What if getting older doesn't have to mean getting slower?

On this episode of Endurance State of Mind, Zach sits down with Tony Medrano, CEO and co-founder of LongevityPlan.ai, to take a deep dive into longevity, recovery, performance, peptides, hormones, biomarkers, wearable data, and what it really means to stay healthy and competitive as an endurance athlete gets older.

Tony brings a unique perspective to the conversation. A former U.S. Navy officer, technology entrepreneur, AI and molecular diagnostics executive, and three-time Ironman finisher, Tony has spent years combining endurance training with data-driven health and performance optimization. He's currently training for his fourth Ironman in Cozumel.

The conversation covers some of the most controversial and interesting topics in endurance sports and longevity, including peptide therapy, BPC-157, TB-500, GLP-1s, testosterone replacement therapy, biological age, metabolic age, VO2 max, muscle growth, inflammation, recovery, and the potential role of artificial intelligence in personalized health optimization.

Tony explains why he believes endurance athletes shouldn't focus solely on maximizing VO2 max and why strength training and maintaining muscle become increasingly important as we age. He also discusses his own experience using peptides and GLP-1s, including his dramatic weight loss, changes in recovery, and his approach to using different compounds for different goals.

We also get into the controversy surrounding peptides in competitive sports, including WADA's banned-substance list, BPC-157, testosterone, and the difference between optimizing your health and trying to gain an unfair competitive advantage. Tony makes his position clear: the rules of competition matter, but he views longevity and health optimization differently from competing for a podium.

Later, Tony explains LongevityPlan.ai's Digital Twin, a platform designed to combine wearable data, blood work, DEXA scans, genetic testing, VO2 max and other information into an AI-driven model designed to help athletes better understand their health and performance.

If you're a runner, cyclist, triathlete, ultrarunner, or simply someone who wants to keep performing at a high level for decades, this is a conversation worth listening to.

In this episode:

• Longevity and endurance sports
• How aging affects recovery
• Peptides and athletic performance
• BPC-157 and TB-500
• GLP-1s and weight loss
• Testosterone and TRT
• Biological age vs. chronological age
• Metabolic age and body composition
• VO2 max and endurance performance
• Strength training for longevity
• Muscle mass and aging
• Inflammation and recovery
• Wearables and data overload
• AI and personalized health optimization
• Digital Twins for athletes
• Peptides and WADA regulations
• Tony's journey from the Navy to Silicon Valley to Ironman
• Training for Ironman Cozumel at 55
• How endurance athletes can stay healthy and competitive as they age

Learn more about Tony and LongevityPlan.ai:
LongevityPlan.ai

Connect with Tony Medrano:
LinkedIn: Tony Medrano
Instagram: @tmedranosd
X: @TMedrano2
Facebook: Tony Medrano
YouTube: @LongevityPlanAI

LongevityPlan.ai:
YouTube: @LongevityPlanAI · @LongevityPlanAI-Videos
Instagram: @longevityplanai
X: @longevityplanai
TikTok: @longevityplan.ai
Substack: @longevityplanai
Reddit: u/LongevityPlan_AI
Bluesky: longevityplan-ai.bsky.social
Quora: LongevityPlanAI

For booking & media inquiries:
tony@longevityplan.ai

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