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Can antidepressants cause weight gain?

Weight gain is one of the most common concerns people have when starting an antidepressant. While some medications may contribute to weight changes, it’s often not because they directly create body fat. Increased appetite, cravings, fatigue, reduced physical activity, and appetite returning as depression improves can all play a role.

In this episode, holistic pharmacist Larry Pham explains why weight gain can happen, why you should never stop an antidepressant without medical guidance, and practical strategies that may help—including eating more protein and fiber, reducing late-night snacking, adding daily movement, and working with your pharmacist or prescriber if weight becomes a concern.

This episode also introduces the LL Wellness approach: simple, sustainable habits through Eatwell and Livewell that support long-term health alongside your prescribed treatment.

Key Takeaways

• Not all antidepressants have the same effect on weight.
• Appetite, cravings, and fatigue often contribute more than the medication itself.
• Don’t stop your medication without speaking to your healthcare provider.
• Small lifestyle changes can make a meaningful difference.
• Your mental health and physical health deserve equal attention.

Learn more about pharmacist-led wellness: https://llsupplement.com

Explore pharmacist-crafted wellness products: https://www.amazon.com/ll

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