for another major test of Arch Manning, and LSU may already be staring at an early-season elimination game against Texas A&M.

College Football with Sam joins Galen Clavio and Matt Blaszka for a loaded Week 4 preview as conference play begins to reshape the college football season.

First, the guys revisit some preseason opinions that have already changed. Oklahoma’s offense has been a major disappointment, Michigan’s defense has far outperformed its offense, while Florida and UCLA have quickly changed the conversation around their new coaching staffs.

Then it’s on to six ranked-vs.-ranked matchups, starting with Oregon at USC. Can Dante Moore and the Ducks recover from their disastrous start, or is Jayden Maiava ready to give USC the signature win it has been waiting for? With Oregon still searching for answers and USC’s defense raising its own concerns, the stakes are enormous for both programs.

Ole Miss also faces a fascinating emotional test at Florida just one week after its huge win over LSU. Can Trinidad Chambliss carry the Rebels again, or is this the perfect spot for Florida?

LSU and Texas A&M meet in what might already be an elimination game, while Texas heads to Neyland Stadium with Arch Manning still trying to prove he can deliver in a hostile road environment against a major opponent.

The guys also break down Michigan-Iowa, undefeated Mississippi State and breakout quarterback Kamario Taylor against Missouri, plus Oklahoma-Georgia, Nebraska-Michigan State, Wisconsin-Penn State, Western Michigan-Boise State, Kansas State-Cincinnati and UCLA-Maryland.

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Ole Miss got its revenge on Lane Kiffin, beating LSU 32-24 in an emotional night in Oxford—and raising some serious questions about the Tigers in the process.

Galen Clavio and Matt Blaszka break down a revealing Week 3 across college football, starting with Trinidad Chambliss, Pete Golding and an Ole Miss team that answered LSU’s second-half comeback with a huge fourth-quarter response. What does the loss say about Sam Leavitt, LSU’s championship ceiling and everything still ahead for Lane Kiffin’s team?

The SEC discussion continues with Florida’s road win at Auburn, Mississippi State’s comeback victory at South Carolina and mounting pressure on Shane Beamer. The guys also reassess Texas A&M, Oklahoma, Texas and an Alabama team whose explosive offense is starting to look increasingly dangerous.

Then it’s around the rest of the country: Notre Dame’s uneven start, Northwestern’s breakout performance, Miami’s shaky second half at Wake Forest, Louisville-SMU and an ACC that remains almost impossible to sort out.

NBC Sports’ Nicole Auerbach joins Football Weather for a rapid-fire conversation about Indiana’s remarkable football transformation, the early state of the Big Ten and one of the biggest games of the season: LSU at Ole Miss.

Auerbach explains why Indiana’s rise under Curt Cignetti has been so unusual, whether the Hoosiers have established a sustainable new floor for the program, and what stands out about Cignetti’s approach behind the scenes.

The conversation then moves nationally. How concerned should we be about the Big Ten after a shaky opening stretch? Nicole weighs in on Ohio State, Oregon, USC, Penn State and Michigan before discussing a bigger question: despite all of the chaos around transfers, roster spending and governance, how healthy is college football itself?

Finally, the group previews an emotional LSU-Ole Miss showdown. Nicole explains why she trusts LSU’s defense, what Trinidad Chambliss brings to Ole Miss and what the game could reveal about LSU as a national championship contender.

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