Drs Ursula Matulonis and Jessica St. Laurent discuss endometrial cancer research, funding, early detection, and treatment, including the impact of GLP-1 receptor agonists.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-endometrial-cancer-s3-ep3-2026a10006id. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Endometrial Carcinoma https://emedicine.medscape.com/article/254083-overview

Hereditary Breast and Ovarian Cancer (HBOC): Review of Its Molecular Characteristics, Screening, Treatment, and Prognosis https://pubmed.ncbi.nlm.nih.gov/32862296/

Shifted Assembly and Function of mSWI/SNF Family Subcomplexes Underlie Targetable Dependencies in Dedifferentiated Endometrial Carcinomas https://pubmed.ncbi.nlm.nih.gov/41116019/

Cancer Statistics, 2026 https://pubmed.ncbi.nlm.nih.gov/41528114/

Tirzepatide as an Innovative Treatment Strategy in a Pre-Clinical Model of Obesity-Driven Endometrial Cancer https://pubmed.ncbi.nlm.nih.gov/39388742/

Glucagon-Like Peptide 1 Receptor Agonists and 13 Obesity-Associated Cancers in Patients With Type 2 Diabetes https://pubmed.ncbi.nlm.nih.gov/38967919/

GLP-1 Receptor Agonists Plus Progestins and Endometrial Cancer Risk in Nonmalignant Uterine Diseases https://pubmed.ncbi.nlm.nih.gov/41665904/

TCGA Molecular Prognostic Groups of Endometrial Carcinoma: Current Knowledge and Future Perspectives https://pubmed.ncbi.nlm.nih.gov/36232987/

Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome (SCREEN-CUP) https://clinicaltrials.gov/study/NCT07220239

Circulating Tumor DNA in Endometrial Cancer: Clinical Significance and Implications https://pubmed.ncbi.nlm.nih.gov/39955181/

PTEN Mutations as Predictive Marker for the High-Grade Endometrial Cancer Development in Slovak Women https://pubmed.ncbi.nlm.nih.gov/36592448/

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