『Clinical Pharmacology Podcast with Nathan Teuscher』のカバーアート

Clinical Pharmacology Podcast with Nathan Teuscher

Clinical Pharmacology Podcast with Nathan Teuscher

著者： Nathan Teuscher
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概要
 I discuss clinical pharmacology and pharmacometrics topics from the perspective of drug development scientists. I share my expertise and knowledge about designing and conducting clinical pharmacology studies and discuss how to analyze the data using the most effective approaches. I draw from my experience of over 20 years working in drug development organizations and consultancies.Nathan Teuscher 生物科学 科学
エピソード
  • Inter-occasion variability and shrinkage in PK modeling (Ep. 61)

    Inter-occasion variability and shrinkage in PK modeling (Ep. 61)
    2026/10/26

    Today’s episode is about inter-occasion variability and η-shrinkage. Episodes 11, 36, 44, and 45 covered diagnostics, covariate search, estimation methods, and base-model selection. None of them treated occasion variability or shrinkage in population PK modeling. So in today's episode I'll explain what these terms mean and how they may impact your work.


    Links mentioned in the episode:

    • Paper by Karlsson and Sheiner
    • Paper by Savic and Karlsson
    • FDA guidance on Population PK


    Copyright Teuscher Solutions LLC. All rights reserved.
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    23 分
  • Exposure-Response modeling

    Exposure-Response modeling
    2026/10/02

    Today’s episode is about exposure response modeling. What is ER analysis? When is it used? How do you do it? And what tools can be used for ER modeling?

    Links discussed in the show:

    • ICH M15 Guideline
    • You can connect with me on LinkedIn and send me a message
    • Send me a message
    • Sign up for my newsletter


    Copyright Teuscher Solutions LLC


    All Rights Reserved
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    30 分
  • Renal and Hepatic Impairment (Ep. 59)

    Renal and Hepatic Impairment (Ep. 59)
    2026/08/24

    Today’s episode is a discussion of renal and hepatic impairment. I review the biology of the kidney and liver and how we analyze pharmacokinetic data to assess their impact on drug exposure.


    Links discussed in the show:

    • You can connect with me on LinkedIn and send me a message
    • Send me a message
    • Sign up for my newsletter


    Copyright Teuscher Solutions LLC

    All Rights Reserved
    続きを読む 一部表示
    29 分
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