We’re quick to blame genetics for our health and wellness issues, but the reality is that genetics only makes up 18% of our health destiny. That means the rest is up to us.

Our guest today, Dr. Grant Zarzour, has seen that first hand in his own family. When his son was diagnosed with moderate autism, he and his wife refused to accept the predictions for his future. They dove head first into the data and in so doing, revolutionized not just their son’s life, but their own. Now a relentless proponent of diet, sleep, and exercise for physical and mental health, Dr. Zarzour feels like we all have a hand in our own destiny. We just have to commit.

Dr. Zarzour is a practicing hip and knee surgeon in Mobile, AL. He is the president of the largest orthopaedic practice in Alabama. While treating thousands of patients a year, Grant has developed a passion for preventive medicine. In 2024, he founded Sperity Health, which offers personalized longevity coaching to help its members improve their diet, exercise, and sleep with expert MD guidance. Sperity Health’s mission is to lower its member’s risk of cancer, cardiovascular disease, and dementia by up to 50% based on data and science.

With the recent explosion of GLP-1 drugs, the war on obesity seems to have taken a new and potent turn, but many are concerned about the recidivism, the side effects, and our reenergized obsession with being thin.

Our guest today, Dr. Laure DeMattia, is a board certified family medicine physician and obesity specialist. For her, obesity is personal, as she has struggled her entire life with this chronic condition. In this episode, Dr. DeMattia breaks down for us how GLP-1 drugs work to hyperdrive weight loss, why that loss is rarely sustainable without long term use of the drugs, and her own philosophy outside of medication that helps her patients feel seen, heard, and safe. It’s both an educational conversation and a behind-the-curtains look at the obesity epidemic from someone on the front lines.

Dr. Laure DeMattia helps women stop blaming themselves for their physiology and find lasting health for over 20 years. Her dual perspective as both a doctor and a patient makes her uniquely compassionate, challenging the myth that willpower is the solution. Author of the book, The 4 Food Cues, Dr. DeMattia hosts her own YouTube channel, Navigating Obesity with Dr. D, where she offers a compassionate, realistic viewpoint about weight and weight loss.